As a former addict who chased the immodium dragon for about a year, I have a few things I wanna say:
1. Lope cures 95% of withdrawals at doses of 14 - 20mg, so higher doses are just foolishness (I took WAY higher doses)
2. Lope leads to physical addiction and suboxone-style withdrawals upon cessation from doses of 30mg+ continuously
3. Jumping from 250mg of lope a day was the worst withdrawal of my life, and I've had plenty of withdrawals
4. Lope fucks with your ability to orgasm / sexual drive more than any other ope I know
5. Lope becomes progressively more mood lifting with continued (not daily) use for a few weeks, but then it follows the standard tolerance/loss of effects pattern
There, I'm done.