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Opioids O-DSMT Megathread

I suffer from RLS (restless legs) - nothing to do with opiates, I've had it all my life - and when I'm on the o-desmethyltramadol it is alleviated.

However after dosing up to 100mg every two or three days for a couple of weeks, and then stopping, I am now getting the same feelings in my arms. I have never had this before. It's five days since I last dosed and it's still there. It's not constant but it's there 80% of the time.

Could this be withdrawal symptoms from what seems to me like quite moderate use? I hope so, and I hope it goes away! It has made sleeping very difficult on a few nights.
 
^ it seems unlikely that dosing only 100mg every two or three days for a couple weeks (so like a total of around 6 or 7 doses?) would cause withdrawal symptoms. However, If you recently kicked an opiate habit then this small amount of use could send you back into withdrawals.

If your o-desmethyltramadol has some tramadol in it then the snri properties could possibly cause some lasting stimulation, but I find it unlikely this would continue for 5 days after your last dose. Exercise may help to alleviate some of the restlessness. I hope you feel better!
 
I have 3 grams of this stuff coming. Any word on how the new batch is supposed to be as far as purity?

From all the research I've compiled and reports I have read, I am expecting from 1/5th to 1/3rd as strong as Morphine.

I will test various ROA's to try an establish some BA information about this compound. Very promising reports of IM/IV use without complications, I will, of course, be micron filtering anyways.
 
After a little testing it appears that the oral bioavailability is somewhat lower than insufflated, but this is based on only a handful of experiences. For those not inclined to inject their drugs, plugging or snorting sounds like the way to go.
 
Based on the molecule when viewed in comparison to other strong opiates... it looks like the BA is not going to be as low as the oral BA of Heroin or Dilaudid, but it is certainly not like an oxycodone where it is 90% +. My estimate without having done it is that it will be around 40-60% orally.

I hope to confirm this soon.

Again, that is an estimate. Maybe people who have experienced it can weigh in on this???
 
I always use it orally, as the drip is too bad, tastes awful and i've never plugged. Dont want to get into pinning regularly either. I use doses of up to 600mg at a time, and i havnt pinned for a while so cant compare but 150mg pinned gave a daaaaamn good rush and a nice nod a while ago
 
If you are equating those two dosages, that would mean it has an oral BA on the order of Heroin or morphine... interesting.

Anyone else have equivalency approximations?

This could actually be really useful as far as harm reduction goes in establishing some approximate numbers for this substance FWiw.
 
I've stopped using it now as I was taking doses that were too high and it was resulting in me feeling physically sick a lot of the time.

However, I found that 100mg plugged (dissolved in 10ml warm water and administered via a syringe, without the needle) gave a fantastic effect.

Insufflation and oral (in gel caps) were my standard ROAs as they were easier.

I couldn't say which was most effective as I was pretty high for quite some time. It all kind of blurred into one after a while; I was either feeling an effect or I wasn't, and I was also experiencing quite a bit of nausea. Hence the stopping.
 
^ it seems unlikely that dosing only 100mg every two or three days for a couple weeks (so like a total of around 6 or 7 doses?) would cause withdrawal symptoms. However, If you recently kicked an opiate habit then this small amount of use could send you back into withdrawals.

If your o-desmethyltramadol has some tramadol in it then the snri properties could possibly cause some lasting stimulation, but I find it unlikely this would continue for 5 days after your last dose. Exercise may help to alleviate some of the restlessness. I hope you feel better!

Thanks for your response, and your concern, I do feel better today - BUT I dosed last night as I had to sleep to ensure I was fresh this morning for something I had to do. Having said that I didn't feel too bad at all before dosing and I was really after the recreational effects. I don't really notice any stimulation with this, I'm not 100% sure of course but I trust my vendor and I don't think this is adulterated.

I have to say I am quite enamoured of this stuff. It makes me a happier and more sociable person. I dosed 50mg oral at my parents house, typically I find being there a bit stressful, I love them but they have hypocritically high standards, and they're old, a bit boring and a bit stifling, like a lot of parents I suppose, and it's just difficult to relate to them. This chemical made being there easy and at a low dose there is nothing outward for them to notice (other than me being relaxed and happy).

It works so well for my chronic debilitating neck pain. I can get stuff done when I'm on this. And I find it helps in creative thinking. I dabble in digital music, programming synthesisers and so on, and last night I lay in bed working out various different ideas to try; I would imagine sounds and try to work out how to synthesise them and I would come up with nice ideas to try out. Normally my mind is agitated with worries and plain nonsense, I think I'm slightly OCD or something, but I was able to focus without effort and really enjoyed it.

