Personally, with 2c-e, I find its best to eat well the day before or maybe several hours before the trip, dose on a mostly or completely empty stomach, and then start snacking on easy to digest foods at around the peak of the trip. Now when you're my age (44, since we're talking about age), you either accept that your going to be a fat old man who doesn't live that long or you learn to live on just 3 light balanced meals per day. And its since it takes me about 4 hours to pass each meal through the stomach, that means that 12 hours out of the day my stomach is empty anyways. So its not that hard for me to schedule the 4 hour 2c-e come up and my meals such that my tummy is empty during the 4 hour period. And food deeper in my GI tract, as long as its
healthy food, doesn't seem to bother me on 2c-e. A little bit of cannabis always helps too, if you don't mind the buzz.
As for body load being psychosomatic, life is psychosomatic. Throughout your life, your psychic equilibrium affects your somatic equilibrium and your somatic equilibrium affects your psychic equilibrium. Generally, when I take a psychedelic, its going to bring about psychic disequilibrium, which appears as questions in my mind. In response to that I need to let go and let the questions work out and come back to psychic equilibrium, i.e answer the questions in my mind. Usually the result is a deeper state of psychic equilibrium, because of the depth the questioning. But alternatively, I can suppress the questioning, i.e. suppress the psychic disequilibrium. And thats when the somatic disequilibrium, a.k.a. 'body load' starts to manifest, while at the same time my mind becomes dull, more preoccupied with the body problems.
Now I have to have a set, setting and dosage suitable for the level of and type questioning desired, i.e. not be to overwhelmed by unwanted real world stresses at the time. IOW I need to be in some sort of equilibrium, physically and emotionally, with my immediate environment, or that alone will disturb my psychic equilibrium or somatic equilibrium.
On my better 2c-e trips, I've had no nausea at all. Most of the time, I get a little bit of nausea. On one 2c-e trip, I got a lot of body load, mainly nervous energy spikes in my extremities, and I still don't know what it was all about, i.e. why my frame of mind was messed up.
Plus, denying your body of food during a time of stress doesn't seem like the healthiest possible action.
Well, in general, it really depends on the nature of the stress. You don't eat when you have a stomach virus, do you? There's a reason they don't want you to eat before and after various or other medical procedures. If there is a stress is directly on your digestive tract, it may be better to let your digestive system its self rest while you are under the stress. Losing a few meals doesn't kill you. Your body can tap into energy reserves, especially when under stress.