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The Big & Dandy Nootropics Thread

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Thanks, KBT... I take most of those occasionally if not continuously. Great list and descriptions, EXCELLENT job, lots of useful info, very helpful to anyone thinking about these, and a "keeper" of a reference post for me.
 
Tianeptine is on par with Hydergine, and if I had regular access to it I'd take it daily... lovely material. Works very well in combination with hydergine. Not much for intelligence, but excellent mood and wakefulness boost - in fact, the ONLY conventional antidepressant to ever work for me.
 
I've been on 2x800mg piracetam, and 2x250mg of choline bitartrate for around 2 weeks now with no noticeablely different increase in focus, memory, or that "tip of the tongue" feeling that some others have spoken about. I'm now looking for something stronger without having to go the prescription route and having to worry about my liver/kidneys long term. I would like to stick to things that I can aquire here in North America, suggestions?
 
I used hydergine years ago and also noticed headaches, but at the time I somehow associated it with smoking tobacco... as the headaches would hit instead of nicotine rushes... just of curiosity, do any of the hydergine headache folk smoke (tobacco/joints)???
 
Really interessting stuff. I am completly New to Nootropics. I have been taking nutritional Supplements for a while (vitamins and omega oils) but I really wanna try out some of these.

Any suggestions where to start? Generally I think I am fine but I could really use some more energy through the day. I get really tired and sleepy at work and am quite knackered once I get home.

I thought of trying some ALCAR?!
How is it with piracetam in the uk? Is a prescription needed?
 
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lol, Katapult, I'm not a PhD, however, it sounds like you are low on vitamin D...

I'm not the moderator here, however, I would highly suggest that if you haven't had any blood testing done for vitamins and minerals, do that first. Sounds like you just have a bad diet, or poor absorbsion...
 
Optimum 25-D plasma levels are around ~40nL. Get some blood work and if necessary supplement. Start with on oil based D3 at 4000IU-5000IU per day for about 4-5 months then get another test.

Take only a quality D3(4000IU+)/K2(~45ug) complex, and a molecularly distilled fish oil at at least 500mg DHA/200mg EPA or as needed. Avoid ALA sources of omegas. Drop all other supplements and analyze your diet before you proceed.
 
delta_9:

Your response has piqued my interest. I had tried to p.m. you, but because I'm not yet a BL, alas, I could not.

My girlfriend and I have been diagnosed with A.D.D. She is on a prescription called dexedrine since the age of 18 (she is now 32), and she takes it voluntarily.

I have been on piracetam for a little while now (a few weeks I think) along with choline bitartrate, and am not seeing the differences that she has by taking one of those pills (I have capped my own pills from powder ordered from a bulk supplier; I have not weighed the pills, but I am packing "0" size pills full, and am taking 3 of them 2-3 times a day with 2x250mg of choline bitartrate)

Granted, I have read the list of side effects on hers, and the laundry list is pretty unnerving (it sounds like a street drug like ecstacy, or meth).

Is there a good supplement, nootropic, or other that we can be on (combination therapy or otherwise) that can help to focus the mind when needed, and reduce the short term memory issues?

We are willing to do nearly whatever it takes to help us out. Please advise us
 
Dude, Dexedrine is pure d-amphetamine. i.e., Speed. What did you think it was? Didn't you at least google the drug name?

Anyway, amphetamines probably not a good long term solution... you get side effects and in pretty short order become tolerant.
 
Piracetam has been known by some to potentiate amphetamine(although data has yet to support this). However(And I can't stress this enough) these are anecdotes only. You may experience potentiation nothing at all, and that is completely normal and nothing to worry about.
If you feel it necessary, up the dose.
For what it's worth, I have taken up to 3g piracetam w/200mg DMAE with placebo at best. I've also does trials with 10mg, 20mg, 30mg, and 40mg amphetamine with piracetam/DMAE amphetamine and still no potentiation.
This is indeed a very variable compound and much research is needed.

Memory Supps? Well, some people have luck with vinpocetine(vin>ginkgo hands down), although the science is sketchy at best. Results are usually on the elderly.

