The Big & Dandy Methoxetamine Thread - 5th Dose (you took too much, seriously)

[psood0nym]

^From everything I've read producing compounds of only one chirality, or ratios that differ from 50:50, requires extra steps and expense. It's doubtful there is anything but 50:50 MXE out there (if there was it would be MUCH more expensive. I've seen no definitive evidence that any brand of ketmine besides Ketanest S is anything but 50:50, for instance, yet everyone theorizes about ratios to explain perceived differences (if anyone has any evidence to the contrary from a professional manufacturer I'd be interested to see it). This is probably mostly because that's what their dealers tell them to sell whatever brand they happen to have at the time. Unlike any other brand, Ketanest S is explicitly marketed as S by the actual legit company that produces it (not just street dealers) and is substantially more expensive than 50:50, as would be expected.

I've noticed a lot of subjective variation between the same doses of the same batch of MXE, and I attribute that variation entirely to subjective factors, esp. tolerance.

 

[PsychedelicPeptide]

I think the large lines are your problem. It is hard to say precisely what ratio of methox isomers people are getting. One synthesis method could produce an isomer ratio of 20:80 consistently while another could be 50:50, another 5:95. There are a lot of factors, particularly the synthesis scale.

I wouldn't think much about it until someone publishes work definitively showing one is different from another. Scott I think your problems are linked to the high dose rails (and possibly additional excessive use in a short time span?)... it sounds like you could use a few weeks break (at minimum) to help clear your head.

 

[psood0nym]

^I stand corrected, I guess. I heard that all professionally produced ketamine is 50:50 R:S with the exception of Ketanest S (at least as far as is documented). Why else wouldn't companies market there own as being "more S" if it's easy to change the "synthesis scale" to prefer S? Is it more expensive to change the synthesis scale to prefer S over R? In the case that it's really easy and without much more expense why don't companies universally produce the preferred high ratio S ketamine, document it, and market it as such, as in the case of Ketanest S? I had read there are only a few specific techniques required to produce "enantiopure" compounds. If it isn't more expensive (thus maintaining profit rationale), then why not just change this synthesis scale to get 5:95 ratios for compounds where one enantiomer is preferred to get near enantiopure compounds without bothering with the extra expense of the specific techniques listed here?

 

[crOOk]

I think methoxetamine was far stronger and the chirality of the molecule produced and the expression of its effects as one side chilled the other tripping with a manic edge were better back in dec 10 but I have made many a mistake in railing large lines of 150-300mg at once and having blackouts and psychotic/manic style behaviour outbreaks recently.

I think there's been several alterations made on these two sides,know what I mean?

Id like to hear your views

I'm afraid to tell you that there is no punctuation in that first "sentence" and that I can't quite figure out what you're trying to say. Something about vhirality... Are you saying that a new product is just a single isomer compared to an old product you had. Maybe just lay the dust off for a while and hopefully you'll feel better soon. Dissociatives are infamous for their property to induce a psychosis in some individuals. One of my friend went bonkers after using DXM for a consecutive 3 days and after several attempts to end his misery (in one case with feces and a naked robbery involved), he now gets depot injections of neuroleptics. He surely was very much prone to schizophrenia before (I told him over and over not to do any psychedelics or exactly that would happen), but there's no question that the combination of sleep deprivation and DXM caused his first episode along with a a few psycho-social factors.

I sincerely hope that you'll be fine after some time has passed by, but if your "psychotic/manic style behaviour" persists it might be a good to see a good idea to see a psychiatrist to avoid any serious consequences.

first time last night. give it a 6/10. Still much prefer k.

I really enjoyed small doses, nice and euphoric, with a weightless feel to it. But when I racked up a fat line and got into bed hoping to hole, I had a pretty awful experience where I was convinced for a while that the stuff I had bought was very toxic and I was going to die. Never felt like that on k. I also couldn't get to sleep for hours afterwards; it was like the main strip in Las Vegas had relocated to my mind. The red standby light on my cd player looked like a burning ember...tried to put it out. It's weird stuff, kinda has a nasty side to it though.

