Turing Machine
Bluelighter
- Joined
- Jun 16, 2010
- Messages
- 169
And probably as such, a 5HT2b agonist, which was the reasonm fenfluramine was withdrawn (caused pulmonary hypertension).
Someone else can be the guinea pig for that drug!
Lol, good thing I'm not part of that scene I guess. I'm curious if you feel that 3-fluoroethamphetamine is potentially the most dangerous of the potentially recreational 2,3,4 fluorinated amphetamines with and without N-alkyl groups, because it is the most similar to fenfluramine or if you're equally concerned by the others like 4-FA and 4-FMA or 4-FEA. I'm probably wrong but I was under the impression that in this respect the para-fluoroamphetamines had more potential for risk since at least according to the experience reports they're often used at the high doses necessary to bring entactogenic qualities and these high doses also appear to carry strong appetite suppression as a side effect. The meta and ortho fluorinated amphetamines appear to be used in lower doses and seem to be more strictly stimulants which would imply less general 5-ht affinity, although of course this doesn't say much about 5-ht2b affinity. I suppose the damage from 5-ht2b agonism can take a long time before it is apparent and just because there's no reports of these problems yet with 4-FA doesn't mean that 3-FA and it's N-substituted relatives are not risky even if they are less dangerous than 4-FA.

