Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

[NiteShadeX]

Been on Suboxone for a month... i'm REALLY scared about something....

I started Suboxone 1 month ago, i'm taking 8mg a day (4mg snorted twice a day). I was always the guy with the low tolerance, my oxy tolerance was 30mg, and its been like that since I started using oxy about 2 years ago.

Well here's my question, IM FUCKING NERVOUS.... Some time halfway through the month I wanted a nice fix of oxy, so I stopped taking the Subox for 3 days. On the 3rd day snorted my 30mg Roxi like usual, but I felt ABSOLUTELY NOTHING! So I snorted another 15mg, still nothing, then the other 15mg, STILL NOTHING! Thats 60mg of oxy, double my usual dose thats supposed to get me feeling really good... except I felt nothing at all....

Does the Suboxone make you immune to opiates? Or is it temporary? Or did I not wait long enough? Will it raise my oxy tolerance?

 

[BaybeX]

You are on wayyy too much Sub. I had a 300-450mg/day Oxy habit and 2-3mg of Suboxone held me.

8mg of Sub is a lot more than 30mg of Oxy. Your tolerance has skyrocketed. Sorry, dude.

 

[weltschmertz]

You will be allright since you are on Buprenorphine. Just dont abuse other stuffs.

I dont understand dosages for oxy and hydros cause we dont have them here in South Europe. If you know some names or generics please tell me.


I v been on tramadol 10 years,
-then 2yrs on H and
-then quit H and have 3 months on 400mg trams a day.
- 6months ago i went to SUB program and i am on 8mg a day,10mg Diazepam,2x300mgDepakote(for seizures) and whole lotta weed.

2mgBuprenorphine calm me down but i have not much energy.When i take 8millies i feel much more confortable.


1.Is this good for me,should i reduce buprenorphine dose?

2.And may you guys sugest me a ROA ,should i be dipp between my gum and my lips, snort it,or sublingual like it supose to?

3.Wich antidepressant should i choose. Maybe Asentra? Reccomend something!

4. Other tips from yours experience.

Thank you all. Have a happy day.

 

[sublime143]

dude not trying to scare you or anything but you have been taking totally too much sub and now imo the withdrawls will be way worse coming off of the sub than if you just came ct off your oxy habit. I dont know what your doctor was thinking putting you on that much. Also now your tolerance is so much higher that you will need alot more oxy to achieve the same effects as before.

 

[HighonLife]

yea dude, coming off 30mg of oxy woulda been much easier then coming off 8mg Bupe, sorry to tell u this

this is why some people should not seek out maintenace treatment too quickly without thinking of the pros n cons first

 

[187coopa]

CUT YOUR DAILY DOSE!!!!!11

Im in the same boat as you.

I take no more than .5mgs a day.

take ur dose all at once too.

Trust me take .5mgs snorted and ur gonna be really happy with the results.

 

[Captain.Heroin]

It is likely that buprenorphine has raised your tolerance.

Try tapering with Suboxone, before using full agonists again, or simply wait a solid while longer than you originally did.

-> Suboxone Mega Thread

 

[Deveel]

I tried to IV about .5mg of suboxone last night, couldnt find a vein didnt feel like spending too long in the bathroom at my halfway house searching for a vein so I broke the tip off the needle and plugged the dose, I sorta felt buzzed from it.

I can't help feeling like I've relapsed though because I took the medication in a way its not prescribed to be taken, to me thats a relapse. I got rid of my rigs this morning and I'm gonna stick to the sublingual route.

It just doesnt make sense to me, trying to get clean and get your life straightened out yet still practicing dope feind drug addict behavior like shooting or snorting suboxone. IMO thats not what being clean is about.

 

[Paulination]

I have started using generic subutex and its a so much cheaper I have also started to filter out the inscribed for nasal use I have to say I'm quite surprised I thought it would be a lot less euphoric but its about double if u didn't filter out the inactives

 

[Ricochet2049]

I thought snorting Suboxone wouldn't work? I've been reading about people snorting very low doses (and it would be easier than splitting up a 8mg pill into .5mg or lower), and getting the same effects or better.

I thought Suboxone wasn't able to be absorbed any other way than sublingually?

 

[SubDude]

I thought snorting Suboxone wouldn't work? I've been reading about people snorting very low doses (and it would be easier than splitting up a 8mg pill into .5mg or lower), and getting the same effects or better.

I thought Suboxone wasn't able to be absorbed any other way than sublingually?

Subs can be used effectively just about anyway other than swallowing whole. They are prescribed to be used sublingually but many BL'ers snort and IV for maximum bioavailabilty. IMO prescribled use is best for long term maintenance.

