Lazyscience
Bluelighter
maybe it depends on how fit and healthy you are.
-
OD Moderators: Keif’ Richards | negrogesic
RCs The Methiopropamine N-methyl-1-(thiophen-2-yl)propan-2-amine (MPA) Megathread
- Thread starter TMenderoflives
- Start date
- Status
Albion
Bluelight Crew
- Joined
- Mar 7, 2010
- Messages
- 11,066
I wouldn't consider myself particularly unfit. I'm 19, tall, lean, normal teenager shape. Haven't got any complicated medical history to my name. I smoke, which obviously won't help anything.
So it was even more surprising/unsettling when the chest pains started to happen. Nothing I've ever done in life has caused my heart to feel that way before.
Harambulus
Greenlighter
Pete I think going for 6 hours is your problem, just maybe :D.
I was actually worried when I was struck with the crippling depression for the days after. It was quite a relief when it began to clear up. Since we were in 'unknown territory' it was especially relieving.
Also with meph I had this weird twitch in my leg for a couple months after which went when I stopped taking it albeit taking a long time. I think it went when I began exercising again actually as I'd been quite a couch potato for a while.
Try a bit of cardio to blast it off.
I was actually worried when I was struck with the crippling depression for the days after. It was quite a relief when it began to clear up. Since we were in 'unknown territory' it was especially relieving.
Also with meph I had this weird twitch in my leg for a couple months after which went when I stopped taking it albeit taking a long time. I think it went when I began exercising again actually as I'd been quite a couch potato for a while.
Try a bit of cardio to blast it off.
tyrael
Bluelighter
Arrhythmia? Extreme hypertension by the sounds. Or it could be quite possible that this chem interferes with myocardial diastole (which may be the "THUD" you're describing JSPete), amongst other things. That's the thing, the pharmacodynamics are no where near known and by sounds the negatives affects outweigh the positive.
30mg about 9am
30 mins later I was fine, pleased with the new find.
Housework was a good way to expend energy, got too chatty with the Mrs.
Hunger gone but stomach unsettled so ate.
Seemed to be waves of feeling slightly good, slightly bad, but stimulated throughout.
I'd say stick with these tiny doses until more info appears, if it becomes cheap it will be Ok.
Depends if I feel tired tomorrrow.
30 mins later I was fine, pleased with the new find.
Housework was a good way to expend energy, got too chatty with the Mrs.
Hunger gone but stomach unsettled so ate.
Seemed to be waves of feeling slightly good, slightly bad, but stimulated throughout.
I'd say stick with these tiny doses until more info appears, if it becomes cheap it will be Ok.
Depends if I feel tired tomorrrow.
I'm surprised there are so many negative posts on this lately as I have found it quite a mild substance both in terms of high and side effects.
I'm wondering how many of you are actually very experinced with methamphetamine itself as many people hate meth too as it is easy to overdose and this causes paranoia, anxiety and lathargy lasting days and even psychotic breaks, none of which this seems to have to have the potential to do.
However smoking the substance doesn't seem good for the lungs but plugging is perfect. I find it doesn't last as long as meth but I am not one of these who takes meth and cannot sleep for three days without redosing. It a shame is doesn't have the same instant hit as meth but I like the fuzzy warm feeling of it and it doesn't have you climbing the walls after three days on it like meth would. Remember methamphetamine isn't the bees knees it's just popular because it cheaper and longer lasting than coke!!
I'm wondering how many of you are actually very experinced with methamphetamine itself as many people hate meth too as it is easy to overdose and this causes paranoia, anxiety and lathargy lasting days and even psychotic breaks, none of which this seems to have to have the potential to do.
However smoking the substance doesn't seem good for the lungs but plugging is perfect. I find it doesn't last as long as meth but I am not one of these who takes meth and cannot sleep for three days without redosing. It a shame is doesn't have the same instant hit as meth but I like the fuzzy warm feeling of it and it doesn't have you climbing the walls after three days on it like meth would. Remember methamphetamine isn't the bees knees it's just popular because it cheaper and longer lasting than coke!!
ebola?
