indigoaura
Bluelighter
- Joined
- Jan 4, 2009
- Messages
- 1,707
Ok, cool, laugh.
"What is the scientific explanation?" is literally the driving question of this entire thread. If we knew, we would not be trying to figure it out.
Brief backstory...
I once had a friend who turned blue and had a grande mal seizure while rolling. She took the same pills as everyone else. Nobody else had an issue. She had rolled many times before and never had an issue. The general consensus amongst people at the party was, "Well, must have just been her body chemistry on that particular day."
That did not make sense to me. It did not fit within the parameters of what was known about MDMA/MDA or what was known about her. It did not make sense that she would all of a sudden have a seizure due to some random state of her body. So, I started researching and asking a lot of questions, and it turned out she had a knee injury and had taken an anti-inflammatory med called celebrex. Celebrex was one of the CYP2D6 inhibitors, and it was not supposed to be taken with any other meds processed with CYP2D6.
There was a scientific reason why she had the seizure that day. It was not randomness.
Just because we have not figured out the precise reason why so many people are having the same subpar reports from MDMA use, does not mean there is no scientific explanation.
"What is the scientific explanation?" is literally the driving question of this entire thread. If we knew, we would not be trying to figure it out.
Brief backstory...
I once had a friend who turned blue and had a grande mal seizure while rolling. She took the same pills as everyone else. Nobody else had an issue. She had rolled many times before and never had an issue. The general consensus amongst people at the party was, "Well, must have just been her body chemistry on that particular day."
That did not make sense to me. It did not fit within the parameters of what was known about MDMA/MDA or what was known about her. It did not make sense that she would all of a sudden have a seizure due to some random state of her body. So, I started researching and asking a lot of questions, and it turned out she had a knee injury and had taken an anti-inflammatory med called celebrex. Celebrex was one of the CYP2D6 inhibitors, and it was not supposed to be taken with any other meds processed with CYP2D6.
There was a scientific reason why she had the seizure that day. It was not randomness.
Just because we have not figured out the precise reason why so many people are having the same subpar reports from MDMA use, does not mean there is no scientific explanation.