The Big & Dandy 25C-NBOMe Thread (part 2) ver. "My skin feels like lightning"

[DylanG204]

hu

I have the opportunity to sample 25C-NBOMe and 25D-NBOMe, but I am opting for the 25D instead based on previous experience that I've had with DOC. Loved the experience --supernova energy with ultra fine resolution visuals, but days after my whole body would feel tingly (the tingly you get when your foot falls asleep) so it wasn't worth it. I only dosed moderately on DOC too, 4mgs tops and never in combo, and have explored DOB at higher dose ranges and not had similar issues.

Having experience with 2c-b/e/i/p and DOB, my conclusion was that my body has an idiosyncratic reaction to chlorinated compounds and while the TRs I've seen of this one make it seem appealing and there's more bang for your buck than with 25D, even the title of this thread "my skin feels like lightning" perhaps suggests that my body reaction to chlorinated compounds isn't so unique...Does anyone have experience with DOC or 2c-C that they could compare the tactile? I really would like to experience this compound, but not at the expense of my body going painfully numb for days on end afterwards.

YES i have just recentley tried 25c nbome after having many succesfull trips with 25I.]

my body also reacts negativitly with clorinated products . THIS IS the first one i have tried however.

 

[ThrowawayAus]

I received 30mg and thought I would dissolve it in a large amount so that I could use a measuring cup for each dose, but now I'm seeing that apparently sublingual is a less effective dosage method. I have 30mg dissolved in 300mL (so that 10mL is 1000ug), is there any way for me to reduce the volume of this solution without getting rid of any substance? I tried 500ug and it was pretty underwhelming. Has anyone tried rectal yet?

 

[JBrandon]

I received 30mg and thought I would dissolve it in a large amount so that I could use a measuring cup for each dose, but now I'm seeing that apparently sublingual is a less effective dosage method. I have 30mg dissolved in 300mL (so that 10mL is 1000ug), is there any way for me to reduce the volume of this solution without getting rid of any substance? I tried 500ug and it was pretty underwhelming. Has anyone tried rectal yet?

Rectal 25I was incredible. I am going to try rectal 25C at some point, but just be aware the potency may be significantly increased.

 

[ThrowawayAus]

I received 30mg and thought I would dissolve it in a large amount so that I could use a measuring cup for each dose, but now I'm seeing that apparently sublingual is a less effective dosage method. I have 30mg dissolved in 300mL (so that 10mL is 1000ug), is there any way for me to reduce the volume of this solution without getting rid of any substance? I tried 500ug and it was pretty underwhelming. Has anyone tried rectal yet?

I was impatient and decided to dose 1000ug in the morning to see if it was any stronger and I think tolerance definitely picks up quickly, this dose actually felt like less than the previous nights dose. I was trying to get a feel for potency since I'm planning on tripping this weekend with friends, all doing it sublingually. How much tolerance would I have in about a weeks time? I plan on having a stronger experience than my trip last night, so I was thinking of aiming for a 1mg level experience, but with tolerance how much would this actually work out to be? 1.2 or closer to 1.5mg? Or should I really just dose 1000mg and hope for the best? I might just do this.

I think part of my lacklustre experience is my psychiatric medication I am on, they are antagonists for 5HT2A and B. I am thinking a week off these will also increase the potency of the experience somewhat, even though they will not be out of my system completely their levels will have significantly dropped.

Any experiences with tolerance here? How long does it take to dissipate and how strong is it really?

 

[JBrandon]

Throwawayaus, if you are on an antidepressant, antipsychotic, or any other kind of mood stabilizing medication you're going.to have all your trips reduced and altered.