Bluelight Crew
This one's intriguing from a SAR standpoint: it appears to induce protracted adrenergic symptoms a la mephedrone (this is only a hypothesis, as we lack objective data to confirm). I wonder if there's some sort of toxic metabolite at play (again, a la mephedrone), or if something different all together is operant here.
ebola
ebola
Well I tried this one, took about 700mg in about 24 hours. (smoked, plugged, and snorted)
I never really noticed strong effects, neither euphoria.
As for the comedown, it took me 2 days to feel good again, I had to puke like 3 times, couldnt sleep, couldnt eat, could barely think straight because I had a major headache.
Be careful guys.
I never really noticed strong effects, neither euphoria.
As for the comedown, it took me 2 days to feel good again, I had to puke like 3 times, couldnt sleep, couldnt eat, could barely think straight because I had a major headache.
Be careful guys.
davem
Bluelighter
This is the first RC I seem to be potentially having probs with.....
I received a free sample of 250mg. 150mg I tried various ROAs over several days, not too big doses - didn't really notice anything at all.
Last week I had to drive 250 miles at the end of a long working day, at the end of which I was falling asleep at the wheel on the way home!!!
The night before I tried plugging (for the first time ever of anything) 50mg in a gelcap. Slightest hints that something might have been noticed, but also possibly placebo. I then insuffulated sub 10mg of Butylone, which I've beenfinding to be an amazing potentiator for lots of lovely RCs. Nowhere near an effective dose if used soley, but very effective at potentiating. No massive effect here, but possibly just enough to keep me awake for the journey.
On the evening of the drive, I followed my plan - plug 50mg, followed about 45 mins later by sub 10mg B1 insuffulated. I then insuffulated a further sub-10mg dose of B1 about 2 hours later.
I felt alert and aware for the whole trip, despite amazingly sleep-inducing conditions (dark, minimal other traffic, nothing to concentrate on <yaaawn>) - all went well. Also managed to get to sleep that night with no real problem.
However the following day I was feeling strangely woozy / dizzy. I repeatedly experienced the camera zoom in whilst moving backwards effect and just generally felt crappy all day. I have to say, it could have been anything - change of water / diet / air / - a bug, mixing butylone with it, but, it felt like (and I have sampled lots of RCs of all natures, psychs/stims/disassociatives/cannabanoids etcetc) the MPA was ther problem. I also ended up quite short on the tolerance / temper front and I am one of the most chilled folks you are ever likely to meet.
I won't be trying any more of this as there are plenty of other joys out there that are lots of fun and don't feel dodgy on the 'level 3 self diagnostic test'.....mind you, I also stopped Mephedrone shortly after starting it
xxx
I received a free sample of 250mg. 150mg I tried various ROAs over several days, not too big doses - didn't really notice anything at all.
Last week I had to drive 250 miles at the end of a long working day, at the end of which I was falling asleep at the wheel on the way home!!!
The night before I tried plugging (for the first time ever of anything) 50mg in a gelcap. Slightest hints that something might have been noticed, but also possibly placebo. I then insuffulated sub 10mg of Butylone, which I've beenfinding to be an amazing potentiator for lots of lovely RCs. Nowhere near an effective dose if used soley, but very effective at potentiating. No massive effect here, but possibly just enough to keep me awake for the journey.
On the evening of the drive, I followed my plan - plug 50mg, followed about 45 mins later by sub 10mg B1 insuffulated. I then insuffulated a further sub-10mg dose of B1 about 2 hours later.
I felt alert and aware for the whole trip, despite amazingly sleep-inducing conditions (dark, minimal other traffic, nothing to concentrate on <yaaawn>) - all went well. Also managed to get to sleep that night with no real problem.
