Opioids O-DSMT Megathread

[knock]

So I have a gram of O-Desmethyltramadol coming in the post tomorrow. As someone with no history with opiates (apart from a couple of goes with kratom), what would be the safest way to approach this? Is it the sort of drug you can redose on, or is it very much just dose once and leave alone.

Also to avoid W/Ds, how much time should I leave between use?

After allergy testing you might start with 40mg plugged. I was also by and large unfamiliar with opiates when I first tried this. I started sniffing but soon discovered it's a waste.

My current dose is 50-60mg plugged but I think I have a little bit of a tolerance. Oral works similarly to plugged but takes longer to kick in.

You can redose but beware the opiate vomits! Not that they are unpleasant, but they might surprise you. I will vomit on 50mg + 50mg redose. I don't think redosing presents much of an imminent danger to physical health, but watch combos with other CNS depressants. Having said that I've combined with moderate quantities of alcohol on many occasions (up to 2/3rds of a bottle of wine [actually on one occasion two bottles of wine]) without issue.

The need to redose is not really significant as one dose last for hours. Just get your inital dose right.

Be careful this is seductive, I have found myself taking it more and more often as there seems to be no major downside, but I imagine when I run out I will see one. Better reorder! I try to leave a day between dosing, preferably two or three. I'm not saying this will guarantee you avoid w/ds, just what I'm currently doing. My original intention was to use once per week but that rule was torn up and stamped on quite quickly.

The elimination half life is 9 hours, I imagine the body builds tolerance faster the longer it is exposed to a substance, make of that what you will. if you were to dose 50mg twice a day then there will be an active amount in your body all the time, this is bound to lead to tolerance and subsequent w/ds, although they may be very mild.

 

[JJ-180]

O-DT seems to have a relatively long half-life. 2-3 days off is the minimum , as this stuff has quite serious addiction potential.

 

[foolsgold]

i got a 250mg at the weekend after a weeklong stim and mxe binge and it was a beautiful way to come down next day tho christ i had the shits something rotten . just vapped it wasted abit to much as i was so far gone i wasnt thinking straight . just must remind myself its not hash im doing and i could end up messing up big time

 

[Albion]

Well this drug is beautiful. I absolutely sympathise with Knockando's sentiment that it is extremely seductive. I started off with 50mg rectal, followed by another 50mg an hour later. The high was intense, and I got the vomits pretty much all evening. Dehydration is a real issue with this, as the inability to hold down any liquids coupled with the expulsion of all liquids really left me worse for wear. I suppose first time, I had no idea what my nausea threshold would be.

I noticed quite significant time dilation. The high itself lasted for about 5-6 hours but it felt like 12. Nodded pretty heavily when into the early hours. I noticed that my breathing became very shallow, as the high got more intense. Overdose seems a very real and dangerous prospect with this. It's probably the scariest legal RC I've ever come across.

 

[Scarecrowm3]

Apologies If this has already been mentioned but extensive googling has turned up very little, close to nothing. Very little Opiate experience, no tolerance. Few times I've done Codeine, raw opium once, enjoyed so so much.... sigh...
Anyway, would smoking O-dt in a roll up with tobacco (no filter) and maybe a little cannabis be effective (chasing is not an option for me in the situation I will be trying O-dt)? And at what dose? Again apologies, as I type this it seems a stupid question but I purchased the smallest amount possible and for fear of addiction refuse to purchase more for at least a few months and therefore don't wish to waste a whole dose.
First post! woop! be nice
Scarecrow

 

[PoppyLlama]

I got scammed on some of this shit on the internet and lost like 200 bucks... fuckin stupid stupid it sucks. I really just wanted to try this chemical I have bad chronic pain and just want to be able to live an active life and not be in total pain all the time.

 

[Lewis_Tollani]

Is this much better then regular tramadol? I have never tried it and it is illegal in the country where I live and I have no source that sends it within the borders so ordering it is a bit of a risk for me. Not a very large a risk because it is still within the EU but still.

Is it worth the risk because tramadol is easily available? But if this is much better I'm inclined to gamble a little.

 

[lurching]

insufflation seems pretty potent to me, at least as potent as taking it orally.

i much prefer it to regular tramadol. less tweaky and more sedating. it's one of the nicest opiates/opioids i've had (have experience with codeine, kratom, hydrocodone, talwin, morphine and heroin).

 

[adder]

What relevance does partial agonism have to ROA? I don't understand and I would like to know.

Absolutely none. I was answering the question if O-desmethyltramadol would kill dopesickness. The ROA doesn't matter but let's be honest, if OntarioGuy shoots up some 4,5-epoxymorphinan, then he won't go for taking M1 orally.

 

[knock]

insufflation seems pretty potent to me, at least as potent as taking it orally.

Weird, I've had to shovel it up my nose (150mg+) to get to the same place 50mg can get me orally!

