but all of this fades with tolerance. Eventually it will only become an "enhancer", and the effects fade to the background![:\](https://bluelight.org/xf/BL_Images/Orig_Emoji/wrygrin.gif "wry grin :\")
tolerance to the chemical aside, do you think this has more to do with NMDA or a sigma tolerance/change/'damage'?
The Big & Dandy Methoxetamine Thread - Part 13: Don't you know? MXE comes from MXE-co
- Thread starter Solipsis
- Start date
- Status
tolerance to the chemical aside, do you think this has more to do with NMDA or a sigma tolerance/change/'damage'?
vortech
Bluelighter
Whatever damage this drug has done to my brain, I can't comprehend it. Now there's a funny paradox.
I'm about to throw in the towel on an epic week-long run of daily use. Write a retrospective. Let my receptor sites settle back to what can hopefully be considered a 'normal' state.
Folley
Bluelighter
I couldn't really say, this is only based on anecdotal experience as there isn't much research on MXE out there.. I will say it seems rather light on the body even with sustained abuse, but when you stop using it there is some noticeable effects that linger for quite some time.
Really, you shouldn't be using this everyday. I know it's soooo easy to fall into the habit and sooooo hard to break out of it but you lose most of the positive effects after a while and it becomes just another "drug"
nuke
Bluelighter
- Joined
- Nov 7, 2004
- Messages
- 4,191
Does this cause wicked cross tolerance with ketamine too? I did a bunch of K later that day on methoxetamine and never really got to my normal k-space of therapy even after some 100 mg on top of my MXE dose. Today I tried 35 mg ketamine intranasal and didn't really even feel it aside from a little ataxia, and decided that I'd be best off not trying to drive my tolerance up further by using more.
Guess I'll give it at least a month or two.
Guess I'll give it at least a month or two.
psood0nym
Bluelighter
Yes, it causes cross tolerance with ketamine. If you're going to frequently use NMDA antagonists, make those doses on the lighter end is my thinking. Never hit the system hard more than once in a period.
Having tried nasal, sublingual, oral and i.m. administration before I only recently tried plugging for the first time and instantly fell in love with the lubricated syringe up my ass. What a surprisingly pleasant and effective ROA!
phenethylo J
Bluelight Crew
- Joined
- Jul 23, 2010
- Messages
- 4,917
^ yea plugged mxe is simply amazing
Contemplating eating a low dose of mxe before catching my flight tomorrow morning. Not enough to really trip but enough to get that nice opiate-like chilled out feel. Should help pass the time and make the flight more interesting. I'd rather do some K before but the duration is short and I have no intention of trying to sneak drugs past security.
Contemplating eating a low dose of mxe before catching my flight tomorrow morning. Not enough to really trip but enough to get that nice opiate-like chilled out feel. Should help pass the time and make the flight more interesting. I'd rather do some K before but the duration is short and I have no intention of trying to sneak drugs past security.
Last edited:
Yes ? Examples ? Duration ?
dan k
Bluelighter
i enjoyed doing 50-100mgs k and 50-75mgs mxe at the same time both insufflated as neither really hurt, the k kicks in right away and the mxe is coming on nicely once the k is starting to taper off... leaves your face quite numb for a while too
a couple of weeks ago i had possibly a bad reaction with medication(wellbutrin) snorted a line and immediately felt that something was off. started getting jitters that kind of felt like and incoming seizure(ive never had one) and then i thought there was a hole in my sinus cavity and the snot coming out was brain fluid. needless to say the next couple of hours were spent in the bathtub questioning my sanity. i stopped the wellbutrin and have done mxe a couple times since, only im scared of snorting anything now. kinda weird
dezz
Bluelighter
- Joined
- Oct 15, 2011
- Messages
- 1,662
Just had the weirdest crap happen to me. Took my first dose after a few weeks of no MXE, about 40 mg's it was. Was sitting in the living room and suddenly I got a weird feeling of either my mom or dad coming in and since I couldn't be seen in this state I crawled upstairs to my room. Literally 10 seconds later I heard the door open and my parents came home. Not the first time this has happened as well, somehow weird events of synchronicity and deja-vu seem to occur during MXE trips to me, like thoughts and reality become intertwined.
vortech
Bluelighter
It is this phenomenological synchronicity that keeps me so utterly fascinated by (and coming back to) the dissociated headspace.