However the following day I was feeling strangely woozy / dizzy. I repeatedly experienced the camera zoom in whilst moving backwards effect and just generally felt crappy all day. I have to say, it could have been anything - change of water / diet / air / - a bug, mixing butylone with it, but, it felt like (and I have sampled lots of RCs of all natures, psychs/stims/disassociatives/cannabanoids etcetc) the MPA was ther problem. I also ended up quite short on the tolerance / temper front and I am one of the most chilled folks you are ever likely to meet.
I won't be trying any more of this as there are plenty of other joys out there that are lots of fun and don't feel dodgy on the 'level 3 self diagnostic test'.....mind you, I also stopped Mephedrone shortly after starting it
xxx
Day 1 30mg 9am.
Stimulation, waves of feel good bad, not extreme.
10 pm 1 beer
10.30 1 nytol
Got some poor quality sleep.
Day 2 9am 30mg codeine
Not bad really, expected worse, went to work 2-7.
OK.
I would't do much more of a dose, its gaining a bit to pay back tomorrow .
OK if you have a lazy day after.
Stimulation, waves of feel good bad, not extreme.
10 pm 1 beer
10.30 1 nytol
Got some poor quality sleep.
Day 2 9am 30mg codeine
Not bad really, expected worse, went to work 2-7.
OK.
I would't do much more of a dose, its gaining a bit to pay back tomorrow .
OK if you have a lazy day after.
captain codshit
Bluelighter
When I got this I first tried 10mg sniffed, did notice some stimulant effect.
Chased 30-40mg after that, more euphoric & runs really well. Tastes quite like meth!
Now I'm home & don't have to speak to lots of people I've chased 50mg.
It's not as euphoric as PV or meth IMO, but perhaps cleaner/less sketchy & easier on the head.
Sniffed it does provide some study aid type qualities - 6 page essay done in 2hrs & I'm very happy with it.
Recreationally it's better chased. I can see the doses could get high though & you'd go through alot of it.
Chased 30-40mg after that, more euphoric & runs really well. Tastes quite like meth!
Now I'm home & don't have to speak to lots of people I've chased 50mg.
It's not as euphoric as PV or meth IMO, but perhaps cleaner/less sketchy & easier on the head.
Sniffed it does provide some study aid type qualities - 6 page essay done in 2hrs & I'm very happy with it.
Recreationally it's better chased. I can see the doses could get high though & you'd go through alot of it.
captain codshit
Bluelighter
It does appear quite heavy on the lungs & takes a minute to catch up with you. If your chasing watch doing too much too soon, I'm going to leave it a good while now. Been dosing too frequently. It's a nice clean high but don't expect the euphoria on a plate like PV or meth is.
Edit: still buzzing 1hr after last chase. Weighed how much I've done & I have 300mgs left off 500mg.
Got another 50-75mgs I will chase later, gonna see how long this lasts.
Edit: still buzzing 1hr after last chase. Weighed how much I've done & I have 300mgs left off 500mg.
Got another 50-75mgs I will chase later, gonna see how long this lasts.
Last edited:
rickolasnice
Bluelighter
- Joined
- Apr 19, 2007
- Messages
- 6,810
I notice people are feeling woozy / nauseous the next day.. when me and my girlfriend did it we definately felt like that when it wore off for an hour or so.. Only did ~80mgs each.
Turing Machine
Bluelighter
- Joined
- Jun 16, 2010
- Messages
- 169
I was just reading through the very first volume of the Journal Of Medicinal Chemistry and stumbled on this remembering that some of the kiddies were taking the thienyl meth analog.
