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RCs Which is the worst GABAergic sedative you have ever taken? (Benzos, Z-Drugs, ludes, Phenibut, GBL etc.)

Worst by long shot Phenibut, might be a GABA-b like GHB.
But in my experience dose independent, only had effect on severity !
Long lasting nauseating, vertigo causing forcing me to lay down,
and ride it out substance.

1. Best GHB/ GBL of the lot, mostly GABA-b/ GHB receptor.
Euphoric as ....

2. Ethaqualone was bizar vaped instant rush [watch your head !],
Vaped its nothing like GHB, just rush and instant downer.

As 350 mg/ 500 mg/ prescribed was a effective oral dose.
Never tried that but wonder how close to GHB that would rank.
Same for a equivalent dose of Methaqualone and Mephenaqualone.

3. Benzodiazepinen, only 1 re creative imo: Temazepam.
Warm allround/ everlasting Diazepam deserves a place.
Great if you hate Cannabis WD, covers em complete,
only you ll feel drowsy. instead of creative/ energetic.
Also great when in need for a warm long chill.

And the other 3 very good ones,

Etizolam/ DesChloroEtizolam [bit of difference/ overal the same].
It has a sort of pleasant feel for me. Not re creative, but mellow.
Unlike the mainstream Benzo s, its sort of special.

Pyrazolam and Clobazam that are are just super effective,
without the usual side effects as sedation, amnesia, muscle relaxation.
'The background Benzo s', that leave you 100% functional, love the 2.

One that sounds realy realy intriguing,
but is medically discontiued here. CloMethiazole.
That one sounded quite a re creative downer to me.
Only the Sinus side effect you d have to endure.
Clomethiazole feels so interesting. The taste is god awful though. I remember it also rusted my scale in 5 minutes, the spot i had been weighing it rusted very fast. I wonder what it does to your stomach
 
Best: Etizolam followed by Temazepam (for sleep only)
Worst: Zopiclone -> terrible hangover and nasty metallic taste in my mouth for most of the next day.
 
Gabapentin. I could swear it is totally inert.
Isn't its effects on calcium channels, just derived from gaba? Either way, this is probably hands down the worst drug having anything to do with gaba, maybe aside from solvents (ie: GVL, TCE, Chloroform, Ether, etc, though at least solvents actually make you feel different for fucks sake, and this is coming from a guy who used to take 4.5 grams of gabapentin over a day just cause it said it'd make me dizzy).
 
Clonazepam

Never got anything out of it at all, tried it in dosages all the way from 0.5mg to 8mg

Was not good at killing my anxiety, was not as sedating as other benzodiazepines, no noticeable euphoria
Basically always gave me delusions of sobriety above 1mg to the point where I just thought I was sober

It is the only drug that I truly have never found any enjoyment in at all even though I tried taking it probably around 10 - 12 times to try and ”get it”, even nutmeg was more pleasant

Other benzos I have tried include:
Diazepam, Oxazepam, Alprazolam, Lorazepam, Etizolam, Flualprazolam, Clonazolam, Flubromazolam, Nitrazepam

They all gave me ”something” to enjoy, at least that was better than being sober. Clonazepam just made me frustrated and sometimes more anxious that I wasnt feeling ”high” at all
 
The worst GABA drugs for me have always been Benzodiazepines, and short acting are even worse.

For me, I cannot stop myself from compulsively redosing, and the state it puts me in is your quintessential bartard. I will lie, steal, and munch tablets until I run out or it is intervenered.

I have quite literally lost weeks of my life as a teenager in these states, burning every single bridge and being informed of absolutely vile behaviour on my part. It is nothing compared to blacking out on alcohol, waking up losing weeks, in hospital, or in your room to find everyone refusing to talk to you, with no recollection is certainly a experience.

Real Diazepam in small doses (5mg) I have only used responsibly when given a small amount, and its utility is far more so due to its light effects and lovely muscle relaxation.

My issue is my own, and I believe having ADHD, Autism, and numerous mental health issues with a personality disorder (EUPD) in a state of totally suppressed inhibition leads to me living through my numerous base impulses and instincts.

