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The Big & Dandy Nootropics Thread

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help the crohny out...please

I read the first 11 pages, then skipped to the end...always wanted to see what the ending was about...

But seriously, it's a pleasure to have accidentally found this site, and I'm hopeful that one of the more experienced users (ahem...MagickalKat...Jamshyd...etc.) will respond to me sooner than later

Okay, enough arse kissing...I have Crohn's disease AND undiagnosed ADD (a psychologist client of mine told me I have ADD in spades as I am multithreaded thinker, and "all over the place" with my thoughts, and verbiage...starting mid sentence as if I had already had the conversation with the person, yet, it was with myself in my mind).

I have gotten much more foggy in my thoughts, and my memory has gone down the shitter (yes, I know, very punny, thanks crohn's, but no thanks).

I could really use something that will focus my mind, increase my memory, and that I can use all the time, that will not adversely affect the crohn's (unless in a good way; p.s. sorta tired of the herbs and weak ass supplements in the local shops that don't do anything to help with these things...ended up taking a focus pill that was loaded with dha, and a ton of fish oils that were extracted and concentrated, and it did zilch for me; I'm looking for something that has a very noticeable difference, this is why I'm here as I believe this stuff is the key to my success)

I have read about many of the older nootropics (not keeping tabs on the new stuff), and the piracetam sounds good (and I can get it with no problems...currently anyways).

I don't want to increase my pill intake if I don't have to (15-20 pills at once was getting taxing on me first thing in the a.m.)...powders are great because I'm into the blender shakes, or shaken/stirred methods.

Any suggestions? (I can source dosing, unless you have suggestions for that too)

Thank you in advance for taking the time to reading my post, and taking the time to calculate a thoughtful response :)
 
pyro-glutamic acid (quickest way to get racetamic brain-contact-cleaner up here in Canada w/o waiting a week for the mail), wildrose extract, and fish caps by the handful, daily.

Of course, getting the RDA of one's V's and M's, and minimizing contact with oxidizers like ethanol are foregone conclusions...

We have something called Ortho-Mind 1.0, which has Vinpocetine, Bacopa Manniera (sp?), Gingko, the aforementioned pryo-glutamic acid, Huperzine A, L-Carnitine, et al. Seems to do the trick for me quite nicely, although if an individual could only do one of the above, I would have to recommend obscene dosages of Omega 3's... and green tea by the gallon, lol
 
heh, obscene dosages lol

yea, I don't mind waiting a week, that's not bad, took me a while to find a company that still carries the stuff and is willing to ship to canada, the pills are seriously overpriced in comparison to the DIY powder, pill machine method...

wondering if anyone uses a needle-less injection device these days (ala lawnmower man movie)?
 
I've experimented with various nootropics over the years, but I've come to the conclusion that the most effective means of achieving focus, enhancing memory and warding off fatigue is a combination of healthy diet, good sleep, routine exercise and perhaps a cup of coffee.

Piracetam (in combination with a small amount of centrophenoxine to avoid a headache) has a subtle effect as well, but the effect is so mild that I don't feel compelled to use it regularly. DMAE as a choline precursor consistently clouded my thoughts. With piracetam, I notice the effect most in the way that I speak...I feel like I'm able to articulate more easily (i.e. the right words come more effortlessly). This effect is very subtle though, and difficult to definitively distinguish from placebo.

Of the other nootropics I've tried, hydergine produced a subtle change cognitively, but I did not notice cognitive enhancement. Also, there are legitimate concerns about 5-HT2B agonist and fibrotic complications with this drug. I also tried the herbal acetylcholinesterase inhibitor, huperzine A, but never noticed a clear advantage.
 
I haven't really had any experience with nootropics, but they interest me. Right now, I am relying on adderall to get me through the regular all nighters and studying, but I don't want tor rely on a friend's prescription.
I'd like to be able to focus better, have more energy/motivation, and think more clearly, and I'd like to do that without amphetamines. In general, I'm just falling behind in studies, and would like to catch up.
What do you recommend? From what I've seen piracetam is what I need, but I just wanted a second opinion. I was actually thinking about a combo of piracetam and DMAE.
 
I'm interested in taking Pramiracetam, but i've also seen Aniracetam, Oxiracetam and the weaker Piracetam mentioned as decent alternatives.

Do I need to take choline with all of them for them to be effective?

Also, can anyone give some recommended or at least relative dosage levels please?

For example I think Pramiracetam needs a much smaller dose than Piracetam from what I can gather. This will help with working out what is the most cost effective one to get as well.
 
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Deus said:
I haven't really had any experience with nootropics, but they interest me. Right now, I am relying on adderall to get me through the regular all nighters and studying, but I don't want tor rely on a friend's prescription.
I'd like to be able to focus better, have more energy/motivation, and think more clearly, and I'd like to do that without amphetamines. In general, I'm just falling behind in studies, and would like to catch up.
What do you recommend? From what I've seen piracetam is what I need, but I just wanted a second opinion. I was actually thinking about a combo of piracetam and DMAE.
Click to expand...

