🌟🌟 Social 🌟🌟 Rectify's molecular poetry thread

[Rectify]

PATAGONIA
1-dimethylamino-1-(3-methoxyphenyl)--4-(4-hydroxyindole-3-yl)cyclohexane

 

[Smyth2]

PATAGONIA
1-dimethylamino-1-(3-methoxyphenyl)--4-(4-hydroxyindole-3-yl)cyclohexane

Lednicer already elucidated that oxygenation into the meta position is consistent with opioid receptor antagonists.

BDPC - Wikipedia

en.wikipedia.org

 

[Rectify]

Okay, That Sounds Undesirable.

 

[Rectify]

New Order, "Here To Stay."

Who is this man that follows me?
This blue-eyed boy who wants to be
This worthy cause of humankind
This pawn set up by time

[Chorus]
Like a bright light on the horizon
Shining so bright, he'll get you flying
He'll drive you away, he'll drive you insane
But then he'll remove all of your pain

Like a bright light on the horizon
Shining so bright, he'll get you flying
He'll get you flying, he'll get you flying
He'll get you flying, flying, flying

[Verse 2]
This open book yet to be read
This second look, this leap ahead
The hope I held inside
With you, was kept alive

[Chorus]
Like a bright light on the horizon
Shining so bright, he'll get you flying
He'll drive you away, he'll drive you insane
But then he'll remove all of your pain

Like a bright light on the horizon
Shining so bright, he'll get you flying
He'll get you flying, he'll get you flying
He'll get you flying, flying, flying

[Bridge]
We're here to stay
We're here to stay
We're here to stay
We're here to stay
We're here to stay
We're here to stay
We're here to stay
We're here to stay

 

[4DQSAR]

Cebranopadol is a rigid BDPC derivative. The latter a metabolite. I don't know but would guess that the latter has lower MOR affinity given that N-desmethyl BDPC demonstrated that fact.

 

[Smyth2]

It looks encouraging that cebranopadol might get approval soon based on the results of the clinical trials.