Absolutely none. I was answering the question if O-desmethyltramadol would kill dopesickness. The ROA doesn't matter but let's be honest, if OntarioGuy shoots up some 4,5-epoxymorphinan, then he won't go for taking M1 orally.

I think I see what you're saying: as it's (probably) a partial agonist it (probably) won't help with dopesickness so it seems silly to take the risk of IV'ing?

I started off with 50mg rectal, followed by another 50mg an hour later. The high was intense, and I got the vomits pretty much all evening. Dehydration is a real issue with this, as the inability to hold down any liquids coupled with the expulsion of all liquids really left me worse for wear. I suppose first time, I had no idea what my nausea threshold would be.

When I have puked, it's been once in a "session". A few hours in, throw my load, then back to whatever I was doing. I suspect your sustained puking was down to you jumping in the deep end on your first dose! I did say start with 40mg I don't puke at all if I keep my dosing below around 80mg. 100mg plugged seems guaranteed to do it. I have not puked when I have not plugged, but I've seen a friend puke loads from sniffing, so individual physiology must play a role.

I noticed quite significant time dilation. The high itself lasted for about 5-6 hours but it felt like 12. Nodded pretty heavily when into the early hours. I noticed that my breathing became very shallow, as the high got more intense. Overdose seems a very real and dangerous prospect with this. It's probably the scariest legal RC I've ever come across.

I hesitate to say it's safe, but the more I've played with this the safer it seems (addiction aside). That might be tolerance speaking. There's a guy who IV'ed 2 grams and didn't think anything of it. It's healthy and wise to show respect for opi*s though.

 

[FlyBoy81]

I got scammed on some of this shit on the internet and lost like 200 bucks... fuckin stupid stupid it sucks. I really just wanted to try this chemical I have bad chronic pain and just want to be able to live an active life and not be in total pain all the time.

That sucks man...I want to try this chem, but I don't want to get scammed as well.....

 

[adder]

I think I see what you're saying: as it's (probably) a partial agonist it (probably) won't help with dopesickness so it seems silly to take the risk of IV'ing?

That's what I meant. And yes, probably or even maybe. But even taking it orally could be risky then. Well, I've witnessed a psychiatrist prescribing me tramadol for morphine/levorphanol addiction but I guess he totally didn't give a damn whether it'd help or not as the dose was totally inappropriate (a taper-down schedule for 160-180mg morphine i.v./40mg levorphanol i.v. started with 50mg of tramadol 4 times a day, really "ha ha"...). However, I took 1600mg in total (I'm also addicted to clonazepam), I didn't feel a thing, it didn't worsen my withdrawal either and I could easily "heal myself" with morphine without waiting. I don't really know then about this "partial agonism" thing.

IMHO It's just a very low affinity (various sources give different values for MOR, I've seen 2.4µM (Gillen et al., 2000), it's definitely >1000nM anyway. It may be a full agonist but both tramadol and its active metabolite M1 have lower binding affinity (3.4nM in case of (R)-(+)-M1 and 240nM in case of (S)-(-)-M) than morphine so morphine would force out both of drugs. Although there's one thing I found interesting about R)-(+)-M1, its relative intrinsic efficacy was 1.23 vs. morphine's 1.17. But the same table also lists MOR affinities of both drugs with morphine's being 0.62nM and R)-(+)-M1's only 3.4nM.

I've got the file backed up on my flash memory. Google "Tramadol_Qs_As" and that's it in .doc format.

 

[knock]

^ nice read thanks!

 

[InterzoneAgent]

Interesting to see withdrawl reports coming in. I haven't been here for couple of weeks and ran out of this stuff few days ago. My habit was pretty much the same as with the user JJ-180 and i can pretty much agree what others have said about O-DT WD's. I used it for about 1,5 months, basicly daily apart from couple of short breaks. At start my dose was about 150-200 mg's and on the last days i did anything from 350-500 mg's. ROA was always plugging.

First night of WD's was pretty hellish but apart from that they are quite mild (that's not to say they are easy to endure but compared to to using oxy or fent for the same time they are piece of cake). The withdrawls seem to be (hope so) pretty short, right now i'm feeling pretty good apart from mild restlesness, leg aches and lowered treshold to cold. It's been almost 72 hours now´since last dose. The insomnia is not that horrible either. However last evening i was feeling really good but as soon as i went to bed and tried to sleep the wd's kicked in again and i could sleep only for very short periods. This happens to me always, the nights while wd'ing are thousand times worse than days. As soon as i try to sleep and close my eyes i get extremely anxious, the aches get worse and i can only roll desperately around in bed trying to find a comfortable position even for just a few seconds. Insomnia is always really bad for me and benzos don't help it. Anybody know why does it get always so much worse when i'm trying to sleep while wd'ing.

