Hey so thought id contribute... read most of the posts to this topic
I'm diagnosed bi-polar and have done a pretty large variety of psychedelics, as well as things like MDMA.
MDMA I would say being bipolar is the worst idea on the planet atleast for me. The comedown is just downright frightening.
As for tripping...
On ups I would say with me it varies alot from experience to experience and also what substance is being used. Anytime i start out in anyway edgey or "prickly", as my girlfriend puts it, is generally a bad idea because sometime during the trip itll lead to a pretty bad emotional crash. But that pretty much comes down to controlling the environment and not messing around with stuff when shit is going on in my life. Also depending on the trip it can have a much later impact after the trip to my emotions if i get something in my head and brood on it.
An example of an experience that was on an up where i made some mistakes and didnt care for my own limits...
Earlier this summer after a night at summerfest me and a friend took some 2c-b. That night i had run into someone who has a pretty negative influence on my life, so I was in kind of an underlying dark mood starting off even though i was more upbeat and not thinking about it when i took it. That night went really well sat around telling some really dark jokes as the floor was caving in underneath us...
Where the mistake was is that the following night on about 3 hours of sleep dosed again only this time a hit of lsd and a half of the 2c-b i took the night before. My reasoning, I had tripped without my girlfriend who was going to be tripping for the first time that night, and i wanted to experience that with her. For most of the night it was an extremely pleasant experience, my girlfriend was tripping for the first time, one of my closest friends there to talk with, falling into a strong sense of egodeath(which was unsettling at first) but an overall positive experience. The next morning ,however, after all the visual bells and whistles had gone and it had become mostly mental things got ugly. I started to brood and feel selfconscious about the previous night and basically tripping over being upset over seeing someone. From there my thoughts just started spiraling out of control about my entire life, and I just had a complete emotional breakdown. I was lucky in that I had people there to try to comfort me because i honestly dont know how i would have handled it if I were alone.
On downs......................its just an entirely entirely bad idea. Ive gone as far as being suicidal after the dumb mistake of tripping on a down, which i hope never to make again.
all on occasion it seems to make my swings take a more rapid pace which normally seems to be like 1 to 4 weeks and takes it down to a week or less which is really confusing.
For all I've written it basically comes down to, overall, in being the bipolar person even without psychedelics your mind can race around and dig into deep dark holes, and you have to remember that psychedelics do that to so its just gunna increase that factor in your mind, which can lead to both good and bad things.
well hope I atleast gave a small amount of insight.