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Phenethylamines The Big & Dandy 2C-D Thread - Please Insert Second Disc

@xdrc wow interesting, where are those notes from? Dr. D Grandstaff reports 80 sessions with 20 patients 35-100/120mg doses, I bet they would have some interesting commentary.. and those 200 and 250mg doses .. wow
 
These notes are from Pharmacology Notebook #7 (https://www.erowid.org/library/books_online/shulgin_labbooks/), p. 809. Isomerdesign attempts to reference to notebook pages, but these evidently haven't been indexed (yet?), see: https://isomerdesign.com/pihkal/explore/23 under "Notebook Pages" (to not find this one).

I have stitched together the available notebooks for personal use, allowing full text search and go diving for nuggets here and there. I have once asked Wendy Tucker if the remaining notebooks are still to be scanned, and I think they have been, but apparently there were issues with people selling the versions shared by Erowid as prints, stealing the hard work. From what I remember she said these one will only be able to read on the Farm. Maybe some day I'll make it to Mecca, but for now a trip to America is off the table.

Regarding Schlichting, I've wrote about this here:
Where do you have the information that those dosages induced full ego loss? They certainly described ego-weakening, but full? Leuner also worked with 4-HO-DET and 4-PO-DET. I think the choice for 2C-D was much more one of practicality and legality. They did not really publish anything (other than just now, "Psycholytische Therapie nach Hanscarl Leuner", Passie, Schlichting, Bolle, Nachtschatten Verlag) and they tried their best to obfuscate the actual compound at the time, hoping for it to evade popularity and as such bans.
I do have the book and am in the process of transcribing the chapter on LE-25 for translation (it's been a while since I read that chapter fully), I may add some more commentary later. Perhaps I can reach out again to ask if the translated version can be shared. In the book Schlichting only mentions his personal experimentation in range 30 - 90 mg prior to the study.
 
I have been taking 2cd 1x a week at 4-7mg. 4mg is the lowest amount i get any percievable effect. I took 3mg today, and dont notice anything.

Even tho i am quite sensitive to pretty much every 2c, i was surprised i could feel 2cd at 4mg (mainly color brightening and a subtle shift in thought processes. My preferred microdose* is actually 7.5mg.

Also i want to report, i combo'd 2cd and MDMA the other night.

It was fantastic. I stacked the peaks, taking 21-25mg of 2cd waiting 40 min, then 75mg of MDMA. Even at what i consider low doses of each, i rolled a lot harder than i would have on the MDMA alone.

I do wish id followed the shulgin route. Meaning MDMA then the 2CD 3 hrs later. but it didnt work out that way. Next time :)
 
I have been taking 2cd 1x a week at 4-7mg. 4mg is the lowest amount i get any percievable effect. I took 3mg today, and dont notice anything.

Even tho i am quite sensitive to pretty much every 2c, i was surprised i could feel 2cd at 4mg (mainly color brightening and a subtle shift in thought processes. My preferred microdose* is actually 7.5mg.

Also i want to report, i combo'd 2cd and MDMA the other night.

It was fantastic. I stacked the peaks, taking 21-25mg of 2cd waiting 40 min, then 75mg of MDMA. Even at what i consider low doses of each, i rolled a lot harder than i would have on the MDMA alone.

I do wish id followed the shulgin route. Meaning MDMA then the 2CD 3 hrs later. but it didnt work out that way. Next time :)
Interesting, how long do the effects of 4 - 7mg last for you? And do you feel its cognitively improving or does it get a little hindering with the serotonergic and psychedelic activity?

I wonder if 10mg 2C-D would be akin to an instant antidepressant 🤔
 
I finally got around to combining 2CD and 2CB and results were pretty much as expected.


Would I do it again? Maybe.. It could prolly be cool at an night time outdoor rave/concert.
 
Interesting, how long do the effects of 4 - 7mg last for you? And do you feel its cognitively improving or does it get a little hindering with the serotonergic and psychedelic activity?

I wonder if 10mg 2C-D would be akin to an instant antidepressant 🤔
Generally lower dosages are shorter in duration. So 5 hrs im coming out. My high dose 79mg, was surprisingly long. 8 or 9 hrs.

10mg certainly brightens up my day tho I don't really know if the effect is antidepressent. I'm generally more positive though, but not ALWAYS. Sry I must've missed your earlier reply, just getting to it now.

ive mentioned this before in this thread, but my 1st experience was 25mg insufflated at the grand canyon. I immediately felt depressed and like a worthless speck of dust in comparison to witnessing something millions of years old. That settled out. 2C-D while I have largely had very positive experiences with, I'm going to call it pretty neutral. And like a lot of psychedelics it makes me feel MORE of what I'm feeling..
 
I second that notion that dosage is a big factor in duration for 2C-D. For me 10-30 mg are typically in the range 3-4 h versus 50 mg having a duration of 5-5.5h about. I seem to metabolise phenethylamines relatively quickly in general.
 
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