See the post above yours...nothing is going to replace the energy/motivation of amphetamines without depleting your neurotransmitters (i.e. leaving you with a hangover). The problem with amps is that they extract a steep price for the advantage they provide. In my opinion, they can be useful if used sparingly, but one of the biggest pitfalls is that they impair one's ability to self-motivate and do work without them.

Healthy diet, exercise, regular sleep, and good study habits are the best sustainable means of increasing energy and motivation. That said, academic work will never feel effortless. I think some people have the misconception that people that work hard have limitless motivation...that rarely seems to be the case. Rather, these diligent individuals push themselves constantly. They have high expectations of themselves and they get into a routine of being productive.

I've never pulled an all-nighter for studying, and I can only imagine that regular all-nighters will leave you more cloudy in the head than anything else.

Piracetam (or another in the same class) may be worth experimenting with, but expecting a quick fix is sure to end in disappointment.
 
I've been on Piracetam for the last couple of weeks and i'm not sure if i'm feeling that much from it but I'll persevere and make sure what I think I have felt from it wasn't just a coincidence. It's cheap as chips so no biggie if it does nothing for me.

After further reading though I've added some more nootropics that sound interesting to my stack, so my weekday stack as of tomorrow is:

2000mg Piracetam
2400mg Lechitin (or should I be taking another choline source like Alpha GPC?)
1000mg Aniracetam
2000mg fish oil (reasons including as I hear Aniracetam needs to be taken with a fat source)
100mg Picamilon (hopefully this will provide me with a touch of the feeling Phenibut does but I can take it more often.)
1x A-Z multi-vit

I plan to take this once a day first thing in the morning but I'll try splitting it into 2 doses, (1 in the morning and the other in the afternoon), after I've established positive effect.

Weekends I'll drop some of the above, especially the Picamilon, and take Phenibut, AMT, and sometimes alcohol, caffeine and 6-APB to whatever level I require, be it creative or recreational.
 
Is psychological addiction an issue with nootropics? My drug use along with severe anxiety has put me in a frequently derealized state. The racetams and huperzine a make the world seem real again. It's like switching from a black and white tv to an HD. Everything seems so crisp around me. It's a feeling I find hard to be without when not using them.
 
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ferinox said:
Is psychological addiction an issue with nootropics? My drug use along with severe anxiety has put me in a frequently derealized state. The racetams and huperazine a make the world seem real again. It's like switching from a black and white tv to an HD. Everything seems so crisp around me. It's a feeling I find hard to be without when not using them.
Click to expand...

It can be an issue, but it's hard to classify a psychological attachment to something as benign as a nootropic an "addiction" in the classical sense. I think of addiction as in a behavior one persists participating in despite the obvious harm and consequences to the contrary. At least that's my understanding of the medical definition of addiction, but the common use of that term is stretched so far as to become meaningless. It's often used to guilt small time users and people the medical establishment finds "hard to deal with" due to any number of lifestyle choices which are ultimately up to the user's discretion.

Basically because nootropics aren't prescribed and thus can't be controlled, alot of doctors might tell you that you have an addiction to nootropics. They'll cite your past drug use and current anxiety issues and connect them, saying the nootropics are an extension of a self-medicating mindstate. Thus an "addict" is born. However, all of this is extremely personal and subjective. Under the same criteria your Doc is probably himself "addicted" to caffine, alcohol, or cigarettes-or some combination of all three, all socially acceptable.

In my eyes the only question that matters is: What do YOU want, what brings YOU the most happiness and contentment? Does the cost of huperazine and racetams outweigh the benefits you feel from them? These are the things you should be thinking about, do you want to go back to black and white, or is it the crispness of the world unveiled that makes you want to live life?
 
ugh1979 said:
I've been on Piracetam for the last couple of weeks and i'm not sure if i'm feeling that much from it but I'll persevere and make sure what I think I have felt from it wasn't just a coincidence. It's cheap as chips so no biggie if it does nothing for me.

After further reading though I've added some more nootropics that sound interesting to my stack, so my weekday stack as of tomorrow is:

2000mg Piracetam
2400mg Lechitin 1(or should I be taking another choline source like Alpha GPC?)
1000mg Aniracetam
2000mg fish oil 2(reasons including as I hear Aniracetam needs to be taken with a fat source)
Click to expand...

1. There are better choline sources out there. Centrophenoxine is one of the best and DMAE is not too bad. But lechithin is ok but you need to be sure you're taking enough and the right kind. Lecithin is a mixture of several phospholipids not straight choline, so see how much phosphatidyl choline you actually get from 2400mg lecithin. Also make sure there is not too much linoleic acid(omega-6) and finally make sure it's non-gmo soy :)

2. There is hardly any oil in 2 little fish oil caps. I like to take my fat soluble supplements(omega 3s, Vit D3/K2, & mixed Vit E pherols/trienols) with a tablespoon of pure olive oil. Try something like this but definitily keep the fish oil as well.
 