This is my fault and not a blame on diagnosis, but sadly the person I am without a director to reign myself in, and with the exception of Theanine and Lemon Balm, I do not use any GABA substances ever because I know I ruin myself and things for people around me.

The best GABA substance is hands down GHB, it was the least compulsive drug I’ve taken with the greatest positives, great euphoria and puts me in a positive social-able mood without a desire to keep redosing to blackout.

I still don’t think I’d use it again just in case.
 
I have much less experience here with GABAergics than most if you, but I really have a love/hate relationship with benzos in general. They are purely medical for me, they calm my body and mind, but if I take enough to get anything resembling a high, I black out.
 
phenazepam was a train wreck because of the accumulated dosing and benzo black out.

GBL is a fine line as the dose response curve is damn steep and you can end up dead easy

Ambien is a bitch because it is the only GABA drug I consistently black out on

Lyrica is trash and feels like a couple shots of whiskey and some diet pills or something

Alcohol is a neurotoxin and will ruin all of your organs

that is my list.
 
Clonazepam

Never got anything out of it at all, tried it in dosages all the way from 0.5mg to 8mg

Was not good at killing my anxiety, was not as sedating as other benzodiazepines, no noticeable euphoria
Basically always gave me delusions of sobriety above 1mg to the point where I just thought I was sober

It is the only drug that I truly have never found any enjoyment in at all even though I tried taking it probably around 10 - 12 times to try and ”get it”, even nutmeg was more pleasant

Other benzos I have tried include:
Diazepam, Oxazepam, Alprazolam, Lorazepam, Etizolam, Flualprazolam, Clonazolam, Flubromazolam, Nitrazepam

They all gave me ”something” to enjoy, at least that was better than being sober. Clonazepam just made me frustrated and sometimes more anxious that I wasnt feeling ”high” at all

Nutmeg over clonazepam - Blasphemy! Nah -- benzos only give me euphoria if 1. I am actually in a panic attack/severe state of insomnia 2. The dosage exceeds 10mg of xanax/kpin about 80-100 diazepam, etc

Do you smoke the weed? Idk if this is everybody but weed kicks everything in stronger for me. (kind of like they say alcohol does but IME alcohol dirty's the experience)

They aren't everyones cup of tea --- thankgod nothing would get done lol
 
I guess the worst gabaergic I ever tried was gvl. It didnt feel bad per se but it was defenitively the Most useless gabaergic substance i ever tried.
 
Nutmeg over clonazepam - Blasphemy! Nah -- benzos only give me euphoria if 1. I am actually in a panic attack/severe state of insomnia 2. The dosage exceeds 10mg of xanax/kpin about 80-100 diazepam, etc

Do you smoke the weed? Idk if this is everybody but weed kicks everything in stronger for me. (kind of like they say alcohol does but IME alcohol dirty's the experience)

They aren't everyones cup of tea --- thankgod nothing would get done lol
Idk man, most people I know either love clonaz or like me they get absolutely nothing but delusions of sobriety and blackouts from it. It just feels like a memory loss pill for me,
Ive combined it with weed, amph, opiates, alcohol in the past, none of them made it better, it was sort of just a drug I took when I got it for free

My homie whos dead now used to sell clonaz, he usually got 400 blisters/6000 pills at a time and would give me like 3 - 5 pills at random just for sharing a joint with him 😅 miss that dude
 
I'm gonna say Bromazolam was my least favorite of all the GABA drugs I've tried. I loved phenibut for it's mild, long activity and synergy with psychedelics, all benzos go well with any stims IMO even if they suck. Loved pregabalin at doses up to about 1500 mg, I'd go get groceries and feel incredibly loose and euphoric but no swerve like a high dose of xanex or etizolam.

I made a bad choice not long ago and hit a full gram of bromazolam whilst binging harder on meth than I had eve imagined I could... I got hacked and decided I needed to stay up for as long as possible and spend every possible moment remediating the situation. All my active devices and all my accounts aside from my bank accounts got hit because I changed all my passwords due to the somewhat recent 16 billion password and credential hack a while back. So I erred on the side of caution pre incident and at least they didn't empty my lines of credit.

