Jakeperson
Bluelighter
Thats the thing even at fairly high doses LSD produces not much more than threshold and side effects. Shrooms only give nausea, 2c's haven't been a problem.
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The Big and Dandy NBOMe-2C-C (25C-NBOMe) Thread
- Thread starter Lawrence
- Start date
sekio
Bluelight Crew
This drug lacks the "broad-spectrum" activity of most of the 2C drugs and would therefore not be expected to be very effective if LSD doesn't produce effects.
skillet
Bluelighter
- Joined
- Sep 13, 2010
- Messages
- 1,138
Says who? If that's by analogy to 25I-NBOMe, Ettrup et al. reported that affinities at 5-HT2, 5-HT6, 5-HT1A and D3 were within two orders of magnitude of that at 2A. So they're probably not that selective. And if anything is broad-spectrum it's LSD.
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pharmakos
Bluelighter
LSD and 25C-NBOMe might both give "narrow spectrum" effects, but there's no reason that i can see to believe that they focus on the same part of the spectrum!
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tregar
Bluelighter
Someone had asked a question at the beginning of this thread about how this stuff is measured out...
I'm pretty sure how researchers are weighing this out is by weighing out 100mg on a .01 or .001 scale (a .001g accurate scale is a highly recommended), adding the 100mg to 100ml of water, in volumetric solution this will reach equilibrium so that 1ml of it can be sucked up into a 1ml insulin syringe, so that you then have 1000ug in 1ml, each 1/10th of ml then equal to 100ug of material. if using a .01 scale, the 100ug measured out material would vary from inbetween 90ug to 110ug. if using a .001 scale, this variance would be much less.
I also recall reading in the past bodybuilding forums that people were having success by simply placing a layer of beta-cylodextrin powder (still available from auction sites) over the hydrophobic testosterone powder, giving it a short while to "complex", no spinning of powders necessary, it was said to be just as effective as stirred solutions...so I would imagine if you shot out 300ug or so of water-dissolved material onto a blotter which has allready had the 7-sugar cyclodextrin molecule powder applied/dissolved into it, that you should then apply a small layer of cyclodextrin to the top of the blotter allowing it to absorb into the blotter as well, this should hopefully then be sufficient for creating a complexed material, ready for buccal absorption in between top gum and cheek.
I'm pretty sure how researchers are weighing this out is by weighing out 100mg on a .01 or .001 scale (a .001g accurate scale is a highly recommended), adding the 100mg to 100ml of water, in volumetric solution this will reach equilibrium so that 1ml of it can be sucked up into a 1ml insulin syringe, so that you then have 1000ug in 1ml, each 1/10th of ml then equal to 100ug of material. if using a .01 scale, the 100ug measured out material would vary from inbetween 90ug to 110ug. if using a .001 scale, this variance would be much less.
I also recall reading in the past bodybuilding forums that people were having success by simply placing a layer of beta-cylodextrin powder (still available from auction sites) over the hydrophobic testosterone powder, giving it a short while to "complex", no spinning of powders necessary, it was said to be just as effective as stirred solutions...so I would imagine if you shot out 300ug or so of water-dissolved material onto a blotter which has allready had the 7-sugar cyclodextrin molecule powder applied/dissolved into it, that you should then apply a small layer of cyclodextrin to the top of the blotter allowing it to absorb into the blotter as well, this should hopefully then be sufficient for creating a complexed material, ready for buccal absorption in between top gum and cheek.
Jakeperson
Bluelighter
Well then looks like the only way to really know is to find out. I will give this a whirl tomorrow night.
Mung Hunter
Bluelighter
I have a question regarding dilution. I have diluted 10mg of 25c-nbome, and 10mg of 25d-nbome separately into 20mg of water each. Meaning they are diluted at a ratio of 500ug/ml. I used regular bottled water and shook them around a bit and they seemed to dissolve just fine as I could not see any particles separate from the water. I also know that this was a good quality chemical as the vendor I bought it from has an amazing reputation and everything else I've received from them has been great.