 

[ThrowawayAus]

I dosed 1mg rectally, waited 10 minutes, felt it could be a bit stronger so I added another 500mcg. Finally some good visuals with this substance, before this point it had been mostly just distortions but now i'm getting lots of fractal imagery playing itself out across my walls. The emotional side is pleasant and calm, but I wouldn't call it euphoric. Nice though. As far as a mental trip though this substance doesn't really have much going on at all. Pretty colours though, and the musical enhancement is nice. The visuals on this trip were a good bit stronger than 2 hits of strong acid, though that only lasted for the first 2 hours after which it faded to very faint fractals and then just distortions again. The visuals on this don't really compare to the visuals of 2c-e, mushrooms or 4-aco-dmt though, sadly. No physical side effects noted, a bit of giddy stimulation and I wouldn't be surprised if my HR was slightly elevated but nothing to worry about. I dosed at 9.15 and all the visuals are gone by about 1.30am. I wish this substance lasted a bit longer.
Going to try 2mg orally on the weekend to see how it compares, hopefully more of my anti-depressant will be out of my system making this a bit stronger.

Edit: Next day and I still have minor trails on moving objects haha, HPPD is fun

Does anyone have the receptor binding profile for 25C-nBome? Is it basically assumed to be the same as 25I, with maximal activity being at 5HT2A, followed by 5HT2C, 5HT6 and then 5HT2B?

The activity of my anti-psychotic is mainly at the 5HT2A receptor, which does seem to be responsible for the majority of the effects of this drug. This explains my slightly lackluster trips. My anti-depressant hits basically all the serotonin receptors with inverse agonism/antagonism, which would further reduce it. Unfortunately my anti-psychotics half life is roughly 75 hours so it makes the idea of skipping a few doses to trip harder basically impossible, it would take weeks. My anti-depressant only has a half life of 30 hours on average, so reducing that to enhance a trip is no biggie.

For a first time user of psychedelics, who want a real tripping experience, does 750ug orally sound like a good dose?

 

[zn13bt]

I'm going to be trying this tomorrow. Would 600ug bucally be a good dose for a first-timer? I've taken 25I several times now at doses of 800ug to 1.3mg, and from what I understand, 25C is a bit more potent.

 

[IamMe90]

I'm pretty sensitive to 25i (1.6mg buccal was too much for me one time) and 1mg buccal of 25c was pretty light. Great, but definitely ++ material (maybe on the slightly higher end of it).

 

[SerAg]

Id be rather interested concerning information on the HCl Salts Molar Mass and experiences with bucal absorption compared to complexed freebase.

 

[Psymask]

I cannot wait to try this stuff. I had a go with a blotter but I don't believ it did it justice. Got somethin to put up my nose now. Woop. Will be reporting very soon. It all sounds so wonderful. I tried some at glade but ky concoction was large and its effects perhaps lost amongst all of the other psychedelics. Such a beautiful festival tho.

 

[zn13bt]

I'm pretty sensitive to 25i (1.6mg buccal was too much for me one time) and 1mg buccal of 25c was pretty light. Great, but definitely ++ material (maybe on the slightly higher end of it).

1mg turns out to be WAAAAAY farther than I wanted to go today. Oooooops. :D

 

[zn13bt]

IamMe, you and me must have really different ideas about what constitutes a +2. Or I'm just really, really sensitive to this material.

I made the same mistake with DOI vs. DOC; I tried DOI once and it was interesting but manageable the whole time, so I figured DOC would be no problem, but that one turned out to be a full-on ZOMG WHY ARE THE SPACE ALIENS SPEEKING TO ME IN MY BRAAAINZZ experience. Likewise, I've had a bunch of 25I trips that were amazing and magical, but still I felt relatively in control the whole time. Today on 25C though, for a few hours it was just total sensory onslaught of confusion and babbling madness oozing out of every pore of everywhere all at once and there was no way I could stop it. At one point I closed my eyes and immediately I saw innumerable faces looking at me from everywhere, and it was like the entire universe was looking at me, including me looking at myself, which had shrunk to just a point of nothingness from which everything was being perceived. And it felt like there were the seeds to entire other universes laying hidden inside of me, and I was overwhelmed with gratitude.