That sounds a lot like my first pcp experience. I got that to change by switching from intranasal administration to smokin dat shit! I've often thought I'm only using pcp for it's euphoric/manic afterglow on one hand and to get relief from the same (exhausting) afterglow on the other hand.

that is always the main theme of my k-holes.

Same here.

 

[crOOk]

^I stand corrected, I guess. I heard that all professionally produced ketamine is 50:50 R:S with the exception of Ketanest S (at least as far as is documented). Why else wouldn't companies market there own as being "more S" if it's easy to change the "synthesis scale" to prefer S? Is it more expensive to change the synthesis scale to prefer S over R? In the case that it's really easy and without much more expense why don't companies universally produce the preferred high ratio S ketamine, document it, and market it as such, as in the case of Ketanest S? I had read there are only a few specific techniques required to produce "enantiopure" compounds. If it isn't more expensive (thus maintaining profit rationale), then why not just change this synthesis scale to get 5:95 ratios for compounds where one enantiomer is preferred to get near enantiopure compounds without bothering with the extra expense of the specific techniques listed here?

Well one reason could be because we don't give a shit if our dog has a weird dream during anaesthesia. :D No seriously, from what I know it is more expensive and I thought they separated the enantiomers after synthesis of racemic ketamine. Might be entirely mistaken there though, you'd have to do more reading or hope for someone else to know more about ketamine synthesis.

 

[Xamkou]

If it doesn't arrive today I'm going to be so gutted.

edit: omfgg hereerere

 

[scottishdnb]

Thank you both for your feedback. I have had a 3 month break from methoxetamine until now, so I cant really attribute my experiences to a building of tolerance I dont think. I have had batches where I could tell a cutting agent was present, and these yielded very mild results.

I think that, when eated, the chemical tends to produce more sustained release with less of a sharp come up maybe making the manic effects less pronounced or at least a bit slower and gentler.

I have not encountered any CEVs and true M holing since the early batches.

Is it possible that repeated use has damaged the receptors in my brain?

 

[Tromps]

Can anyone explain their best possible accurate description of what effects are felt while experiencing an m-hole? I have done some pretty high doses and have felt some incredible things, but I'm not sure as to whether it was the true hole or not.

 

[Disco Doctor]

HOLEE SHEET! I have been taking this for around eight months, always in lowish doses. A 40mg bump is incredible for playing Grand Theft Auto IV - you get so immersed in Liberty City I can spend half an hour "talking" to a guy selling hotdogs on the side of the road. Smaller, 25mg bumps are amazing for gigs or pub nights, and about 35mg is amazing for watching movies at home.

But the other night, I finally approached what many call the M Hole. I snorted 50mg, followed within an hour by two more doses of 20mg. I still have trouble describing what I experienced. I was lying on my bed listening to my iPod - I set up a few tracks like Pink Floyd and Led Zeppelin that I thought would work well. At first I felt like massive hands were pushing me from all sides on my bed, then I was overwhelmed by massive pulses of ecstasy. My whole body was vibrating with pleasure - it was amazing! Then I couldn't feel my body any more and sort of sunk into my bed, away from my body and into an ether of subconscious that was somehow mixed into the music. It was utterly bizarre but amazing. It only lasted about 30 mins, but I remember getting up afterwards panting like mad, looking at myself in the mirror saying, 'Fuck me!'

It made me realise I had just been scratching the surface of this substance and I can't wait for another opportunity to delve deep. I know low doses are amazing, but if you are like I used to be - a bit apprehensive about caning it - I would say go for it as it's one of the best experiences I've ever had.

 

[Albion]

HOLEE SHEET! I have been taking this for around eight months, always in lowish doses. A 40mg bump is incredible for playing Grand Theft Auto IV - you get so immersed in Liberty City I can spend half an hour "talking" to a guy selling hotdogs on the side of the road. Smaller, 25mg bumps are amazing for gigs or pub nights, and about 35mg is amazing for watching movies at home.