For some reason doses up to 750ug had no effect on people. I made sure I got all 11mg(they gave 1mg extra just so you got at least 10mg) out of the bag because I dropped water into the bags, and then extracted it with a pipette. Any idea why these would have had no effect on people? I kept them inside amber vials away from sunlight and heat. I also only diluted them about 3 days before they were used so they shouldn't have been in the solution long enough to degrade. Also the doses were taken sublingual, and held there for a minimum of 5 minutes. The only thing I can think of is, I don't believe I shook the solution just before ingestion, but as I said there are no visible particles in the solution so would I need to shake it again? Do you think the remaining part of the solution has become much more potent now because it was not shaken before ingestion?
For some reason doses up to 750ug had no effect on people. I made sure I got all 11mg(they gave 1mg extra just so you got at least 10mg) out of the bag because I dropped water into the bags, and then extracted it with a pipette. Any idea why these would have had no effect on people? I kept them inside amber vials away from sunlight and heat. I also only diluted them about 3 days before they were used so they shouldn't have been in the solution long enough to degrade. Also the doses were taken sublingual, and held there for a minimum of 5 minutes. The only thing I can think of is, I don't believe I shook the solution just before ingestion, but as I said there are no visible particles in the solution so would I need to shake it again? Do you think the remaining part of the solution has become much more potent now because it was not shaken before ingestion?
Jakeperson
Bluelighter
It's possible but there does seem to be a lot of variance on effects from sub-lingual dosing
Jakeperson
Bluelighter
Did they taste bitter?
teh1buck
Bluelighter
Any reports of flipping this with MDMA?
Rorthron
Bluelighter
This may be way off but was it the freebase or the HCl salt? the former is basically insoluble. In my case i had the freebase. When i first added water to it it just clumped together in the bottom of the vial. So basically very few 25-C in solution. I calculated the solution molarity and added the equivalent of HCl to make the salt. The clump dissolved and it was pretty effective at 200 ug dosages.
skillet
Bluelighter
- Joined
- Sep 13, 2010
- Messages
- 1,138
It sounds like the salt if it dissolved easily. I think it's just that sublingual dosing is really hit and miss. Maybe people should experiment with surfactants, or cyclodextrin like tregar said, if they insist on going this route, it might make it more reliable. I guess simply wetting a blotter with a tiny amount of shampoo or washing up liquid (unless, of course, you can get pure surfactants) to a blotter before injesting could help a lot, but be sure to lower the dose to 1-200ug max, at least at first, if anyone is going to try that.
People have reported a large increase in potency by combining with a surfactant, but I can't remember if it was with sublingual administration or insufflation, or both.
People have reported a large increase in potency by combining with a surfactant, but I can't remember if it was with sublingual administration or insufflation, or both.
Survived Abortion
Bluelighter
I took ~375ug rectally at 20:00, as close to that dose as I could get as there there was still a bit of liquid left in the nozzle after administration. The way it comes on is intense, I didn't expect the body-rush. I felt first alerts almost immediately, within about a minute after administration, and I was coming up fast within 5 minutes. The body-load is overwhelming, 
I'm astonished people are able to handle the much higher doses people are reporting here. Before there were any visuals, I felt an incredible push inside my chest, like my heart was being squeezed, my face felt tight and I had an immense amount of pressure inside of my physical body. My pores opened almost immediately, there is an quick onset of perspiration with this drug. My heart rate was noticeably elevated, and my blood-pressure 'felt' high. A strange headache which set in with the increased pressure lasted around 10 minutes. Temperature elevation was noted a couple of hours in.
Visually, the body-peak happened before the visual one, but even so there was not really much in the way of visuals. The initial rush provided an onset of colour saturation and strobing, but even these effect were far milder than I had expected by what is reported. Audials increased with the visuals, with a slight rise in tinnitus or universal noise, but again quite mild. The 'visuals' (or the visual aspect) peaked at about an hour to an hour and a half and consisted of simply an enhancement of the aforementioned colour saturations along with a slight expansion of the visual depth and size and very very mild cartooning, almost non-existent. There was no appreciable music enhancement effects. If I hadn't known I had taken a drug, I would have thought that it just was another flux of HPPD.
