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Bupe Suboxone/Buprenorphine FAQ and Megathread v.1; 2007 - 2010

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bow-viper1 said:
Although I can't answer your question, I wanted to address this statement.

I find it fascinating that a 2mg or 4mg dose of Suboxone produces the same or better effects than a dose of 8mg or more. Because I, and several other people have been reporting the same thing for some time now.

I know the general consensus is that the naloxone in Suboxone is rendered ineffective by buprenorphine's higher affinity, but I can't help but think that there is some sort of plateau with Suboxone, after which the naloxone starts having affecting the experience. I just can't think of any other reason for this.

Does anyone have any more information on this subject?

^^ Gonna do abit of researching myself. Can't get it out of my head now, and I wanna agree w/ the person who mentioned hearing or reading that anything over 8mgs is a waste. I'd say that's true. About the "plateau" of Subox? I'm betting you're right on the money. This is why in an earlier post, after reading that an individual was taking "4" 8mg tabs daily (even prescribed I believe!?)
I just couldn't believe it. As a Sub taker, I have on occassion taken a 1/2 tab
in the afternoon, after my normal 8mg dose in the a.m., and wow, it's so good!
But then this other stuff doesn't make any sense, you follow? With a ceiling(sp)
of 8 already in my system, and I mean for a year now daily, how/why could an
additional 3-4mgs 6hrs later produce that jazzy energized feeling??
I add that only as insight into this mind boggling question about the lower doses. It throws yet another monkey-wrench into the puzzle. All I know is that
Sub is NOT supposed to get a person "high" (=euphoria), but it sure comes close at those lower doses we've spoken of, and hey...why lie? I'm an f'ing dope fiend and I wanna feel it!!!! Legally on top of that!
Peace out...%)
Click to expand...
 
bow-viper1 said:
Although I can't answer your question, I wanted to address this statement.

I find it fascinating that a 2mg or 4mg dose of Suboxone produces the same or better effects than a dose of 8mg or more. Because I, and several other people have been reporting the same thing for some time now.

I know the general consensus is that the naloxone in Suboxone is rendered ineffective by buprenorphine's higher affinity, but I can't help but think that there is some sort of plateau with Suboxone, after which the naloxone starts having affecting the experience. I just can't think of any other reason for this.

Does anyone have any more information on this subject?
Click to expand...

this is just my opinion but maybe this has to do with buprenorphine's partial agonist AND antagonistic properties. cause i know bupe overpowers the naloxone everytime cause its its obvious higher affinity for the receptors.
 
Okay well, here we are Bupe isnt working for me, it has in the past but it is not now, no matter what dose, or dosing multiple times a day I DONT STAY WELL!! So, I am transferring to methadone (I know I know stupid me but hey I plan to be on maintenance for quite some time if not the rest of me life i keep going round and round with addiction and cannot win the battle of sobriety even though I want to be clean).

Anyway my question is I know that when switching from Methadone to Suboxone you have to be at less than 30mgs a day of methadone and wait two days after your last dose of methadone to prevent precip. wd's. I am wondering IF you have to stop the suboxone before starting the methadone? And if so HOW LONG do i have to wait before I can take my first Methadone dose?

With those questions in mind i ask for a few things, Please no bullshit about me going to Methadone its my choice, and second i dont want to hear the less is more or anything like that because I have tried everything from .5gs upto 32mgs to stay well and NONE of the doses would hold me all day... Thanks to everyone in advance...
Peace Love and Light
Mat
 
Breaking through the Great Barrier reef of....Suboxone?

Ok, I know that many people would love the help of Suboxone and only an asshole aka addict would abuse it....but has anyone had success breaking through the barrier of Suboxone WITHOUT IV'ing. My friend suffers from a rare form of Parkinsonism (not full blown Parkison's but he has a pretty gnarly shake) and he wants to actually get off about once every 3 months despite being on Suboxone maintainence at 8mg a day.

How long does he need to wait to get high off a dose of Oxycodone intranasal? He states that even 2 80mg pills around the 24 hour mark have only left him well before and with no sign of euphoria. I feel this seems to show that he is either sensitive to Suboxone or it is incredibly strong.

If anyone has any advice for breaking through Suboxone (minus the needle) it is welcome.
 
SUBOXONE IS INCREDIBLY STRONG.



Check the suboxone mega-thread, its for answering questions like this (look in the stickies if you can't find it).
 
I have gotten REALLY high from a large shot of H, just 12 hours after using 14mg Subutex.

I'm sure if I had smoked just a little more then it would have been the same.

