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☛ Official ☚ The Big & Dandy DOC Thread - Third opinion

Yes.
I am glad to have found an alternative to test and share anyone I deem knowledgable, and now that I know it works, I'm set.
I'm about 1hr30 in and will be content sitting here smoking and chilling to music for as many hours as it takes. I will submit a full report tomorrow.
Yea except for the residual stimulation leaves you up for hours after!!! Lol there is no magic with this one just euphoria the first time you take it. And thoughts get pretty fucking weird very looping thoughts . Visual effects and design frame rate etc is superb though acid Esq. visuals just no magic. And no sleep meh.... I will stick with 4 ho/aco met I find that much superior. Though doc is great with ecstasy. Happy holidays and research drew.

Yep. I've been going since 130 a.m. and I still have leftover stimulation and euphoria 21 hrs in!! Still think there's magic here. Just not for the light hearted, very long. Heh
 
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Was insufflation of this found to shorten duration at all? Or shorten comedown? Depending upon tomorrow's weather, I'll be giving it a shot tomorrow and don't want tobeup all night. If i drop orallyaround four AM, I should be able to sleep by nine at night, right?
 
Is that 18h hours from ingestion or 18 hours after the peak effects are gone? I've done this before, but it seems the more I take it, the more excessive the comedown is. Also, some of those erowid charts just read oddly
 
Yea I would say 18 hours after insulffaing it you should deff have some problems sleeping. If you n have some benzodiazepines they help but you need at least I need 3 to 4 times what i usually take to get b any b help n from the bbenzo otherwise doc cuts right through it. That's always been my experience.
 
Yeah DOC cuts right through most things... I haven't found that benzos really help a lot, I mean they relax you a bit but you'll still be awake most likely. The only thing that will do it is a lot of alcohol... I can drink way more on DOC and I actually really enjoy getting drunk on the tail end of the experience because it's WAY more euphoric and pleasurable than alcohol usually is... if you drink enough you can pass out earlier than you normally would.
 
As Xorkoth can attest to, I'm a DOC handheld and my typical dose is 12-16mg insufflated when I'm trying to break through with DOC. What would a reasonable IV dose be in order to reach that beautiful 16 hourl glimpse of nirvana? I am curious what the IV administration can bring but I refuse to waste invaluable material to low dose sessions. Perhaps 8-10mg could do the trick?
 
12-16mg??!?!? I presume 'handheld' = autocorrect for 'hardhead'? hahaha


But still...12-16mg?!!?!?
 
I didn't try DOC (have some, but still have not enough courage/time/desire for trying it), but I can say about IMing DOI -- I would say 4-5 mg oral = 3-3.5 mg intramuscular (can't say about insufflated doses, don't like it). I think for intravenous will be almost the same ratio. Take in account that when I did DOI I did it really often, sometimes up to three times in a week. That was years ago. If I will try to do it now I will go lower.

I think you estimate right about 8-10 mg. But I still suggest to go lowest (8 mg) and keep in mind that IVing can have some unexpected sides -- even comparing to IMing, so you can possibly meet some issues I never felt or heard about. Don't trip alone and be safe.

I hope someone experienced with IVing will add some information. Anyway try to look in this or previous threads. I am almost sure someone already asked or said about IV.
 
Sorry, it was a while ago (and by while I mean not only time passed but all other substances I tried since that :)) so I don't remember details. As you probably expect IMing decreases time of come-up and total time of trip but not really much, maybe for only few hours. If I could go to sleep without other drugs or alcohol after 16-18 hours (depends on dose obviously -- once I ate 7-8 mg and tripped for 40 hours), with IMing I can go to sleep after 14-16 hours. Faster come-up means it is a bit rougher. But since I liked feelings how I became more and more high it was rather benefit than disadvantage. Overall trip is the same...
Ah, if I remember right stomach discomfort is somehow lesser. This was the same for 2C-E too, tried once to IMing it. I was afraid that I will puke on come-up but suddenly it was very smooth.
 
It's possible that via IV DOC would react in unexpected ways... for example I have heard many reports of people IVing very low doses of 2C-E, even like 2mg, and having very uncomfortable chest pains and so forth and reporting that it felt very unsafe. I have no idea if DOC would react like this - I have never read a report of IV DOC - but I think it's best to try it at a much lower dose once first to make sure. And then raise it if it goes well. You can't un-IV something once you've done it.
 
Can i use plum brandy 40% alc as a solution or do i need anything stronger for storage for two years?
Thanks.
 
tripping for 30+ hours?

what on the world is this stuff really out there???

and you can get it via RC companies online?
 
isnt this the chemical some dude died on. i totally thought there was some phenylalanine resembling 25c-nbome they recently proved could cause toxicological fatalities.

yeah definitely was doc i saw the article about. heres the article
PubMed said:
A fatal intoxication of 2,5-dimethoxy-4-chloroamphetamine: a case report†.
Authors
Barnett , Baker , Kelly , McGuire , Fassette , Gorniak .

