MrIbis
Bluelighter
Hi All,
After much consideration and reading - I've found two possibly decent, yet rather unresearched chemicals that have popped up in the wake of the Mephedrone bebacle.
The first, which is most likely considered an anlogue of MDA, is ... drumroll.... 'benzo fury' or 1-(benzofuran-6-yl)propan-2-amine.. or 6-ADPB or something like that (sorry i'm not cut and pasting at the moment). Now one could say this drug would be considered the desoxy analogue of MDA, as structurally, i'd call it substancially similar to MDA, minus an oxygen atom. Reports i've read on this chemical compare it extremely positively as an MDMA replacement, with little to no noticeable difference, apart from an obvious MDAish psychedelic edge.
The second is an Amino-Indane, 5-IAI or 5-iodo-2-aminoindane. This drug was first created by the Nichol group, and has a very similar pharmacological profile to MDMA. Based on tests in the animal model, it substitutes completely for MDMA in rats trained to differentiate MDMA, MBDB etc from saline. Based on data i've read, which is not to say just bioassay reports - It produces 3 key factors (those which i believe are responsible for the magic):
5-HT release and agonism
Dopamine release and agonism
Norepinephrine release and agonism.
Now these 3 factors alone, probably would create some decent empathetic elements, however - the most interesting is the proportions in which they release, some being far higher and some being lower (i'm still half tired, so later i'll update the thread with that information - as posted by nichol).
Based on the chemical structure, this chemical should NOT be classed as an analogue (aside from its possible MDMA-eque effects) by the analogues act - and should therefore be legal. It has no resemblance to an MDxx chemical, it has no resemblance to the Cathinones or other drugs of the phenethylamine class.
I shortly intend to guinea pig these chems, and i have some hope, based on the miniscule amounts of reports - and the scientific data i have read.
Maybe p_d can better fill in the blanks that i am unable to.
After much consideration and reading - I've found two possibly decent, yet rather unresearched chemicals that have popped up in the wake of the Mephedrone bebacle.
The first, which is most likely considered an anlogue of MDA, is ... drumroll.... 'benzo fury' or 1-(benzofuran-6-yl)propan-2-amine.. or 6-ADPB or something like that (sorry i'm not cut and pasting at the moment). Now one could say this drug would be considered the desoxy analogue of MDA, as structurally, i'd call it substancially similar to MDA, minus an oxygen atom. Reports i've read on this chemical compare it extremely positively as an MDMA replacement, with little to no noticeable difference, apart from an obvious MDAish psychedelic edge.
The second is an Amino-Indane, 5-IAI or 5-iodo-2-aminoindane. This drug was first created by the Nichol group, and has a very similar pharmacological profile to MDMA. Based on tests in the animal model, it substitutes completely for MDMA in rats trained to differentiate MDMA, MBDB etc from saline. Based on data i've read, which is not to say just bioassay reports - It produces 3 key factors (those which i believe are responsible for the magic):
5-HT release and agonism
Dopamine release and agonism
Norepinephrine release and agonism.
Now these 3 factors alone, probably would create some decent empathetic elements, however - the most interesting is the proportions in which they release, some being far higher and some being lower (i'm still half tired, so later i'll update the thread with that information - as posted by nichol).
Based on the chemical structure, this chemical should NOT be classed as an analogue (aside from its possible MDMA-eque effects) by the analogues act - and should therefore be legal. It has no resemblance to an MDxx chemical, it has no resemblance to the Cathinones or other drugs of the phenethylamine class.
I shortly intend to guinea pig these chems, and i have some hope, based on the miniscule amounts of reports - and the scientific data i have read.
Maybe p_d can better fill in the blanks that i am unable to.