But the other night, I finally approached what many call the M Hole. I snorted 50mg, followed within an hour by two more doses of 20mg. I still have trouble describing what I experienced. I was lying on my bed listening to my iPod - I set up a few tracks like Pink Floyd and Led Zeppelin that I thought would work well. At first I felt like massive hands were pushing me from all sides on my bed, then I was overwhelmed by massive pulses of ecstasy. My whole body was vibrating with pleasure - it was amazing! Then I couldn't feel my body any more and sort of sunk into my bed, away from my body and into an ether of subconscious that was somehow mixed into the music. It was utterly bizarre but amazing. It only lasted about 30 mins, but I remember getting up afterwards panting like mad, looking at myself in the mirror saying, 'Fuck me!'

It made me realise I had just been scratching the surface of this substance and I can't wait for another opportunity to delve deep. I know low doses are amazing, but if you are like I used to be - a bit apprehensive about caning it - I would say go for it as it's one of the best experiences I've ever had.

Love that first time crossing the MXE border. You really feel as though you have stumbled across some kind of hidden treasure. Enjoy exploring the world of MXE

 

[Ds]

this shits great if you IM it! i hardly put any in the spoon, and use roughly 5cc of water if even that much. do it the same way at the doctor office thru the buttcheeks. gives me enough time to rinse the rig, and the feeling is over whelming so i crash on the bed and just lay there with music on.

 

[Mongrel]

Just picked some up yesterday. I've only done K twice now, but the impression of the expierence is still with me. Thinking about doing 30-40mgs soon. My connect said sublingual administration is better than insuffulation, anybody got any input here? I'm thinking I'm just gonna blow it, not too sure how wasteful that may be.

EDIT: Too late now. Just bumped that shit.

 

[the toad]

This last batch of mxe I got keeps me awake for 12 hours... idk wtf is up... for the past 4 months or whatever I've been able to take sme at say 6 or 7pm and hadno problem falling asleep by midnight or so... but the last couple times I've taken it in the evening, I haven't been able to fall asleep until like 5am...

The rest of the effects seem the same as they've always been except for that...

I'm a bit puzzled...

This only happenened since I've got this new batch... basicly it seems to have about double the duration of the rest...

 

[PsychedelicPeptide]

^I stand corrected, I guess. I heard that all professionally produced ketamine is 50:50 R:S with the exception of Ketanest S (at least as far as is documented). Why else wouldn't companies market there own as being "more S" if it's easy to change the "synthesis scale" to prefer S? Is it more expensive to change the synthesis scale to prefer S over R? In the case that it's really easy and without much more expense why don't companies universally produce the preferred high ratio S ketamine, document it, and market it as such, as in the case of Ketanest S? I had read there are only a few specific techniques required to produce "enantiopure" compounds. If it isn't more expensive (thus maintaining profit rationale), then why not just change this synthesis scale to get 5:95 ratios for compounds where one enantiomer is preferred to get near enantiopure compounds without bothering with the extra expense of the specific techniques listed here?

Oh I think you misread what I meant with the synthesis scale part. The actual synthesis procedure is what is going to control the ratio to the greatest extent. So your 50:50, 20:80 and 5:95 ratios would be easiest to obtain by changing the chemical reactions and conditions that produce the drug material.

The effect of scale probably isn't going to be that great, but could shift you from 50:50 at say 100 grams to 40:60 at 1,000 grams to 30:70 at 10,000 grams (10 kilos). Recognize things like moisture in the air can even change some reactions if they are done in open air, so your 10 kilo synthesis might be 30:70 one day and 40:60 the next.

So it is in no way easy to change the scale to get one isomer over the other, unless your particular drug has an extremely predictable and consistent tendency to do this (it is highly doubtful people could reliably do this but there are always exceptions to these sorts of things).

