SKL
Bluelight Crew
- Joined
- Sep 15, 2007
- Messages
- 14,632
To say that the exact same material at random will cause
Trip A: extensive open eye visuals, zero to very little body load
Trip B: no visuals, extreme body load
is also not reasonable. Never happened to me when I had a quantity on hand. Same batch always tended to do pretty much same thing. I cant comprehend where you guys are coming from claiming this. It is very much at odds with my experience, and that of others I know, and does not make pharmacological sense.
You keep saying it over and over but I feel it is an extraordinary claim. Perhaps I have an extraordinary brain that responds in a far higher consistency than yours does, I dunno.
But anyway, good discussion, I feel we are getting down to the nitty-gritty of the "different effects" aspects of the inquiry. Well sort of. Seems difficult to ever really quantify such things when a trip can last for such a long time and contain so many separate "momentary impression units."
Well, I have definitely experienced this sort of variation with tbe exact same material. Less so as regards the bodily effects, but with regards to the sensory and psychological effects the potential for variation is extreme. I've also experienced similar variability with a wide swath of drugs, not all of which are psychedelic. Set, setting, and other intrinsic factors (balances of neurotransmitters, whatever) are enormously powerful in determining the qualitative nature of the experience. The pharmacology of psychedelics and of the ergoloids in particular is hugely complex and interacts in a very subtle manner with an immeasurable number of variables in our brain, and the psychological effects also immeasurably complex and interacting in a very subltle manner with an immeasurable number of variables in our mind, if you will permit, arguendo, my unabashed dualism of brain and mind for the moment.
It is obvious that different drugs have different effects on the mind/brain due to their different pharmacological properties. However, there have been studies done in which subjects were unable to distinguish between LSD and 4-HO-DMT, not to mention the study in which people were given a high or a low dose of LSD and told the opposite, and they tended to react more in the manner of what they were told rather than what they were given. I find this exceedingly hard to believe, I think there are problems with these studies and I'm quite sure I could differentiate between LSD and 4-HO-DMT, but they all go to show that not all the determinants of the psychedelic state are pharmacological.
I think to deny the possibility that psychedelics have potentially hugely variegated effects actually downplays how complex and fascinating they actually are. The pharmacology is infinitely more complex than just metaphorically turning the drug effect on and off like a lightswitch. The possibilities truly are endless.
I would even venture to say that the amount of subjective variability possible between 2 LSD experiences does, in fact, approach or perhaps even exceed the subjective variability between closely related but different drugs. The pharmacology here is incredibly complex and nothing is simple or black and white.
I am very interested in studying subjective differences between psychedelics and this is a large part of what I hope to do with the Esoteric Pharmacology Project; however, I am quite doubtful that in a double blind type setting (such as buying a blotter of unknown provenance off most dealers