Mr. Meowfish
Bluelighter
I absolutely agree. For some reason, really cool shit always happens to me when I'm on dissociatives......I know this is completely delusional that disco's would make any difference in what happens in actual reality - but I feel like what happens is, we end up doing things that we normally might not be able to do because you feel so damn relaxed and mellow, but confident oddly at the same time. It's so addicting to me because I've had self admitted low self esteem for a good portion of my life - so it's kind of inticing to do a drug that makes you feel pretty much godlike as quite a few of my friends have described MXE's headspace. I'm sure that sounds super lame and now everyone's like, damn Meowish, I've lost all respect for you and no more cool points will you get........I'm just being retarded and sarcastic now, so I'll sign off. I think I got my point across if there was one. - Meow
psood0nym
Bluelighter
Heh, are you sure that the sound of a car pulling in, or an increase in illumination in the room as their headlights turned into the driveway didn't subconsciously cue you into the fact that they were back, but you were simply too fucked up to recognize anything but a "weird feeling" they were back or remember any different? This is how synchronicities on dissociatives tend to happen. I think there might be some brain lag time involved with our consciously perceiving events on dissociatives, such that we're recognizing what's going on perceptually a little bit ahead of when we recognize what's going on conceptually. This culminates in a sense of presaging what's going to happen next subjectively when it's just that we're too imperceptive due to the drugs to realize what's already happened objectively. After a while this can start to feel like predestination unfolding, and things "being meant" to happen. I'm pretty sure this has happened to me.
That said, I did have what could arguably be called a genuine synchronicity on MXE recently. I had used phenibut with MXE and slept WAY too long. I woke up to "C" from work ringing my phone around 5 p.m. and asking me ...
"Shouldn't you be somewhere?"
... since I had to be in at work that evening and I was nearly late. I said I'd be right there and rushed out and went into work. After finishing the thing I had to do at work that night I figured, since I had slept until 5 p.m., I might as well stay up through the night and the next day on MXE to get back on a normal sleep schedule. When 1 p.m. rolled around the next afternoon, while I was still very dissociated, I grabbed the mail. There was an envelope that contained my new debit card along with a letter listing a local number for my new bank, which I was to call if I had any questions about the card, and I did. I *thought* I dialed the bank's number ...
"Hello"
"Yes, I have a question about my new debit card," and then from the receiver I hear,
"Shouldn't you be somewhere? ... ha ha ha ha!"
It's C, the last person I talked to, who's recognized my voice, and she's fucking with me. It turned out that the new bank's number was one number different than her home phone number that she was talking to me from now, which she had never given me, and my finger happened to slip just right and hit the "9" instead of the "6" to call her at her private residence and hear the same "shouldn't you be somewhere?" question I had heard her asking me from work after waking from my MXE/phenibut coma and picking up the phone at my bedside about 20 hours earlier -- the only other conversation over my phone I had had since.
We had some small talk, I mentioned that her number was one off from my bank's, and I hung up. I laughed while checking my phone's logs, confirming that everything did in fact happen as I thought, and this really wasn't just some dissociative head trip. It would have been a weird synchronicity sober, but it had to happen on fucking MXE.
Last edited:
Watch out when you do too much MXE you turn into Donnie Darko.
dezz
Bluelighter
- Joined
- Oct 15, 2011
- Messages
- 1,662
I know I probably subconsciously heard someone come home or whatever, but still, something interesting always seems to happen the minute I am high on MXE. Especially regarding my friends or other people, I would be bored out of my mind the entire day and upon deciding to take some MXE the minute I am high there would be several invitations to chill by loads of people I never speak to, or those times when the music decides to take an euphoric lift the moment you decide to get up and do something. It's probably in my head but damn it's a pretty cool effect which I haven't gotten from any other drug.
On a rather different note another thing I have noticed which is quite strange is that while under the influence I seem to be more sensitive to nicotine. I'm a pretty heavy smoker and smoke at least a pack a day, but while on MXE cigarettes tend to make me sick and smoking like I normally do tend to make me light-headed and dizzy. Pretty much like someone who has never smoked before. Might make for a really good aid for quitting the damn stuff
On a rather different note another thing I have noticed which is quite strange is that while under the influence I seem to be more sensitive to nicotine. I'm a pretty heavy smoker and smoke at least a pack a day, but while on MXE cigarettes tend to make me sick and smoking like I normally do tend to make me light-headed and dizzy. Pretty much like someone who has never smoked before. Might make for a really good aid for quitting the damn stuff
LucidSDreamr
Bluelighter
the perceptions of a bunch of polydrug using twenty somethings using chinese mxd aren't exactly "scientific research on MXE", not saying the information is useless, but it is a far cry from scientific research.
vortech
Bluelighter
It doesn't have to be that way. A pretty thorough case report can be assembled by a look at my post history. I would encourage all users to post details of their case wherever it may be, whether on the forums or blog posts. That way, if there are serious inquiries being commissioned to research this drug more thoroughly, this site could be used as a valuable pool of user data.
psood0nym
Bluelighter
^I think you're correct essentially, though it depends on how what you're suggesting is conducted, and even assuming one adopts a rigorous methodology the conclusions that can be drawn are extremely limited relative to most observational studies. For a real life example check out the study linked to on page one of this thread: Methoxetamine (MXE) - A Phenomenological Study of Experiences Induced by a 'Legal High' from the Internet.
Never tried this but recently seen a 'substitute' for it advertised on a RC site. Anyone tried this? If I was interested in trying MXE would it be worth getting the substitute? Sorry if this is off-topic or belongs in a thread for the chem I'm talking about.
- Status