But I think I picked up 7 grams of meth 3 times and half an oz once. Flushed 8 grams once and steadily dovetailed my meth binge use with massive doses of bromazolam to keep the cardiac sides at bay, also taking Viagra and Cialis to help combat vasoconstriction. I finally got a new sim card, phone number, chased the fuckers away but had to constantly reset passwords and contact help from all the account remediation services for all my fucking social media, Microsoft, Google. I was absolutely relentless and I could see the hackers sleep patterns as I stated up for up to 3 days at a time. It was the most reckless drug use ive ever engaged in. Oh ya and they threatened to come to my house and dismember me, so I prepared a pressurized weed sprayer with a torch and some Naphta to spray at a group of up to 4 guys, carried a knife everywhere for a while and took my daily walks with a 10 lb sledge hammer I use for shoulder mobility exercises (I carried it anyways before the exercise to be honest but it at this point served a dual purpose). It was war, I was ready to kill these fucks and I was actively doing OSINT and hunting until a close friend told me to give it up after my accounts stopped fucked with. It was a fucked up month to say the least.

Anyway, a gram of bromazolam will keep you alive during a month long 1 oz meth binge I guess. Never thought I'd be able to tell anybody that from first hand experience.

But back to the benzos, bromazolam on its own (I tried it in place of my ole favourite etizolam that is had the last of a 5 gram batch of not long before this) it left me unable to move properly, like I was swimming in jello, slow slurring speech patterns, thoughts slow and muddy, hard to complete sentences once pushed to what I was expecting to be a nice recreational dose (I think about 4 ish mg? My memory on the dose at the time is hazy). My thoughts came to me as slow and clumsily as my fucking ability to command my limbs, blink was delayed (like not synchronizing 2 eye blinks, it was whack) and the sensation of being barred out *usually* feels nice to me but this was just frustrating and debilitating. Although I could remember the whole experience clearly which is odd.

The monster doses only started after the meth started, steady 5 mg every few hrs, smoking meth out of an elbow bubble attached to a 1.5L bottle as a crude bong setup for Monster hoots with a big Coleman camping torch to blast, water and everything like a psycho. Had the fucking thing in my SUV when I went out places sometimes too packed with ice in the bottom spiked with watermelon cool aid squeeze for a nice flavored hoots. Psychotic right lol.

Anyway, I stopped the meth and then ran REAL low on the bromaz, did not taper correctly and had 2 seizures. Ended up in hospital and actually dislocated and broke my left shoulder from falling flat on my fuckin side, first time at home off a chair, second time on the concrete floor at the hospital. So ya, bromazolam is the worst IMO, no real recreational value. Almost every other benzo I've ever tried at the right dose actually clears my head and helps me think clear, a little more makes for a nice swerve, and I historically liked mixing a beer or 2 with low to medium dose of benzos and a few dexadrine to sit down and jam out on some videogames for a few hrs.

I miss etizolam. And now I have a little bit of a meth addiction, but reading the forums is helping me make some sense of what's happening neurologically.

I'm on semax and Selank to help iron out some of the obvious brain damage the binge has caused, and I'll likely try my Meantime I've been sitting on a gram of for about 5 ish years (idk why but I've been nervous to try it, Makes 0 sense after the horror story I just detailed to my BL fam...) alas I am an imperfect being.

Now I have like a quarter oz of speed and 2 grams of avisaphone and I'd like to shelf it and make a conservative dose schedule for the occasional night out or game night in.

But that's enough of my rambling. I do love a good speedball. Fucking ADHD and executive function is such a bitch lol

Oh ya and the zopliclone "blue canoes" were some of my first benzo experiences. 2 of those and a few shots of hard liquor and man, anxiety evaporated. I guess that was a big attraction for me to the class is the anti anxiety aspect. The temporary bliss is extremely desirable to me being so high strung naturally. And temazepam also has a special place in my heart due to its ability to take the Edge off LSD high without killing the visuals.