Everyones different, this guy obviously just eeds to wait a little longer. If he was to just wait until he started feeling withdrawal, then he bound to feel Heroin/oxy properly.
 
If he is taking Suboxone daily, his tolerance is going to increase to very high levels.

He will be able to get high if he stops taking the bupe around 48 hours before doing the dope, but he will really need to be careful with the dose because he will most likely need a nice amount to get him high, but he also needs to be careful about taking too much and ODing.
 
DopaMan said:
How long does he need to wait to get high off a dose of Oxycodone intranasal? He states that even 2 80mg pills around the 24 hour mark have only left him well before and with no sign of euphoria. I feel this seems to show that he is either sensitive to Suboxone or it is incredibly strong.
Click to expand...
That is because buprenorphine has a half-life of approximately 36 hours. He may as well throw 160mg of oxycodone out the window, because that is what he did by taking it only 24 hours after his last dose of Suboxone.

He needs to wait until he is feeling withdrawal symptoms from the Suboxone to take his oxycodone. It is different for everyone, but that means that he needs to wait between 36 and 72 hours. Personally, I fit in the upper part of that range. I need to wait about 72 hours before I can get close to the full effects of another opioid.

It is very easy to tell when it is safe to take his oxycodone - all he has to do is wait until he is starting to experience symptoms of withdrawal. And once they start, the longer he can hold out, the better it will be.
 
The whole wait until WD thing is very helpful, but like my friend said "easier said than done!" He stated that he feels somewhat "crappy" at the 24 hour point, but it is nowhere near WD. Actually he stated that he was able to stay stable for about 72 hours from his last dose of Suboxone (although at 16mg vs. the 8mg he is on now), so he may be at the end of the spectrum also. Thanks everyone for the input. It seems that he may just give up on the idea which is a good thing. Looks like Suboxone's blocking mechanism is very useful when it comes to non IV users/addicts.
 
When I quit suboxone after a year straight, then tryed it again (big mistake). It got me super super high, litterly I would be nodding my ass off so hard. Then one day it all went away, I had to withdrawl from that, and dexedrine. It sucked.

Still there's somthing I miss about suboxone and the way it helped me. It can help you alot...
 
yep, I miss suboxone a lot.

the stability is what I miss mostly. knowing that if you're trying to stay clean for awhile or that if you've been bad and binged for a few days (or weeks lol) you've got that safety net so you won't be sick when you run out of money is awesome.
 
I got my hands on a couple of suboxones. I could crush it up and snort a line, and catch a opiate buzz.

How long can I do this for? Is it even possible to get addicted to suboxone?

-PLUR
 
Candy_Raver said:
I got my hands on a couple of suboxones. I could crush it up and snort a line, and catch a opiate buzz.

How long can I do this for? Is it even possible to get addicted to suboxone?

-PLUR
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Oh yes it is. I know someone who got hooked on taking them illicitly. He had maybe a pill every week! but still used for long enough that he suffered, mild, but true withdrawals.
 
Candy_Raver said:
I got my hands on a couple of suboxones. I could crush it up and snort a line, and catch a opiate buzz.

How long can I do this for? Is it even possible to get addicted to suboxone?

-PLUR
Click to expand...

If you dont have any opiate tolerance then it'll get you high.... Technically everyone who uses them for maintenance is addicted to them, shit i know i am. Honestly I don't even know why you would take them recreationally go get a real opiate and leave this one to the people who actually need it. :p
 
I don't have access to real opiates everyday. Suboxone is all I have and by crushing it up and snorting it I carch a mild buzz from them. They are not as good as real opiates, but I just want some sort of high because I don't have access to real opiates everyday.
Dosn't really matter what type of drug if its out there I will abuse it, I like to be high everyday.

-PLUR
 
Will that stuff raise up your opiate tolerance? I have high tolerance to pretty much every class of drug, and don't want my tolerance being ruined by this.

-PLUR
 
What the hell??

I snorted 1/2 a pill and was supposed to catch a buzz. 15 minutes later I got really nauseated and puked TWO times!

Is this drug supposed to make you puke? Whats wrong with this drug???:X
I just wanted to get high!!

-PLUR
 
^
Probably took too much. Buprenorphrine is very strong, especially if you don't have a tolerance.

Do you have pills that say N2 or N8 on them?
 
Candy_Raver said:
What the hell??

I snorted 1/2 a pill and was supposed to catch a buzz. 15 minutes later I got really nauseated and puked TWO times!

Is this drug supposed to make you puke? Whats wrong with this drug???:X
I just wanted to get high!!

-PLUR
Click to expand...

Hmmm maybe because it's not meant for getting high? ever think of that?
 
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