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Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

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docs can be very skimpy, but this is also for your own good.....

bupe on days where thats all your taking must not be killing your pain very well, no? 1mg would b better than 8mg tho....
 
SkagKush said:
docs can be very skimpy, but this is also for your own good.....

bupe on days where thats all your taking must not be killing your pain very well, no? 1mg would b better than 8mg tho....
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I agree. allthough everyone is different. But different ideas are sometimes worth giving a try....they might even make a major positive impact on your life.
 
jamesBrown said:
I agree. allthough everyone is different. But different ideas are sometimes worth giving a try....they might even make a major positive impact on your life.
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Let's see:
  • can't play with my kids
  • can't do my own yardwork
  • can't wash my own vehicle
  • can't drive more than 10 miles
  • can't do house chores
  • can't even have sex


Yeah, I see lots of positives. Those are just the ones I can think of.

Ask questions before evaluation a situation.

Every since my doctor lowered my opiate intake my life has gone into the shitter. I've had to drop out of school and I can't find a job.

I'm switching doctors on Wednesday. The guy is known to be generous in the right situation.
 
If your quality of life is that bad it is time to try every pain doctor in the entire city, there has to be one that will understand your situation. Those side effects sound far worse than the effects of having a long term opiate addiction so I think it would be more than warranted to up your dose. The advantage of suboxone over other opiates is the long action and it has a weaker mental effect due to only being active on one receptor so you won't be fucked up all day long and will still be able to do things.

May I ask what happened?
 
pixplzthx said:
Let's see:
  • can't play with my kids
  • can't do my own yardwork
  • can't wash my own vehicle
  • can't drive more than 10 miles
  • can't do house chores
  • can't even have sex


Yeah, I see lots of positives. Those are just the ones I can think of.

Ask questions before evaluation a situation.

Every since my doctor lowered my opiate intake my life has gone into the shitter. I've had to drop out of school and I can't find a job.

I'm switching doctors on Wednesday. The guy is known to be generous in the right situation.
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Im not sure what you were trying to say there. Where you saying that I said something wrong or seomthing? Im sry, I have a hard time understanding sarcasm over the internet if that was indeed sarcasm, if it wasnt, than im still not sure what your trying to say....but either way, I hope you figure out your problems.
 
rolls_ said:
If your quality of life is that bad it is time to try every pain doctor in the entire city, there has to be one that will understand your situation. Those side effects sound far worse than the effects of having a long term opiate addiction so I think it would be more than warranted to up your dose. The advantage of suboxone over other opiates is the long action and it has a weaker mental effect due to only being active on one receptor so you won't be fucked up all day long and will still be able to do things.

May I ask what happened?
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My chronic neck pain is congenital (Spinal stenosis). My lower back has two broken disks between S1 & S2, S & S3. This causes a ton of sciatica pain which has actually made me fall down.

I have no idea why my current doctor changed my pain dosing regimen. Just three months ago he had me at a very nice dosage that kept the pain manageable and kept me productive and active.

Suboxone is about as effective as codeine (or less) when treating my pain.
 
Yeah on 1mg I'm not surprised, I've heard of chronic pain patients being put on 16mg+ for life before, 1mg wouldn't even last the entire 24 hours.
 
actually patients who are prescribed suboxone for pain arent given dosages that high because bupe loses its pain killing properties at high doses. A 1 mg dose is more like it. MAybe 2 mg's but thats about as high as it gets when it comes to painkilling as far as I know. 16 mg's is strictly an opiate maintanence dose.

but if you have serious pain especially when dealing with spinal issues, i would think you should be prescribed something stronger than suboxone. I would think a full agonist would fit the bill much better. I wonder why your doc changed your meds randomly pix
 
Higher doses of bupe allow much more of its antagonistic properties to "come up" or show themselves and this results in many negative side effects.

Also....the painkilling properties of bupe come primarily from its full agonist metabolite norbupe which is only active in tiny doses.