From
"Biological Activity in Compounds Possessing Thiophen Rings "
M. Martin-Smith, and S. T. Reid
J. Med. Chem., 1958,
"The 2-thienyl isostere of amphetamine beta ( 2-thieny1)isopropylamine was studied pharmacologically by Alles and Feigen.The threshold dose for pressor activity in anaesthetized dogs was found to be the same as for amphetamine, and the drug had a comparable duration of action. It also had an action similar to that of phenylethylamine when tested on isolated rabbit intestine, but it failed to show CNS stimulation in man. The same compound as well as dl-Beta-methyl-(2-thieny1)isopropylamine was studied for pressor effect and toxicity by Warren et al The thiophen compounds were found to be less toxic than their benzene isosteres. The P-ethanolamine derivative 2-amino- 1-(2-thieny1)ethanal was found to have pressor activity ca. 60 per cent of that of L-ephedrine hydrochloride. The compounds P-[B-pheny1-(2-thienyl)]ethylamine and P-(B-p-methoxyphenyl-(2-thienyl) )ethylamine (XII) prepared by Robinson and Todd were investigated by Graham who found that the first compound stimulated the CNS in mice whilst the second depressed it. Both compounds potentiated the pressor effect of adrenaline in the spinal cat and depressed the carotid blood pressure in the decerebrate cat,. Other 2-thienylaminoalkanes have been prepared and tested for activity and it was found that the pressor activity of the thiophen compounds was strictly parallel to that of the analogous amines in the benzene series. "
It's interesting that they found the primary amine (amphetamine analog) to be inactive in man. It's also interesting that a thiophene analog of PMA where a thiophene ring is inserted between the benzene ring and the ethyl chain and the alpha methyl group is removed has been teested as early as the 1950's. I think a lot of these thiophene analogs appear to be better in animals than people. For example, the more potent thiambutenes while more potent than morphine as pain killers in mice are only 1/5 as potent in pain killing effect in humans, not to mention the fact that the ratio between the oral ed50 to ld50 in mice was about 1:2 in the best cases. I believe there are a few routes where thienyl based recreational drugs could pan out though.
From
"Biological Activity in Compounds Possessing Thiophen Rings "
M. Martin-Smith, and S. T. Reid
J. Med. Chem., 1958,
"The 2-thienyl isostere of amphetamine beta ( 2-thieny1)isopropylamine was studied pharmacologically by Alles and Feigen.The threshold dose for pressor activity in anaesthetized dogs was found to be the same as for amphetamine, and the drug had a comparable duration of action. It also had an action similar to that of phenylethylamine when tested on isolated rabbit intestine, but it failed to show CNS stimulation in man. The same compound as well as dl-Beta-methyl-(2-thieny1)isopropylamine was studied for pressor effect and toxicity by Warren et al The thiophen compounds were found to be less toxic than their benzene isosteres. The P-ethanolamine derivative 2-amino- 1-(2-thieny1)ethanal was found to have pressor activity ca. 60 per cent of that of L-ephedrine hydrochloride. The compounds P-[B-pheny1-(2-thienyl)]ethylamine and P-(B-p-methoxyphenyl-(2-thienyl) )ethylamine (XII) prepared by Robinson and Todd were investigated by Graham who found that the first compound stimulated the CNS in mice whilst the second depressed it. Both compounds potentiated the pressor effect of adrenaline in the spinal cat and depressed the carotid blood pressure in the decerebrate cat,. Other 2-thienylaminoalkanes have been prepared and tested for activity and it was found that the pressor activity of the thiophen compounds was strictly parallel to that of the analogous amines in the benzene series. "
It's interesting that they found the primary amine (amphetamine analog) to be inactive in man. It's also interesting that a thiophene analog of PMA where a thiophene ring is inserted between the benzene ring and the ethyl chain and the alpha methyl group is removed has been teested as early as the 1950's. I think a lot of these thiophene analogs appear to be better in animals than people. For example, the more potent thiambutenes while more potent than morphine as pain killers in mice are only 1/5 as potent in pain killing effect in humans, not to mention the fact that the ratio between the oral ed50 to ld50 in mice was about 1:2 in the best cases. I believe there are a few routes where thienyl based recreational drugs could pan out though.
Last edited:
captain codshit
Bluelighter
It's a pretty average stim. A line of it before doing something is ok, but chased it's just looking for euphoria that isn't there. I did 200-250mg between 9am and about 3pm sniffed/chased. I'd honestly say just sniff 20mg of it. It isn't great though felt harsh on the lungs I'd agree. Wont be bothering buying it.
- Status