Shiznik you know those links you posted are from ingestion of 125mg of MDMA.. the same link also goes on to say that high doses of MDMA causes damage to neurons through oxidative stress.. maybe you should read your links more carefully before posting them to prove your point in an argument your clearly losing.
You're only kidding yourself if you think I didn't read through the entire thing. The "contradiction" your detective work found is in the next paragraph... Did you really think I didn't get that far? I didn't "post links to prove my point", I posted links where I had previously learned about what I was writing because someone asked me to.
What I wrote in response to you had two parts:
1.) Neurotoxicity does not necessarily occur the way you suggested it did (being that dopamine "destroys serotonin uptake receptors due to its oxidization") and
2.) Permanent loss of magic is not real.
You seemed to have thought that I was claiming MDMA does not cause damage to your brain, so you decided to call me ignorant (though you are the one calling your little dilemma "magic loss") several times and go on to prove that damage does in fact occur. Of course it does...
I'm actually of the opinion that MDMA is quite a bit more neurotoxic than we all give it credit for. I think it leaves a lot of us who have abused it with our fair share of problems. None of which, however, are a permanent intolerance of the drug. Like I said, I have seen studies where this axonal damage is reversible. New serotonin axons have shown to grow in place of the destroyed ones. It even suggests that in one of your quotes you took out of context in attempt to make me look stupid ("recovery from MDMA neurotoxicity is associated with apparent sprouting and regrowth of axons ").
Neuronal damage is a permanent thing..
But sometimes the user has abused it for too long and no matter how long a break they go on their brain will not fully heal..
Where are you getting that information from? I've not read that anywhere. Within each of the links I posted there are examples suggesting the opposite of what you claim.
This is an example.
This is "a large German study looking at the brains of people who had used approximately 800 tablets (on average) of 'ecstasy' over their lives"..."study findings indicate that continued regular, heavy ecstasy use lowered serotonin transporter availability, but that
formerly regular, heavy ecstasy users no longer had lower serotonin transporter availability." Like I said, you'd likely be left with your fair share of problems, but nothing suggests the drug would simply stop working.
I hate to paraphrase findings of a complex study like that but you've made this a contest. I don't claim to be an expert in this field, quite the opposite in fact, but from what I have read, the conclusion that I have drawn is the exact sentiments of many others: this permanent "loss of magic" stuff is just a buzz term only thrown around in the United States that holds no scientific ground. In fact it's just stupid misinformation. The longer people talk about it on this forum, the longer new ecstasy users are going to worry about it, and when that starts to happen, it becomes a reality for them. Mind over matter.
![:\](https://bluelight.org/xf/BL_Images/Orig_Emoji/wrygrin.gif "wry grin :\")
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