J Analytical Toxicology. 2014 Oct;38 (8 ):589-91. doi: 10.1093/jat/bku087.

Designer drugs appear to be increasing in popularity because of the ease of obtaining these constituents, the lack of ability to identify the substance(s) in routine drug screening, the appeal of the drug(s) being 'safe' due to them being marketed as a 'legal high' and possibly due to stronger restrictions that are being placed on prescription drugs. As components of designer drugs are identified and regulated by the DEA, new constituents, or analogs, of these designer drugs are being manufactured to circumvent legislation. 2,5-Dimethoxy-4-chloroamphetamine (DOC) is a substituted alpha-methylated phenethylamine and acts as a selective serotonin receptor partial agonist. There is limited literature on this particular compound and no literature that attributes death to use of this drug alone. We present a case of a 37-year-old male found at home lying face down next to a book titled 'Psychedelic Chemistry' by Michael Valentine Smith and in the early stages of decomposition. The decedent was a known methamphetamine abuser. A peripheral blood sample collected at autopsy was sent to toxicology for routine analysis. Results yielded negative for the drugs of abuse classes on the enzyme-linked immunosorbent assay screen but was positive for DOC during routine GC-MS analysis. A urine sample collected at autopsy was subjected to a routine urine liquid/liquid analysis via GC-MS, and the specimen was positive for DOC. Quantification analyses showed DOC concentration levels to be 377 ng/mL in iliac blood; 3,193 ng/mL in urine; 3,143 ng/g in liver and 683 ng/g in brain. DOC was not detected in the gastric contents. Caffeine was the only other compound detected in blood and urine. Due to the lack of literature, we believe that this is the first case where death can be attributed to DOC alone.
 
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isnt this the chemical some dude died on. i totally thought there was some phenylalanine resembling 25c-nbome they recently proved could cause toxicological fatalities.

yeah definitely was doc i saw the article about. heres the article

Well, to be accurate, DOC is a phenethylamine--and an alpha-methylphenethylamine (or, amphetamine) to be precise--not a "phenylalanine" (which is an amino acid, albeit structurally related to phenethylamine), and it only resembles 25C-NBOMe (which, if I'm not mistaken, is part of a novel class of N-substituted dicyclic phenethylamines) in the most tangential fashion. In other words, not really at all.

Which is just to say that a single report of a fatality associated with DOC (note that the report mentions the body was already decomposing when they found him) without any indication of what particular organ/system failure and/or pre-existing condition he may have suffered is hardly the kiss of death for this compound, nor does it "prove" that DOC was responsible for his death or that it can "cause toxicological fatalities."

Basically, they found a decomposing body (lying next to a copy of "Psychedlic Chemistry") and simply because he had DOC in his system when he died they are assuming it killed him. That's a fucking big assumption, especially considering DOC's track record in 40+ years of human experimentation with no other death. Not to say it couldn't happen--maybe it did--but relative to many commonly ingested psychoactive compounds, DOC is pretty solid.

Quite a different story when we are talking about the unpredictable and (in my view) excessively dangerous and potential fatal NBOMe class of compounds you compared it to. Just wanted to point out that there really is a world of difference, pharmacologically and even physiologically, between the structures and actions of DOC and 25C-NBOMe, and it's best not to ever confuse the two.

Nonetheless, it was very good of you to post the abstract--the more info we can all draw on for HR purposes, the better--so thanks for that.

Cheers!
 
I'm quite positive that DOC killed that man. It does not have the safety record that some of the safer RCs do. It's killed a few other people as well. Let's not be silly about this.

That being said, nbomes are far more dangerous. DOx compounds are reasonably safe as long as you dose properly--its in overdose that they become dangerous. Nbomes are known to kill even at normal doses, and even at doses that the user has previously taken without issue.
 
InterestingFACT,

I'm in complete agreement with you on all of the points above, except for the certainty. It is not clear how DOC killed that man, if indeed it was exclusively responsible.

Nonetheless, you are right that DOC (along with others in the DOX series) can be fatal when consumed in overdosage quantities; however, the relative margin of safety--even up to a full magnitude of value higher than typical doses--is considerable, even by RC standards (lysergamides and 4-subs aside).

Again, as you say, NBOMes are a whole other crap shoot, and can't really be compared with any other widely consumed class of psychedelics due to their apparent (and still largely unknown) health risks--even at normal doses, as you correctly point out.
 
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