I do hope I was able to help. :) Fell free to PM when you can, I'd be glad to answer any more soefic questions(hoping I have knowledge lol)
 
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lol, Katapult, I'm not a PhD, however, it sounds like you are low on vitamin D...

I'm not the moderator here, however, I would highly suggest that if you haven't had any blood testing done for vitamins and minerals, do that first. Sounds like you just have a bad diet, or poor absorbsion...


My diet is indeed quite good, but vitamin D could be an issue. Living in Scotland and not really working outside could definitely leave me with too little vitamin D. Thanks, will ask my doctor about the vitamins...
 
Agreed. Please tell your doctor to test all vitamins/minerals for good measure...since you're getting stabbed, may as well have 'em take a few more vials.

Yes Dwayne, I knew it was (read a wiki on it).

delta_9 and Delsyd, thank you for the feedback. I would also like a supplement/nootropic that can help focus my mind (I'm currently doing meditation, which helps a lot, but I'd like something more). Any suggestions?
 
Meditation is, from a physiological perspective, shifts from one brain wave frequency, to another. L-Theanine has shown to promote alpha activity.

...hold for source please

The average cup of quality loose, organic japanese tea contains roughly ~40mg-50mg theanine. (I know that's a lot of adjectives but the soil in China is garbage I avoid it at all costs.) Organic japanese matcha is even better for theanine.

I have also read that compounds with GABA system activity(theanine being one of them) can cause rebound anxiety (even if the substance is natural) or they can cause problems for existing neurotransmitter systems which again may not be that easy for your body to recover from or not recommended for daily use. However, you'd be hard pressed to convince me that green tea everyday is bad for you. It's like my water now :D

Link -
NSFW:
http://www.ncbi.nlm.nih.gov/pubmed/18296328
Tea is the most widely consumed beverage in the world after water. Tea is known to be a rich source of flavonoid antioxidants. However tea also contains a unique amino acid, L-theanine that may modulate aspects of brain function in humans. Evidence from human electroencephalograph (EEG) studies show that it has a direct effect on the brain (Juneja et al. Trends in Food Science & Tech 1999;10;199-204). L-theanine significantly increases activity in the alpha frequency band which indicates that it relaxes the mind without inducing drowsiness. However, this effect has only been established at higher doses than that typically found in a cup of black tea (approximately 20mg). The aim of the current research was to establish this effect at more realistic dietary levels. EEG was measured in healthy, young participants at baseline and 45, 60, 75, 90 and 105 minutes after ingestion of 50mg L-theanine (n=16) or placebo (n=19). Participants were resting with their eyes closed during EEG recording. There was a greater increase in alpha activity across time in the L-theanine condition (relative to placebo (p+0.05). A second study replicated this effect in participants engaged in passive activity. These data indicate that L-theanine, at realistic dietary levels, has a significant effect on the general state of mental alertness or arousal. Furthermore, alpha activity is known to play an important role in critical aspects of attention, and further research is therefore focussed on understanding the effect of L-theanine on attentional processes. [3]


I myself take 250mg-300mg L-Theanine most nights but when I run out I may not buy more.

Of course if you're feeling bold you could always chow down on some Boletus Badius mushrooms ;) (http://en.wikipedia.org/wiki/Boletus_badius) Only other source of the animo acid in nature.
 
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cool guys! After speaking to my other half, the best way of saying what I meant was "brain fog", not "focus". We both have a lot of fog that is making us so that we cannot remember what we need to do for the day, and making it hard to concentrate on particular tasks without getting distracted. Will the L-Theanine or the selegeline work for that?

as a side note I like to use gaba to help me sleep and regenerate tissue (recovering from surgery right now).
 
nope, not into relaxing, no anxiety or lack of sleep here...I'm more into helping short term memory and also the brain fog that is causing loss of concentration
 
Piracetam is great for that and works for many people. You can currently still get it in bulk online pretty easily, but I think the FDA (wait, you're in Canada, so I'm not sure) is about to start regulating it. Start with probably 1200mg shortly before you're going to start your day and start doing stuff mentally. It provides subtle effects that you should be able to notice and start working with. It's definitely a mental focuser.
 
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