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The Big & Dandy Nootropics Thread

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To be honest, I found phenibut to be minimally useful and produced a withdrawal syndrome upon stopping after a couple of weeks of daily use during benzo withdrawal. I was able to eliminate the possibility of this being somekind of rebound benzo withdrawl by taking benzos. The strange thing is that while taking benzos did limit the anxiety and muscle-tension factor of phenibut withdrawal, they seemed to not have any affect on the excessive sweating, depression, dierrhea, and muscle-pain. This leads me to speculate that phenibut is perhaps not entirely GABAergic, but probably cholinergic as well, perhaps even affecting GHB receptors.

Btw, thanks for the tips on Piracetam end hydergine, guys. I might give both a try sometime.
 
You experienced withdrawal from phenibut? That's odd... I've used it in the past, daily (very regularly) for months and months, and never experienced anything like that at all.

I would not be at ALL surprised if it has a similar method of action as GHB though. It actually is quite similar. Much less in-your-face though.

Jamshyd, your use of phenibut was during a benzo withdrawal, right? Or during a time when you were removing benzos from your life at least?
 
Xorkoth said:
withdrawal from phenibut?
Click to expand...
According to Wikipedia, which as everyone knows is a very reliable source ;) "Phenibut should be used with extreme caution as it can have unpleasant withdrawal symptoms. Side effects can include acute anxiety and insomnia that can last for up to two weeks afterwards."
 
I have heard of anxiety persisting after cessation of phenibut, but I have never heard of the acute physical effects Jamshyd talks about - I would be more inclined to think that they are an effect of withdrawling from the phenibut on top of a benzo withdrawl-

but of course, in some individuals the physical symptoms may manifest - I never have used phenibut more than one day in a row so I cannot personally attest to anything of that nature-
 
Nootropics I use:
Piracetam 1g twice daily
Choline 500mg twice daily
Phenibut 300mg twice daily, 2-3 days per week, more for sleep aid, anxiety, or fun.
Fish oil 2 gel caps twice daily
Ginkgo Biloba, 1-2 times daily
St. John's Wort twice daily (I will stop at least 10 days before tripping)
Caffeine various amounts daily
Modafinil 100mg daily

Not sure if fish oil, caffeine, or St. John's Wort count.
 
Tryptamine*Dreamer said:
Nootropics I use:
Piracetam 1g twice daily
Choline 500mg twice daily
Phenibut 300mg twice daily, 2-3 days per week, more for sleep aid, anxiety, or fun.
Fish oil 2 gel caps twice daily
Ginkgo Biloba, 1-2 times daily
St. John's Wort twice daily (I will stop at least 10 days before tripping)
Caffeine various amounts daily
Modafinil 100mg daily

Not sure if fish oil, caffeine, or St. John's Wort count.
Click to expand...


Fish Oil at such a low dosage surely wouldn't count (I imagine they're 180:120 = EPA : DHA).

Clinical benefits don't really kick in until you're taking at least 500mg (but usually 1000mg) of either.



The caffeine and SJW will exude certain nootropic benefits :)
 
currently 1l green tea daily. (http://en.wikipedia.org/wiki/Sencha)

does baclofen have similar effects compared to phenibut? at least they are not that different on a structural and pharmalogical basis.

and how long do dmae (100mg/d) and hydergine (2,25mg/d) need for start working?
 
DMAE is very strong if taken at about 250mg -

it also dilates my eyes pretty heavily at about T+4 hours -

it is very stimulating - almost drug-like in its swing up (but no swing down)-

for it to really work well I find I must combine it with piracetam - that combo is one smokin' dopaminergic combo-
 
Ever used centrophenoxine, S_S? It's DMAE combined with something else... it's supposed to be better. I have used both and I noticed DMAE more, but that's probably because DMAE was the first nootropic I ever took, when I was depressed, and it made a large difference then.
 
