Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

[Captain.Heroin]

So if something interacts with the mu opioid receptor then it interacts with ALL opioid receptors?

No. Buprenorphine just happens to interact with all of them (not every single last receptor, but mu, delta, kappa, and other receptors).

Most opiates only interact on the mu-opioid receptor, and have negligible if not inexistent affinities for the other opioid receptors. There are obvious exceptions, like methadone (also works as an NMDA antagonist), and nalbuphine, and tramadol.

 

[caseface99]

No. Buprenorphine just happens to interact with all of them (not every single last receptor, but mu, delta, kappa, and other receptors).

Most opiates only interact on the mu-opioid receptor, and have negligible if not inexistent affinities for the other opioid receptors. There are obvious exceptions, like methadone (also works as an NMDA antagonist), and nalbuphine, and tramadol.

Ok thanks that's what i was looking for. I suppose when i was saying "so buprenorphine works on the mu and kappa opioid receptors..." i shoild have said that it works only on those receptors because that's what i meant. I saw two different sources that only mentioned it being a mu partial agonist and kappa antagonist. Which lead me to believe that it only interacted with those receptors, which in turn lead to much confusion.

Thanks for clearing that up though, sorry if i wasn't being clear at first.

 

[stuckinaloop]

Tapering that long is stupid. Why not just get it over with in a few days?

So nieve. Why even waste time posting when you don't know shit.

Heroin withdrawal in a few days? maybe if you've been doing a bag a day for a week lol.

 

[caseface99]

So nieve. Why even waste time posting when you don't know shit.

Heroin withdrawal in a few days? maybe if you've been doing a bag a day for a week lol.

He was referring to my suboxone taper since i have been tapering for over 8 months, and he posted that after i said im going to stop tapering lower and jump off now a little bit before i was planning on it. He definitely wasn't talking about heroin and i don't think he was talking about jumping off of suboxone at like 12mgs.

I could be mistaken but i figured he was talking about me back when he posted that.

 

[Captain.Heroin]

Thanks for clearing that up though, sorry if i wasn't being clear at first.

No problem!

 

[catcalls]

Man, delta, mu, we are the agents of mu!?

Haha. That brings back some memories of drum and bass tunes.

You sure do learn a lot of science here in this thread.

I always found the more I took, the closer I got to OD! Haha.

 

[caseface99]

Man, delta, mu, we are the agents of mu!?

Haha. That brings back some memories of drum and bass tunes.

You sure do learn a lot of science here in this thread.

I always found the more I took, the closer I got to OD! Haha.

A lot indeed, I love Bluelight. I have always looked things up i was interested in learning before, but sometimes it can be confusing and requires clarification (as shown in the above few posts), and sometimes you just learn things by reading threads that you hadn't thought of looking up in the first place. At my rehab's after care group that i go to once a week the therapist loves me and is always urging me to go into a career somewhere in the field of addiction. It never seizes to amaze me how few people know remotely anything about drugs. I've seen posted before that the average Bluelighter is far more intelligent than the average druggie, and it's so true.

Also, Buprenorphine is actually difficult to overdose on by itself - in anybody with any sort of tolerance anyway. An overdose would generally be caused by mixing it with something like alcohol or benzos.

 

[Captain.Heroin]

It never seizes to amaze me how few people know remotely anything about drugs. I've seen posted before that the average Bluelighter is far more intelligent than the average druggie, and it's so true.

You mean "ceases", "seizes" is what the gov't does when they confiscate drugs, or it's what someone does when they are coming off of a heavy benzo/barb habit without having tapered.

What never ceases to amaze me is how much more I will know about pharmacology and medicine in general than pharmacists and doctors. The doctors and pharmacists in my area are so slow. One pharmacist said that you don't use insulin syringes to administer shots of Vitamin B12. 8) How do you administer it then, magic?

 

[HdoubleODeezy]

^ lol @ administration of b12 by magic.

 

[caseface99]

You mean "ceases", "seizes" is what the gov't does when they confiscate drugs, or it's what someone does when they are coming off of a heavy benzo/barb habit without having tapered.

What never ceases to amaze me is how much more I will know about pharmacology and medicine in general than pharmacists and doctors. The doctors and pharmacists in my area are so slow. One pharmacist said that you don't use insulin syringes to administer shots of Vitamin B12. 8) How do you administer it then, magic?

I knew the way i spelled it didn't look right haha. Thanks.

And i agree. The absolute worst is when doctors/pharmacists say that suboxone can't be abused/IVed. It cracks me up so hard.

That's great about the syringes. What, do they think an insulin syringe can ONLY be used with insulin? haha. 8)

 

[jamesBrown]

off topic but I like your avatar caseface99

....reminds me of peace, love, and happiness....which are things I like.

 

[HdoubleODeezy]

^ weird that you would say something about her avatar, as i just did in another thread lol.. i was wondering if she changed it recently because she's been a member a long time and i never noticed her until that big smiley face lol.

Anyway.. back on topic.. Kinda..

Whats for breakfast everyone? im starving.
maybe a dose of bupe, vistaril, tizanadine along with a kpin or 2 afterwards with some DMAA.