Plus it just feels really nice ;)

I have used alcohol to an unhealthy extent all of my adult life (I'm knocking on 40). I wouldn't call myself an alcoholic, the quantities were never that large - typically a bottle of wine a night - but it's been a daily thing for me, with more or less frequent binges, and lately I've been able to reduce my alcohol intake significantly by using other intoxicants, mainly Methoxetamine but also o-desmethyltramadol. My working theory has been that it's healthier to cut down the alcohol and replace it to some extent with "cleaner" drugs which are less likely to give me serious health problems. In addition to alcohol abuse, bowel cancer runs in my family, which is a concern, as there's a causal relationship. So I am imagining that this drug could fit into some kind of varied dosing schedule.

So what's the downside? As I have only positive things to say about this, I do have the urge to use it more frequently. As an opiate/opioid newbie, I don't really know what my limits are with this. I am concerned about dependence. I'd like to continue using it two or three times a week. Am I setting myself up for a fall? What kinds of limits should I set for myself?
 
Run out of my last of this, got enough to see me through today, then after today i'll have a week or so of naasty withdrawals. I'll keep yous updated :)

Might try plugging today since its my last bit, how do you dissolve such a large amount in such a small bit of water? And do i just go up to my local pharmacy and ask if they sell oral syringes?
Cheers
 
yeah, either ask for an oral syringe or a mixing syringe... they are both 3-10mL with a leur-lock tip, but the mixing syringe will come with a screw-off needle.

O-desmethyltramadol is extremely soluble. I think I read 250mg/mL which is pretty damn high.
 
Is a mixing syringe suitable for IM/IV shots? And how much do they cost in the UK & do they ask questions? Got a vial of ketamax left which i really want to try IM!, do you push the needle all the way into the muscle for IM shots?

Sorry, a bit off topic haha

I'll be plugging or shooting the o-dmt, see which is more effective as i've just been bombing for the last while and wouldnt mind a decent rush! Not a huge needle fan though
 
I must say I was impressed with this compound. 100mg insufflated provided nice effects. The comeup was gradual, and a bit stimulating at first, but settled nicely into a warm, pleasant, opiate high. It also lasted surprisingly long. Residual effects could be felt well into the next day(I dosed late in the evening).
 
Plugged about 70mg in the end, I feel it but its not that strong, just smoked the remaining 20mg and its starting to get a bit stronger, going to watch fear and loathing with a joint now, happy days! :)

Next time im defo gonna go for 100mg up the poop shoot straight off the bat


So O-desmethyltramadol can be smoked? Like vaped off of foil?

And if so what dosage would you recommend for an individual with no opiate tollorence.
 
Hey everyone, I sent PM's to most of you asking to contribute data and observations to this thread.

Unfortunately, in many of the PM's the hyperlink broke for some reason, I apologize. If I didn't PM you, please visit the thread - it is a survey on subjective experiences designed to get ballpark figures for bio-availability. I will have access to blood plasma analysis later in the summer, so I will follow up with my (personal) levels from that, but I feel as though the data collected from you guys will be more accurate than testing one person, as long as there is a big enough sample size.

Thanks for your help. Again, here is the thread.
 
Yes, you can smoke O-DT. I tried it...once.It tastes absolutely disgusting, to the extent that by the second or third lungful, I was retching. Which is a shame,because when it melts on the foil it looks just like really high quality light Brown.
 
Can anybody who IV's this stuff tell me how it compares to IV morphine or IV oxycodone?
Do you think shooting a good dose of it would kill the dopesickness of someone who usually IV's 100 mg's of morphine 2x daily?

This stuff has had me interested for a while now....

It's highly possible it is a partial agonist so I wouldn't risk i.v.'ing M1 until I see some serious comment on this. At the moment you're like a guinea pig, really.
 
It's highly possible it is a partial agonist so I wouldn't risk i.v.'ing M1 until I see some serious comment on this. At the moment you're like a guinea pig, really.

What relevance does partial agonism have to ROA? I don't understand and I would like to know.
 
So I have a gram of O-Desmethyltramadol coming in the post tomorrow. As someone with no history with opiates (apart from a couple of goes with kratom), what would be the safest way to approach this? Is it the sort of drug you can redose on, or is it very much just dose once and leave alone.

Also to avoid W/Ds, how much time should I leave between use?
 
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