no, I have a small sample of it - but I have never tried it since the DMAE works so very well -

although there are some conflicting reports on DMAE - I think it can have very counter-productive effects if taken in too large a dose (I believe DOndante mentioned this, that if choline donators are not monitored somewhat carefully they can have an anti-nootropic effect)-
 
Xorkoth said:
centrophenoxine, S_S? It's DMAE combined with something else...
Click to expand...
According to a reliable source ;) Centrophenoxine (also called Meclofenoxate, and formerly sold under the brand name Lucidril®) is a drug used to treat the symptoms of senile dementia and Alzheimer's Disease. It is a compound of two biochemicals: dimethylaminoethanol (DMAE) and parachlorophenoxyacetate (pCPA).
 
yes, if I recall correctly the pCPA had something to do with growth regeneration - could be wrong though -

its pretty expensive regardless, now if someone could find a bulk source for pCPA then one could mix their own and even find their own ratio that might be more beneficial-
 
Call me weird but Pirac is a good sleeping AID for me.... But i have annoyingly good dreams like finding drugs or winning money and then wake up dissapointed.
 
Splatt said:
Call me weird but Pirac is a good sleeping AID for me.... But i have annoyingly good dreams like finding drugs or winning money and then wake up dissapointed.
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Really - how much do you take and in combination with what other drugs-

do you take other recreational drugs too such as MDMA, stimulants, etc-

I have a theory that piracetam only really shines in people who have their diets and exercise on track as well as refrain from abusing any monoamine releasing drugs-
 
Wikipedia's a pretty crappy source to learn about nootropics.


Try the forums on imminst.org.



Green tea was mentioned; DRINK MORE GREEN TEA!!

Theanine, ECGC, a tiny bit of caffeine: It's a seriously neuro-beneficial cocktail ;)
 
My current stack -

Alpha GPC - 1g/d
Piracetam - 4.8g/d
Bacopa - 200 mg 2*/d
Ashwagandha - 900mg/d
Rhodiola Rosea
Ginseng (contains 7 kinds of extracted ginseng ++)

Future Stack (includes cost per month) -

Deprenyl - Selegine - 4.50/month
Aniracetam - UN - 10.00
Vinpocetine - UN - 12.50
Phenibut - UN - 7.30
Alpha-GPC - UN - 15.00
Jarrow Magnesium Optimizer (Magnesium, Potassium, Taurine) - VC - 6.24
NSI Ultra 357 Energy Complex (Siberian Ginseng, Royal Gelly, Gotu Kola) - VC - 8.00
NSI American Ginseng - VC - 2.50
NSI L-Tyrosine - VC - 2.50
NSI Passion Flower - VC - 3.00
NSI B-100 - VC - 1.50
NSI B5 - VC - 1.60
NSI L-Theanine From Suntheanine - VC - 15.54 (2)
NSI Mega EFA Omega-4 EPA & DHA - VC - 5.50
Taurine - VC - 6.90
Bacopa - BN - 3.00

VC - vitacost.com
BN - bulknutrition.com
UN - uniquenutrition.net
 
Also, Ketamine combined with my current stack is very interesting. I seem to able to become very aware of my brain. Awareness is enhanced period.
 
samadhi_smiles said:
Really - how much do you take and in combination with what other drugs-

do you take other recreational drugs too such as MDMA, stimulants, etc-

I have a theory that piracetam only really shines in people who have their diets and exercise on track as well as refrain from abusing any monoamine releasing drugs-
Click to expand...

Not really that often.. every few months, but when I do I go pretty hard

cant say my diet and exercise is exactly on track.

i just find it a bit of an anti depressant/anti anxiety agent atm. normal dose is a gram. Higher doses 2400-5000 make me pretty sleepy and I get a few weird hypanogic visuals or seeing stuff in my peripherial vision.
 
well, piracetam definitely gives me slight crystaline visuals, or rather exacerbates the minor disturbances that are already there-

splatt, I hope you don't find this offensive, but you should really work on your diet and try to figure out some exercise if you really want to see positive effects from your body-mind system-

peace and take care,
S_S
 
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