Yeah sounds good 2 me.. ill be back later. hopefully feeling nice

 

[jamesBrown]

^ weird that you would say something about her avatar, as i just did in another thread lol.. i was wondering if she changed it recently because she's been a member a long time and i never noticed her until that big smiley face lol.

Anyway.. back on topic.. Kinda..

Whats for breakfast everyone? im starving.
maybe a dose of bupe, vistaril, tizanadine along with a kpin or 2 afterwards with some DMAA.

Yeah sounds good 2 me.. ill be back later. hopefully feeling nice

8mg dilaudid and 2 100mcg fentanyl patches for breakfast

mmm...mmm good.

 

[HdoubleODeezy]

^ breakfast of crippled champions.

 

[catcalls]

Just did a google for Dilaudid. Remember a username with that drug in the title. Did not know it was an analgesic.

That said, I also googled Oxycotin, because that is another analgesic like Subutex even though completely different chemically.

I'm interested in these drugs, because you rarely hear about people abusing Oxy's even though they're supposedly available in the UK?

I also hear from an Internet friend in Florida, that OC has turned into OP. Which she said is real bad for her. I dunno why tho, something to do with time release?

Well, I've just taken my Subutex. I felt a little WD this morning. I think that was from the heavy Kratom session the night before this morning. I woke up at 12am (midnight) as well. I've been up ever since. That might be a reason for feeling the WD symptoms. Chills as always. I hate feeling cold!

I mean, we've got the heating on 16 Degrees C, and that should be HOT! But, this morning, I was shaking with the cold. Haha. I have not felt that way in months. Hope its not something to expect tomorrow, mainly because I'm taking the Kratom off for today. Only having my maintence dose and that will do me. Not trying to get a nod off of it.

 

[SkagKush]

james baby!

^ ya man breakfast of champions for sure, i wish at the moment i was doing the same.....haha, fucking work......

sleep then breakfast........

1mg soon tho.......

 

[caseface99]

^ weird that you would say something about her avatar, as i just did in another thread lol.. i was wondering if she changed it recently because she's been a member a long time and i never noticed her until that big smiley face lol.

Anyway.. back on topic.. Kinda..

Whats for breakfast everyone? im starving.
maybe a dose of bupe, vistaril, tizanadine along with a kpin or 2 afterwards with some DMAA.

Yeah sounds good 2 me.. ill be back later. hopefully feeling nice

Im totally a guy not a chick.


Haha. What made you think i was a chick anyway? That's funny.


On topic though, i dosed around .9 today rather than .5 just to see what would happen. I got a *slight* buzz, if anything it may have just been the lack of withdrawal producing mental euphoria which my brain relayed into physiological euphoria. Wasn't very strong, but definitely worth it. I don't say fuck it and give my body a break from the w/d's often so when i do it's awesome high or not.

Goin' to sleep now, looking forward to your response though doubleoheezy haha idk how i came off as a chick, legitimately interested in knowing.

 

[HdoubleODeezy]

Im totally a guy not a chick.


Haha. What made you think i was a chick anyway? That's funny.


On topic though, i dosed around .9 today rather than .5 just to see what would happen. I got a *slight* buzz, if anything it may have just been the lack of withdrawal producing mental euphoria which my brain relayed into physiological euphoria. Wasn't very strong, but definitely worth it. I don't say fuck it and give my body a break from the w/d's often so when i do it's awesome high or not.

Goin' to sleep now, looking forward to your response though doubleoheezy haha idk how i came off as a chick, legitimately interested in knowing.

i thought the "case" in your username was for "casey" the name. Which i know a girl with that name..
sorry, i won't make assumptions about people's sex over the internet anymore, it's kinda difficult. lol. sorry again. ..
it was nothing you said or did that made me think that, it was just the "case" popped up in my brain as short for casey, that's all, nothing personal.

 

[caseface99]

ha don't worry about it. "Case" is my last name, and growing up one of my friends older brother and his friends started calling me "Caseface" - the nickname stuck for years with that original circle of friends i had. I wish i hadn't put the "99" on though. I'd change it if i could but oh well.

Apologies for contributing to the derailment of this thread.


I've got 5 ounces of bali kratom in the mail and a sample of some other strain. I've got to make it last as long as possible once i jump because i know i won't be able to buy more.

Other than kratom I've got soup, juice, gabapentin, clonidine, cheese/sandwich stuffs, tangerines, bowflex, vitamins, Hemp seed oil (even better than fish oil), im sure a bunch more stuff that could help just can't think of it. I'm legitimately excited for this.

When i stop taking the kratom, do i need to taper it? I won't become dependent and extend/prolong/re-withdraw from the kratom after 3 or so weeks of dosing every day will i?

 

[HdoubleODeezy]

ha don't worry about it. "Case" is my last name, and growing up one of my friends older brother and his friends started calling me "Caseface" - the nickname stuck for years with that original circle of friends i had. I wish i hadn't put the "99" on though. I'd change it if i could but oh well.

oh iight..
i don't know the next thing to say to a guy after you just called them a girl then found out their in fact not a girl lol.. *awkward* ha.