This is also why people who are on suboxone, dont get any more effect if the take several times there normal dose. The most that will do is maybe make them tired and give them a headache.
This is why they chose such small doses for Temgesic(the painkiller formulation of bupe) when it came out. i think its only comes in pills that are either 0.2 or 0.4 mg's. If you take doses much higher than this, the norbupe doesnt bind to your opiate receptors, and the suboxone loses alot of its painkilling properties. I dont have the info on the exact "mechanism of action" of how these drugs work on your brain in this scenario on hand right now....but I know it has been discussed in detail in another thread a while back. You can do a search for it and find all the answers if you are interested in knowing that much detail. Also, i think CaptainHeroin knows some of that info off the top of his head so if you want, you could ask him personally and maybe you can get your answers that way.
 
Would it be possible to convert bupe to norbupe with some easy kitchen chemistry?

(Not asking how just if its possible)
 
pixplzthx said:
I'm just around 1 mg of Suboxone. Just like needles are addicted to the preparer, am I addicted to my ROA as well. However my ritual is rectally. I must say that there is a huge increase in good vibes (euphoria if you want t call it that). I can go all day on one dose but on occasion I will dose in the afternoon (if it is before 3 pm) if the effects are feeling very thin.

I must admit that I many use subs to get from opiate prescription to opiate prescription. I am a chronic pain patient (10 years and counting) that is under-dosed. When I am on my normal pain meds, I am not looking for total relief. That's a pipe dream. I'm simply looking to move my 7-8 pain to 4-5 pain. The best the doctor ever gets me to is around 6, at best.

His comment is always the same "Well, remember; You're never going to be pain free."

Yeah, not shit. But I'd at least like to play with my kids or mow my own lawn.
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That's a really pessimistic doctor, it is possible to be pain free. Maybe not all the way to a zero, but definitely 3-4 if your doctor cared enough to give you adequate pain relief.

I'm not familiar with what kind of pain you're suffering from but I think it's really shitty for a doctor to rub it in your face all the time "you'll never be pain free". :\

Smokey McPot said:
Would it be possible to convert bupe to norbupe with some easy kitchen chemistry?

(Not asking how just if its possible)
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It wouldn't do you much good. As far as I am aware, norbuprenorphine doesn't cross the BBB as buprenorphine does.

And if it's possible or not, I doubt it is, at least with "easy kitchen chemistry".
 
Captain.Heroin said:

It wouldn't do you much good. As far as I am aware, norbuprenorphine doesn't cross the BBB as buprenorphine does.

And if it's possible or not, I doubt it is, at least with "easy kitchen chemistry".
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How does norbupe have an effect when metabolized in vivo? I was under the impression that it is metabolized in the liver into norbupe so it would still have to cross the BBB to have an effect unless it is metabolized into norbupe within the brain itself which doesnt happen i dont think, or does it?
 
Smokey McPot said:
How does norbupe have an effect when metabolized in vivo? I was under the impression that it is metabolized in the liver into norbupe so it would still have to cross the BBB to have an effect unless it is metabolized into norbupe within the brain itself which doesnt happen i dont think, or does it?
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I might be wrong about that, then. I cannot remember where I read that.

As it stands I have no idea how to convert buprenorphine into norbuprenorphine, so if that would be ideal and actually yield better effects, I wouldn't know where to begin.
 
jamesBrown said:
actually patients who are prescribed suboxone for pain arent given dosages that high because bupe loses its pain killing properties at high doses. A 1 mg dose is more like it. MAybe 2 mg's but thats about as high as it gets when it comes to painkilling as far as I know. 16 mg's is strictly an opiate maintanence dose.

but if you have serious pain especially when dealing with spinal issues, i would think you should be prescribed something stronger than suboxone. I would think a full agonist would fit the bill much better. I wonder why your doc changed your meds randomly pix
Click to expand...


He does it (randomly) to force me to go to an expensive specialist that tells my primary the same thing he always tells him. Best of all the specialist is always booked out for 6 weeks.

So my meds get cut in half and my quality of life goes right to the couch.

I going to try to switch primaries this week.
 
pixplzthx said:
He does it (randomly) to force me to go to an expensive specialist that tells my primary the same thing he always tells him. Best of all the specialist is always booked out for 6 weeks.

So my meds get cut in half and my quality of life goes right to the couch.

I going to try to switch primaries this week.
Click to expand...

I hope you find a more compassionate doctor! No one deserves to live with debilitating pain. <3
 
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