So yeah, I would say this is just a bit more than "++ material (maybe on the slightly higher end of it).". :D I'm totally blown away, but in a good way. It's five and half hours now after dosing 1mg, and I'd say *now* I'm at a high +2. Next time I try this I'll definitely stick to my original plan of only doing 600ug.

 

[IamMe90]

Haha yeah my 1mg experience with this was nowhere near the intensity you described. Sorry for the dosage recommendation didn't work out! But YMMV and all

 

[zn13bt]

Nah it's ok, this isn't the first time I've followed other BL'ers dosing recommendations and gotten in waaay over my head. I guess I'm just more sensitive to psychs in general than most of the posters here. You'd think I'd learn my lesson by now...oh well. :D

 

[Redbong]

I found 600ug underwhelming and 900ug (the highest I've taken it) almost overwhelming. The dose response curve on 25c seems mighty steep to me. I've found 800ug to be just about perfect. All doses were administered buccally. I think I'll shoot for 800ug tonight.

 

[sn23]

I'm totally blown away, but in a good way.

Hehe, sounds like quite the unexpected experience. Glad you came out of it in one piece

I guess we should carefully add more information about preparation and ROA when reporting a tried dosage.

I found water soaked (15-30 mins.) and mushed (to fibers) blotters IR to lead to very nice and comfortable ++/borderline +++ at 800 µg and 1200 µg. Application was over the course of an hour in 400 µg portions.
Then I changed to a solution of the hydrochloride in 20% EtOH/water. 360 µg equivalent of this liquid intranasally was quite different to previous tests: very steep ascend to a full-on +++ in 25 mins. and then it climbed some more over the next 30-60 mins. Expecting something similar to the previous plugged experiences I was unprepared for such a wild and strong come-up but besides that no side effects were noted.

I'd say that the ROAs' kinetics have a big influence on the character of the trip, so factor this in when following dosage advises.

 

[Transform]

I'd agree with that completely. I think there is inevitable swallowing with sublingual, whereas nasal is very efficient and sudden, which makes it actually stronger and makes it feel stronger too.

 

[Tabtastic]

Hey guys, looks like this threads been dead for a minute but I have a question and I'm in urgent need of an answer asap.

So I bought a few grams of freebase a little while ago and it arrived today safe and sound. However, I couldn't get to it at the time it came and had to have a friend pick it up. Problem is I just realized IT'S REALLY FREAKIN HOT where I live and it's likely been in his car all day cooking at 100+ degrees (and it's probably even more since it's in the car, the windshields magnify the heat and all that).

Please someone if you can give it to me straight - is my precious powder going to be all right? Or am I out for the hundreds of dollars I paid for it?

~Tab

 

[TheAzo]

Hey guys, looks like this threads been dead for a minute but I have a question and I'm in urgent need of an answer asap.

So I bought a few grams of freebase a little while ago and it arrived today safe and sound. However, I couldn't get to it at the time it came and had to have a friend pick it up. Problem is I just realized IT'S REALLY FREAKIN HOT where I live and it's likely been in his car all day cooking at 100+ degrees (and it's probably even more since it's in the car, the windshields magnify the heat and all that).

Please someone if you can give it to me straight - is my precious powder going to be all right? Or am I out for the hundreds of dollars I paid for it?

~Tab

You're probably fine; all indications sofar are that the NBOMe series is of comparable stability to the other phenethylamines.

However, i'd take a look at it first - Is it yellow or something awful like that? If so, that's a bad sign.

In any event, prepare a sample of the appropriate dosage of it, and take it - does it provide the level of effects that you would expect from that dose? I have to assume that if you bought several grams of it, you're quite familiar with the, and should be qualified to make this judgement.

 

[Anon0631]

Rectal administration of 500µg 25c-NBOMe gave disappointing results. I would not recommend this as an ROA.