I've been doing a lot of searching and it seems very hard to find oxiracetam anyone else having this problem?
 
piracetam

found some! yay, bought a kilo and it finally arrived! got myself a pill maker, now I'm ready to go with some choline bitartrate...I can hardly wait, and hopefully with the choline, I'm not one of the ones that will have fish smelling BO.

P.S.
anyone know the ratio of piracetam to choline bitartrate? (800mg of pir to ?mg of choline bitartrate)
 
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I'm currently on another course of Hydergine. I can't overstate how much I LOVE this stuff!! It seems to be the best medicine for intellectual melancholia, btw.

This time around I also tried Nicergoline for the first time and also combined it with Hydergine. It is equally impressive, but seems to also have more sensory effects (making it even more-so than hydergine similar to ULD LSD), but it also tends to give a headache for the first couple of hours so I'm using it cautiously.

Ergolines seem to be such a godsend :). I might consider trying small doses of bromocryptine in the near future...
 
I'd love to skip making the pills and go with a needleless injection technology with the piracetam. Does anyone know of a precedence for this? has anyone ever tried it? (no needles please)
 
^ why skip the pills? getting super stoned and capping stuff is the best.


i've got a needleless syringe that i put mdma in my butt with sometimes tho :D
 
I'm not getting super stoned off of piracetam, or anything else for the matter. I'm looking to increase my awareness, and boost my memory recall. mdma in your butt, ewwww, sounds experimental...whatever you do, don't put an mdma cap in your butt, you may die.
 
I took hydergine for a week and got nothing but headaches. Like a very subtle migraine. What's up with that?

Also, has anyone tried stablon/tianeptine? It's a French antidepressant that enhances serotonin reuptake. I found it to be euphoria inducing and almost imperceptibly psychedelic. I've always wondered what it would be like to take tryptamines on it.

Presumably serotonin and the tryptamines compete for 5ht receptors, so a serotonin reuptake enhancer would potentiate the trip? Well, one time I took a tab of stablon a couple of hours before an 8th of shrooms and the trip hit hard like 7-10 minutes after I ate the shroomies and had the most spectacularly lucid, crystal-clear headed peak I've ever experienced. Can't exactly recommend it to anyone, since I did it unintentionally myself, but maybe someone who understands the pharmacology better could shed some light on this interaction.
 
Nootropics rule!!! :D I really think they saved my mind at a time of potential psychological crisis.
Cramming your brain full of drugs doesn't really seem like an obvious solution to the problems caused by cramming your brain with drugs, but good god were my assumptions wrong. They can even sometimes feel like psychotropic substances in their own right, and you get the added bonus of knowing that you're actually being kind to your brain for once! Anyway enough jabbering about my love for these neurosteroids. Here is my current regimen (daily unless otherwise stated):
Piracetam - 3200/4800mg (split into 2/3 doses), great for general cognitive clarity and musical creation/appreciation. All the nootropic racetams make your verbal fluidity great (like the connection between your thoughts and how you express them).
Aniracetam - When I've got a big supply I just munch (literally) on this sweet chemical at least twice a day. Great anxiolytic, makes me feel energetic and creative, in social situations especially :)
ALCAR - 1000mg, makes focusing easier and seems to raise energy levels.
Centrophenoxine - 400mg Great choline source (along with ALCAR), 2x a week.
Fish Oil - 5000mg, pretty essential.
Ginkgo Biloba - 120mg, Good for energy and if you have vasoconstriction problems.
Galantamine - Makes dreams so insanely clear and recall is increased massively, 4mg 2x a week at night (to keep down tolerance).
Vitamin B-Complex - Important role in nervous system functions.
Chelated Magnesium - 250mg, mild anxiolytic.
Lions Mane - 1500mg at night, Increases dream recalls.
Sulbutiamine - 1600mg Great just before a gym session, large increase of determination and hardiness (sorry thats not really scientific :P). Also massively reduces hangovers if taken before a night of heavy drinking.

Above all I'd recommend the 'racetams. Piracetam imo should be the staple chemical in any nootropic regimen and if you can stretch the dough then Aniracetam is a very worthwhile investment. Also don't forget a choline source when taking these (unless you want a headache).

I haven't tried tianeptine but I've ordered some recently and eagerly await its arrival :) I am really interested in its purported effect of carrying on working after cessation of treatment. Something to do with increasing serotonin receptor density maybe? Don't quote me on that.

To Psychodelirium - At what dosage of tianeptine did you experience euphoria? Also your shroom trip sounds awesome, I'm gonna have to try that mix! To hazard a guess at the mechanism involved in that synergy; Tianeptine acts as an SSRE (selective serotonin reuptake enhancer) which increases the reuptake of serotonin, leading to a decrease in serotonin concentrations in the synapses thus leaving more room for the psilocin to work its magic on the receptors.
 
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