 

[InterzoneAgent]

okay it's 96 hours now since my last dose and i'm feeling much much better. Got some good sleep last night and now i'm only feeling somewhat cold, tired and anxious. Great thing Probably order some more soon and fuck it all up

I should mention too that my last dose was only 200 mg that i had left, days before that i usually took around 450 mg's. Don't know if that eased the wd's any. The wd's kicked in fast after 13-14 hours when taking the smaller dose, usually it was only after 24 hours.

 

[Mugz]

I had a week of use when I had 500mg of it not long ago, used it every day but one during that week but not heavy use each day.

Until the last day I was only doing 50mg doses which all produced great anti depressant effects and felt quite nice, on par with low dose codeine perhaps.

The best day was the last day that I used it when I felt comfortable trying a higher dose after experimenting with low doses.

50mg snorted followed by another 75mg an hour or so later had me in a state lovely opiateness, another 75mg a couple of hours later and it was even better. I don't have much experience with "real" opiates but have to say that this felt much more like a true opiate than tramadol ever did. Think I redosed once more to finish of the bag too.

I got a really nice nod from it after the initial mild opiate stimulation, found when redosing it would wake me up from the nod again initially and I would be really sociable and happy and euphoric, then I would go back into the nod.

There was some trouble sleeping without adding in a benzo.

The next day I felt quite rough and really wanted some more, I will use this sparingly in the future as I can see the potential for addiction and problematic use.

Also see the great possibilities that this could have as an antidepressant at low doses, 20mg snorted lifted my mood greatly without getting me high.

I know my doses might seem low to those with an opiate tolerance but I think if you have no tolerance then this is definitely worth it.

 

[Scarecrowm3]

50mg Intra-nasally
Opiate Naive
Male
Medium Build.

First trip report; any pointers will be appreciated so I can be a valued member :D

21:00, Mild burn, sort of a gentle sting on the nose, certainly not the worst thing to throw up your hooter, certainly not the best.
No real euphoria, very relaxed and dopey after an hour, subtle effects have you laying out surfing the internet without a care in the world. Found myself feeling fairly normal and sober except for the occasional giggle at things that would normally make me smile, and no concerns about things that normally bug me (washing up, getting stuff ready for the morning etc)
23:30, decide to get some sleep, fairly dissapionted, was hoping for something a little more noticable. Sleep came on quickly.
-then came the fun bit-
Waking up at 6:00 I felt good, very good, slightly groggy but not more than normal. Getting up and walking to the kitchen I feel, not tired, but certainly not awake, feel slightly dizzy and sick but 10 mins of sitting in an armchair and slowly eating breakfast fixed it. Getting on the bus I started to nod, it was every nod description I've read and more! drifting between hanging with friends at the beach and startling myself that Im acc on a bus! Passed it off as tiredness to the one friend who noticed and allowed myself to nod some more. (note that I could sorta slap myself out of it 90% of the time) this nodding happened whenever I let my thoughts drift, Id wonder what Id do that afternoon and suddenly find myself waking up. This continued till 10:00 that morning with me holding onto conciousness during conversation and nodding when it went quiet. Great fun, but need to plan better considering it lasted near 12+ hours. Sorry long report but hope I covered all aspects of what might happen to a guy with no tolerance. :D

 

[knock]

I'm surprised you were still nodding after a night's sleep! It is long lasting though isn't it.

Welcome to Bluelight and it would be good if you would try not to slam your front door whenever you come and go, it makes the whole building shake! (check my location )

Oh yeah, there is a dedicated Trip Report forum but people often post mini reports in here too. The TR forum has a certain standard for report format and content, but I think yours would meet them just fine. Maybe space out your "timeline" a bit so it's not all one block of text, to help readability.

 

[az5000]

Got some more of this lovely stuff coming in the post tomorrow, looking forward to a nice weekend! In terms of bioavailability, which route is best? I prefer to stick to oral or sublingual, but am willing to try snorting or rectal. Just don't want to waste it if it's not worth the effort!

 

[knock]

For me plugging, as for most things, seems best, but oral really isn't that far behind, takes a wee bit longer to hit you. Full stomachs do not help.

Sniffing doesn't work too well for me but I know it works for others. I think there must be something wrong with my nose, I have to sniff double what I would stick up my bum, so I don't do it.

Haven't tried sublingual, can't see it being better than plugging. Once you're into the swing of plugging other non-injection ROAs just seem amateurish!* The only time I snort nowadays is with ketamine or in polite company.

[*why do I love plugging so much?
- reliable, rapid absorption. It's easy to make sure the rectum is empty before plugging, you either need a shit because it's full so you excrete, or you don't because it's empty so you plug. Food can hang about in your guts for fucking ages interfering with uptake. Stomach acid can destroy some drugs.
- seems healthier than any other ROA. Smoking damages your respiratory system. Sniffing can fuck up your nose and give you infections. Injections require sterility. The arse hole is built to deal with toxic waste! Not saying it's risk-free, but it seems best.
- bypass first-pass metabolism. Obviously whether this is a good, bad or neutral thing depends on the drug.
- get to play with paraphernalia.]