I've been told by people I know who took MDA in the late 70s and during the early-mid 80s that MDA also does that to some people's asses. I've never taken MDMA/MDA or any drugs like it.
I used to have contact and communicate with a few men who liked to PNP as bottoms and they'd take a lot of raw dicks and fists at orgies. No I never had sex with them or even met up with them and they contacted me on sites we were both on.
They'd tell me all about how they loved to take very large dildos and fists/arms even taking more than one fist/arm. No that's not a typo they were FF bottoms too all while on meth, crack/coke, or Ketamine, and some of them also did enemas with booze. They also would tell me how they enjoyed Poppers/Amyl while doing receptive anal sex. I would not recommend any of that and they were HIV+ had other STDs and it would not be surprising if they had multiple strains of HIV or had infected other HIV+ men with other strains. To say that they're suicidal is an understatement.
I've never done any of that and I don't use drugs when I have sex with people.
I personally do not want to bottom at all for anal sex and I would not want to have sex with any man or woman who is on drugs and who wants to do it raw/bare.