That was the only thing I disliked about etizolam, it always completely ended the visual aspect of the psychedelic high, unlike in my experience phenibut which added synergistic effects and xanex which was neutral on visual but smoothed out the edginess of the peak of say a tryptamine experience or LSD high.

Honokiol was a pretty interesting one, very clear headspace, not a high feeling at all but clean, focused and sober. Like "extra" sober if that makes any sense. It's magnolia extract and it's also got some sort of cannabinoid effect albeit exceedingly mild, like white tea

GHB I also found Venice but prohibitively expensive and short acting, great for situations where you might have to drive in say like 4 ish hrs or whatever. Amazing for sex. Also I. the gay community its apparently a big deal "T & G" they call it. I understand why it might be a sex cocktail, meth makes you a sex freak and G also kinda can lean you that way if the vibe is right
 
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For me, definitley phenibut. I would only order some when I took too much of my gabapentin and ran out early. The effects were pretty similar, however, I would have to take a super large dose, and take it several hours before I needed the effects, i.e, for work, social outings etc. The side effects were pretty severe (Stomach pains, weird feelings in limbs, super shaky if I didn't eat.) And also taking it everyday is also very bad, which I did until my next gabapentin dose. I finally stopped taking it after ordering some from a website I normally didn't order from, cause' my normal site was out. What I got was NOT phenibut. I mixed the powder into a drink and drank some and felt the most intense anxiety within a few minutes. Not sure what it was, but not phenibut. Screw that stuff.
 
Toss up between alcohol and soma tbh.

Soma probably. At least alcohol only made me shake in withdrawal not in peak zombie state.

Mind you soma never made me violent.

Tough call really.
 
Dunno. Acts on voltage gated calcium channels. Kinda Gabaergic in a subjective way, certainly seems so. Strange that large doses cause seizures though.
 
Dunno. Acts on voltage gated calcium channels. Kinda Gabaergic in a subjective way, certainly seems so. Strange that large doses cause seizures though.
Yeh I can function on 300mg but not at work ,to dangerous cos I'm still a bit clumsy
But 900mg I'm bumping into walls ,can't speak properly. I think a lower dose of 150 would be fine but I'd have to open the capsule and pour half into water ?
 
Does baclofen qualify since it's a simple homologue of phenibut.

I just noted that in the last few years suppliers of research chemicals now offer the two optical isomers as seperate products. I just found it to be sedating in a way that disturbed my balance and produced nausea and other toxic symptoms even at prescribable doses.

If I had to pick the BEST potential replacement for phenibut, I suspect 4-methyl pregabalin would be the best place to begin if one presumes that the biosynthetic methadology was developed but the product never got to market simply because apart from potency (which is 'enough'), it provides no clinical advantage. Legal advantage, possibly, but not clinical advantage.
 
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Does baclofen ualify since it's a simple homologue of phenibut.
Mate, if anyone knows it would be you!

On your advice I have proceeded with greater caution and barely touch my fluoro-phenibut.

Honestly, I think phenibut is a great chemical. Borderline supplement. Makes you feel good if you respect it. Makes you feel shite if you don't.
 
Mate, if anyone knows it would be you!

On your advice I have proceeded with greater caution and barely touch my fluoro-phenibut.

Honestly, I think phenibut is a great chemical. Borderline supplement. Makes you feel good if you respect it. Makes you feel shite if you don't.

Well, I note that para hydroxyation of the aromatic is one of the metabolic pathways of penibut and related a halogen will prevent that so hard to know exactly what goes on.

I figure that while there have been many new ligands designed to replace pregabalin, unless the offer a clinical advantage, pregablin is so cheap, no clinician would use it which has happened many times before now. I only suggested 4-methyl pregabalin because Pfizer seemed to go into the biosynthesis and that's the key to WHY it's so damned cheap. Only 2-3x more potent than the patent, but it seems it's action is very simiar to it's parent.
 
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