I must say that I'm a bit disappointed. I hadn't expected the negative body-load to be so high in comparison to the psychedelic effects, especially at such a small dose. Maybe it had to do with the route of administration, but I hardly think that insufflation would make those things better. Sublingual may be easier. Or it could be that I'm becoming more sensitive to psychedelics these days as I use them far less often than I used to. I have also been in a fairly anxious mindset for many months now, so that could have contributed.
I'm tempted to see what lie further down the rabbit-hole with this one, as other people are clearly enjoying it. But I cannot reconcile those body effects. It may be that I need to become a lot more physically healthy before I embark on such potent and unknown chamicals as the NBOMEs. Tryptamines have always been good to me (mostly) as have the 2C series.
I'm astonished people are able to handle the much higher doses people are reporting here. Before there were any visuals, I felt an incredible push inside my chest, like my heart was being squeezed, my face felt tight and I had an immense amount of pressure inside of my physical body. My pores opened almost immediately, there is an quick onset of perspiration with this drug. My heart rate was noticeably elevated, and my blood-pressure 'felt' high. A strange headache which set in with the increased pressure lasted around 10 minutes. Temperature elevation was noted a couple of hours in.Visually, the body-peak happened before the visual one, but even so there was not really much in the way of visuals. The initial rush provided an onset of colour saturation and strobing, but even these effect were far milder than I had expected by what is reported. Audials increased with the visuals, with a slight rise in tinnitus or universal noise, but again quite mild. The 'visuals' (or the visual aspect) peaked at about an hour to an hour and a half and consisted of simply an enhancement of the aforementioned colour saturations along with a slight expansion of the visual depth and size and very very mild cartooning, almost non-existent. There was no appreciable music enhancement effects. If I hadn't known I had taken a drug, I would have thought that it just was another flux of HPPD.
I must say that I'm a bit disappointed. I hadn't expected the negative body-load to be so high in comparison to the psychedelic effects, especially at such a small dose. Maybe it had to do with the route of administration, but I hardly think that insufflation would make those things better. Sublingual may be easier. Or it could be that I'm becoming more sensitive to psychedelics these days as I use them far less often than I used to. I have also been in a fairly anxious mindset for many months now, so that could have contributed.
I'm tempted to see what lie further down the rabbit-hole with this one, as other people are clearly enjoying it. But I cannot reconcile those body effects. It may be that I need to become a lot more physically healthy before I embark on such potent and unknown chamicals as the NBOMEs. Tryptamines have always been good to me (mostly) as have the 2C series.
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bob_arctor
Bluelighter
just for clarification, you mean 375 mcg right? 375 mg would be an insanely high dosing.
Survived Abortion
Bluelighter
^Oh yes, oops. Thank you for pointing that out! Corrected to ~ug.
Jakeperson
Bluelighter
1mg plugged made for one of the best and most colourful experiences I have ever had.
Think 2c-c and acid combo with a bit of 2c-t-7 body feeling. IME anyways.
Any one had much experiences with higher doses?
Think 2c-c and acid combo with a bit of 2c-t-7 body feeling. IME anyways.
Any one had much experiences with higher doses?
Jakeperson
Bluelighter
This stuff does work on Mirtazapine. Which I am off now anyways.
Just took a moderate dose of lsd. I might snort some 25c-nbome depending on how strong this tab is feeling in 30-45 mins.
Any one got any idea of how long before tolerance will kick in? I'm guessing it would be the same as with dosing more LSD, around an hour into it.
Just took a moderate dose of lsd. I might snort some 25c-nbome depending on how strong this tab is feeling in 30-45 mins.
Any one got any idea of how long before tolerance will kick in? I'm guessing it would be the same as with dosing more LSD, around an hour into it.
yoyo50
Bluelighter
Got some blotters 350ug, coming at end of the week hopefully, seeing as sub lingual is rubbish at best, what would be the best way, adding x amount of water to a tab in a bottle cap then sniff the water?
Cheers
Cheers