 

[Paulination]

U can use suboxone any way u like as but if u filter out the inactives with a needless syringe and compacted cotton its a lot better look under nasal administration of suboxone under the first page of this thread

 

[jamesBrown]

I thought snorting Suboxone wouldn't work? I've been reading about people snorting very low doses (and it would be easier than splitting up a 8mg pill into .5mg or lower), and getting the same effects or better.

I thought Suboxone wasn't able to be absorbed any other way than sublingually?

Suboxone can be taken sublingually, intranasally, intraveinous, rectally, and orally(but it would barely work orally, and prob make you feel sick).

the bioavailability's(BA) for the different routes are...

SL ~30%
SL+alcohol ~70%
Intranasal ~50%
IV ~100% (please use micron filter)
rectal ~54%
oral- ~10%
****************
you can also do it intramuscular but I dont reccomend it as it could very easily cause abscesses....IM ~68%

 

[DkBlaze1]

YO captain heroin I thought that this thread was exempt for the no Price rule ???

 

[DkBlaze1]

I live in ct. has anyone been given suboxone for pain managment. I here thay are givin this out now I tryed 2yrs back and wow what a head ach It gave me.Is it still like that let me no email me at [email protected]

A head ache like that is prolly due to Hypersensitivity to Naloxone... Check out naloxone hypersensitiity on google.. u;ll prolly find this was the case ...

 

[jamesBrown]

I live in ct. has anyone been given suboxone for pain managment. I here thay are givin this out now I tryed 2yrs back and wow what a head ach It gave me.Is it still like that let me no email me at [email protected]

Buprenorphine IS used for pain management but only in tiny doses. It is marketed under tha name "Tamgesic". Its just bupe with no nalaxone in doses ranging from 0.2- 0.4 mg's. So you theoretically COULD use suboxone for pain management but you should only take doses of less than 1 mg.

And yes, suboxone can cause headaches in high doses. Its the #1 side effect experienced when they did the studies. Not sure exactly why it causes headaches but they definitely DO happen.

 

[homeydontplaythat]

the naloxone causes headaches

 

[jamesBrown]

the naloxone causes headaches

Ive always wondered if this is true. Im not saying its not true but since the bupe outcompetes the nalaxone for your receptors, how could the nalaxone become activated in your brain to cause headaches? I think it is just as likely(if not more likely) that the bupe causes the headaches. Many opiates I have taken have caused headaches, especially in the higher doses. And since most people only feel the headaches at a high dose of suboxone(and since bupe is around 40x's more potent than morphine) I would think it is very likely that its the bupernorphine thats causing the headaches.

 

[stray cat]

what about at the lower doses where the buprenorphine doesn't fully cover your receptors? (i.e., those doses where its metabolite norbuprenorphine can give euphoria since receptors not fully covered by bupe). at those levels, then, couldn't stuff like naloxone still have an effect on those receptors not covered fully by the bupe?

i understand that most people get the headaches at the higher doses, so this isn't necessarily just a naloxone/headache question. i've wondered about this before... if at lower doses people get euphoria bc buprenorphine is not fully covering the receptors, thereby allowing its metabolite to do so and producing euphoria, couldn't other stuff hit your receptors at lower doses too?

 

[jamesBrown]

what about at the lower doses where the buprenorphine doesn't fully cover your receptors? (i.e., those doses where its metabolite norbuprenorphine can give euphoria since receptors not fully covered by bupe). at those levels, then, couldn't stuff like naloxone still have an effect on those receptors not covered fully by the bupe?

i understand that most people get the headaches at the higher doses, so this isn't necessarily just a naloxone/headache question. i've wondered about this before... if at lower doses people get euphoria bc buprenorphine is not fully covering the receptors, thereby allowing its metabolite to do so and producing euphoria, couldn't other stuff hit your receptors at lower doses too?

I understand your question......

but when you take a small dose leaving some of your receptors open, then the metabolite norbupe should cover atleast almost the rest of the receptors because it has a higher binding affinity than nalaxone does. This should leave little to no receptors left for binding....and if there are any left open still....it would be a very minimal amount, probably not enough for nalaxone to actually have any effects comparable to the bupe/norbupe....

but...it shouldnt really matter anyway, because the nalaxone isnt absorbed when taken sublingually. And thats how most people take the drug, and consequently, thats how most people take the drug that complain of headaches. So how would you explain that? Because the headaches were a common occurence when they did studies on suboxone and they were only giving it to the test subjects sublingually and in higher doses(>4mg's). And like I said...the nalaxone is inactive especially when taken SL.

Also...the half life of nalaxone is only 1 - 1.5hr's.