But if the exact ratio is indeed relevant to the biological activity, then your 50:50 mix and 30:70 mix are going to feel a bit different. How much that would be is certainly debatable but we just don't know much about it at this point.

Ketanest S, if it is more expensive, is probably because it is a greater purity of S. I don't know much about it personally though. If Ketanest S is a registered medical drug, then I see no reason to believe it is anything but what they say it is. If users don't report a slightly different high when it is supposed to be different, then perhaps the subjective differences between isomers is not as great as what is thought.

 

[ColtDan]

But the other night, I finally approached what many call the M Hole. I snorted 50mg, followed within an hour by two more doses of 20mg. I still have trouble describing what I experienced. I was lying on my bed listening to my iPod - I set up a few tracks like Pink Floyd and Led Zeppelin that I thought would work well. At first I felt like massive hands were pushing me from all sides on my bed, then I was overwhelmed by massive pulses of ecstasy. My whole body was vibrating with pleasure - it was amazing! Then I couldn't feel my body any more and sort of sunk into my bed, away from my body and into an ether of subconscious that was somehow mixed into the music. It was utterly bizarre but amazing. It only lasted about 30 mins, but I remember getting up afterwards panting like mad, looking at myself in the mirror saying, 'Fuck me!'

It made me realise I had just been scratching the surface of this substance and I can't wait for another opportunity to delve deep. I know low doses are amazing, but if you are like I used to be - a bit apprehensive about caning it - I would say go for it as it's one of the best experiences I've ever had.

amazing isnt it, ive felt that before. m-holed into a kitchen floor, completely dissolved into everything. its fucking awesome. pure euphoric love

 

[Mongrel]

This is a very nice dissociation, hit me way harder than I was expecting though

EDIT: Beautiful. I'm in love.

 

[jargs]

Hey people, was just wondering if anyone else gets this effect when fucked on a lot of MXE.

Try spinning round in a circle about 20 times in one direction and then come to a sudden halt. You should notice that your brain thinks you a still spinning round and the eyes will keep juttering to the side even though you have physically stopped moving. Says something about how this drug effects your motor. very weird.

 

[ColtDan]

yeah, reminds me of when im drunk

 

[psood0nym]

Oh I think you misread what I meant with the synthesis scale part. The actual synthesis procedure is what is going to control the ratio to the greatest extent. So your 50:50, 20:80 and 5:95 ratios would be easiest to obtain by changing the chemical reactions and conditions that produce the drug material.

The effect of scale probably isn't going to be that great, but could shift you from 50:50 at say 100 grams to 40:60 at 1,000 grams to 30:70 at 10,000 grams (10 kilos). Recognize things like moisture in the air can even change some reactions if they are done in open air, so your 10 kilo synthesis might be 30:70 one day and 40:60 the next.

So it is in no way easy to change the scale to get one isomer over the other, unless your particular drug has an extremely predictable and consistent tendency to do this (it is highly doubtful people could reliably do this but there are always exceptions to these sorts of things).

But if the exact ratio is indeed relevant to the biological activity, then your 50:50 mix and 30:70 mix are going to feel a bit different. How much that would be is certainly debatable but we just don't know much about it at this point.

Ketanest S, if it is more expensive, is probably because it is a greater purity of S. I don't know much about it personally though. If Ketanest S is a registered medical drug, then I see no reason to believe it is anything but what they say it is. If users don't report a slightly different high when it is supposed to be different, then perhaps the subjective differences between isomers is not as great as what is thought.

I see, now. The proportion isn't necessarily predictable. Thank you for the clarification.

 

[the toad]

You get great ideas on this stuff... but then when you try to do it your all confused and can't figure it out...

Very much like being shitfaced...

Last night I thought "I'm going to set up some speakers and an amp in the garage to hook my ipod to so ill have some music out there...

I got the stuff together but then was all confused as to how I was going to make it all work... and its simple stuff really... I've done iit tons of times before but it just wasn't making sense then lol