Anything less than 100 mg is missing the true nature of this one in my experience. Between 100 mg and 200 mg the experience has been very nice, lots of chest glow love for humanity feelings, soupy warm headspace, and great body buzz...very sexual feeling ala 5-MeO-DiPT, or 4-HO-DiPT, but better. Insufflation works, but seems to have a delay in the effect manifesting. I found it to be the least interesting roa. Smoking works great 50-100mg, although it tastes pretty bad. I need to spit out each time. The effect is great. However, twice I have had a weird, slightly alarming experience with the material at higher doses. Once while smoking repeated 50 mg doses, and the other time when consuming orally 200 mg and then insufflating 150 mg. On both occasions I became very weak in the knees, quite wobbly feeling, a bit strobey vision, and something very similar to the robowalk from dxm. I was also feeling nearly dissociated from my self at that dosage level, but I did have an amazingly orgasmic chest and body rush, although the overall speediness that accompanied it was a bit difficult to settle into. I wouldn't repeat those higher dosages, but between 100-200 mg is perfect. Very short duration, maybe 2 hours before I was back to being good enough to drive/function in general. It was perfect for attending this wacky bizarrro Animal Collective performance at the Guggenheim the other night. Smoking some green definitely potentiates the effects as well. Have not tried with alcohol.