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The Big and Dandy 4-AcO-DMT thread - New incarnation

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I need some input about tolerance with this chemical. Would 4 days be enough to wait? I'm talking purely from a pharmacological viewpoint, and not psychologically.

Has anyone examined 4-aco-dmt tolerance?
A while ago I did the following:

Day 1: 8mg
Day 2: nothing
Day 3: nothing
Day 4: 15mg
Day 5: 5mg

Contrary to my expectation, there seemed to be no tolerance even at the end. But a caveat: these are extremely low doses for me. I regularly take 50mg, and even that only brings me to a nice +2. I find this a useful chemical for stimulating creativity and boosting mood, but it lacks any depth or edge for me. So perhaps if I'd been taking more typical (for me) doses I would have noticed tolerance.
 
I was wondering if anyone here has experience with the sublingual administration of the 4 aces. Onset, duration, etc?
Yes, in fact this is the only way I do it now. It doesn't seem to differ much from oral, but I haven't done a real side by side comparison. For me it's very quick both ways: up in 45 minutes, back to near baseline by 2.5 hours, but the afterglow (which I enjoy more than the peak) can last another 3+ hours depending on dose.
 
A while ago I did the following:

Day 1: 8mg
Day 2: nothing
Day 3: nothing
Day 4: 15mg
Day 5: 5mg

Contrary to my expectation, there seemed to be no tolerance even at the end. But a caveat: these are extremely low doses for me. I regularly take 50mg, and even that only brings me to a nice +2. I find this a useful chemical for stimulating creativity and boosting mood, but it lacks any depth or edge for me. So perhaps if I'd been taking more typical (for me) doses I would have noticed tolerance.

50mg?!! +2 experience? Do you analize your psilacetin?? (in energycontrol for example) 8mg (+1 for sure) was perfectly active on me, 50 its a pretty overdose, that psilacetin can´t be real psilacetin or the concentration of alkaloid is very low.
 
50mg?!! +2 experience? Do you analize your psilacetin?? (in energycontrol for example) 8mg (+1 for sure) was perfectly active on me, 50 its a pretty overdose, that psilacetin can´t be real psilacetin or the concentration of alkaloid is very low.
This is multiple batches from reliable vendors. 20mg is a strong +3 for almost everyone. 44mg put someone in the ER with a psychotic break from which he hasn't begun to recover two years later (other people here have written about that person).

I've written about this elsewhere in detail, but the short answer is I believe my frustratingly high tolerance (to every psychedelic I've tried, synthetic and organic) is a residual effect from SSRIs that I discontinued two years ago.
 
oh! ok, sorry for precipitate prematurely a judgement about you, I didn´t know this very high tolerances in psychedellics.
 
<in regards to dextermeths trip report on previous page>

i've had alot of trials with 4-aco-dmt that felt alot like a good mdma trip. In fact, the first time i let my wife try it out, she even remarked herself half way thru the trip - "are you sure you didn't give me mdma?"

i've also been on 4-aco-dmt and thought to myself how much it felt like 2c-b on at least 2 or 3 occasions... Not exactly the same, but pretty darn close...
 
I'm up and down in 4 hours total too. Wonder what the difference in duration is due to?
Oddly it's not dose dependent. I'm struck how the both time course and the general character of the experience seem consistent from 5 mg up to 50 mg. The big difference is the the length and intensity of the euphoric afterglow. In fact, I sometimes think of the whole 2.5 hour trip as just the come up to the more subtle but longer lasting (and in my experience useful) afterglow state.
 
first contact with 4-aco-dmt

I wrote this experience on other thread, but this thread is more suitable and I decided to put it here:

Dosage: 8 mg
Onset: 17.30
Come up: +45-50 min
Peak: +2 hours
To baseline: +4-5 hours

YES! Is the first psychedellic experience without any anxiety! very very smooth ride! (at this level). The come up passes very gradually with some nervousness and a bit cold feeling in hands, but really in a smooth ride without panic, without paranoia, without anxiety! I don´t notice any mindfuck, the mindset is very clear headed, my head was empty of thoughs! very comfortable at all.

Physically is brutally WARM, fire under my skin in hot waves! touch me feels awesome and all experience is very very sedative, it´s a contemplative drug, very static experience just relaxing at all times, nice contact experience ^^ .

Very nice but a bit "light" experience. I hope that in 12-15 mg level the experience continue being comfortable at all :)
 
Forgive me if the answer is somewhere in this thread already but I haven't time to read through it right now. I just wanted to know how stable the substance was. Let's say just as the fumarate salt, not dissolved or anything. How long do you think it would last in a sealed, air tight sample vial wrapped in aluminum foil and placed in a dark closet?
 
Seems pretty stable...I made a few capsules of it that I never ended up using...they have been at room temperature for almost a year and have not discolored.
 
I kept some 4-AcO-DMT fumarate in my wallet all summer and it didn't degrade at all.
 
Yeah, I've had my sample for well over a year, and at least 6 months of that were at room temperature, and it looks and works exactly the same. I've had pure 4-HO-DMT a fair number of times as well and I can assure you that if any of the AcO "degraded" into psilocin, it was not enough to be able to change the effects.
 
<in regards to dextermeths trip report on previous page>

i've had alot of trials with 4-aco-dmt that felt alot like a good mdma trip. In fact, the first time i let my wife try it out, she even remarked herself half way thru the trip - "are you sure you didn't give me mdma?"

i've also been on 4-aco-dmt and thought to myself how much it felt like 2c-b on at least 2 or 3 occasions... Not exactly the same, but pretty darn close...

I've only done "4aces" twice now, but I'd say if I was to compaire it at ALL to MDMA, it's only because the shit is so fucking perfect that one feels pure "XTC"! :)
 
I am sure this has been asked and answered a hundred times already but if someone were to want to seperate their powder into doses, would would be the recommended amount. 25mg seems to be too intense for some, but perfect for others. 12.5mg maybe?
 
12,5? wow! my pocket scale only have a 0.002 readibility (tanita), what scale you have? (sorry for bad english and off-topic...). 10-12 mg its a very nice start dose, controllable but effects very present and fun.
 
12.5mg is a good starting point... you'll definitely get full-on effects (unless you have tolerance), but it won't be too strong. 25mg is great for me, but it will be very strong. The good thing about 4-AcO-DMT is that it's very smooth and really hardly produces any anxiety for most people, unlike psilocin and mushrooms (especially mushrooms). So it's pretty forgiving if you go too high. But 12.5 is still a good place to start. Actually, if I were going to divide out all of my powder beforehand into doses, I would probably do 10mg doses. Then you could take it in increments of 10, or evewn split one in half to go in between. Plus 10 is easier to measure exactly than 12.5.
 
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