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New Drugs in the future???

BTCP and the thiophene-amphetamine-analogues were both reported to be offered by some RC dealers. I do not buy from any of them and can't confirm this though. But the reports are still somewhere here in ADD.

- Murphy
 
i hope somebody finds a few more natural drugs in a rainforest or something. 1 plant could potentialy reveal a whole family of useful chemicals
 
fastandbulbous said:
BTCP has been implicateed in at least one death
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Has it indeed? That is worrying. May I ask for a verification of this info? Where and when did it happen? And is it known where the material was coming from?

Most important, I would be interested how the course of symptoms of the intoxication went.

Thanks! - Murphy
 
It was mentioned in an autopsy (along with MK-801) report of someone who'd obtained a load of it (I think it's linked to via a post on BL). That's all I remember though, but the BTcP bit stuck in my mind as I thought it might be quite a good stimulant, seeing how PCP has a large dopaminergic activity.

Murphy, I'm sure it was you who commented on the hepatotoxicity of 3 substituted benzothiophenes a while back
 
BTPC and dizocilpine?

Sheesh, what a combination, that had to be quite some fucked up experience!
Wonder if it was a conventional drug user of the far out experimenter breed wanting a high, or somebody actually trying to replicate schizophrenia temporarily by combining elements of the dopamine and glutamate hypotheses.
 
Yes, it was me and I still think it's valid. I was not doubting your statement but rather seeked for further insight. Such (hopefully rare) cases of fatalities can provide some insight into how an overdose 'feels' like, in particular in the beginning.
As a (totally unrelated!) example, take the potent hepatotoxins from Amanita phalloides; one really needs to know how the course of an (overdosed) intoxication is going, to decide when its time to seek professional help. I guess when your're already feeling pain in the guts, it's far too late.


Peace! - Murphy
 
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Overdosed? there is no 'right' dose for A.phalloides or its friends and family, not unless you want somebody you really truly dislike to die screaming=D

As for when to seek help, instantly it is even suspected one might have consumed an amatoxic fungus. Well, perhaps shortly after inducing vomiting, preferably shortly before, so the paramedics arrive right after you finish chucking your chips:p

Evil stuff, high mortality rate, and undergoes extensive enterohepatic recirculation, so it gets to arserape your liver sideways, then go back and do it again, and again, and again until you either get on dialysis/plasmapheresis and have the toxins removed or you shit your liver out in a quivering, gelatinous, blood-streaked semilliquified heap.
 
i dont think they prescribe that in the uk for depression, only to help stop smoking. anyway, im sure it wouldnt work.
 
3-fluoroethamphetamine is not that far out and is an analog of fenfluramine, but it has never been mentioned on this site as far as I can tell. IIRC rats and monkeys seem to like it better than ethamp. That said, the only time I ever bought a research chemical from a vendor was methylone. That was probably a good piece of a decade ago. I'm not interested enough to make it myself and I have no real desire to go down the road of buying drugs online again. I'm guessing the UK is the big market for these vendors and it is probably illegal there from the mephedrone hysteria legislation. Ethamphetamine has always interested me, and maybe this is just a reflection of my interest.

There's tons of thiophene versions of existing opioids which could probably make it past analog laws and aren't too potent to be used recreationally. I'm not an expert on this subject but imo as worrisome as research opioids being handled by RC vendors is, the NBOME/NBOH/NBMD psychedelics are much more of a recipe for disaster imo. The parenteral use requirement, the variation in potency from one person to the next, the strong likelihood of mixups between moderate potency compounds and compounds with weapon-like potency levels by vendors who have shown themselves incapable of properly identifying and keeping track of their own stock alongside the language barriers between european vendors and asian synthesis companies and the possibility of contaminants with weapon-like potency in compounds with moderate potency is just asking for a catastrophe.
 
Lazyscience said:
i dont think they prescribe that in the uk for depression, only to help stop smoking. anyway, im sure it wouldnt work.
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Its worth a try. It generally works when the others don't - and it has quite a different method of action to any other AD on the market. It also has little to no discontinuation syndrome, unlike every other AD on the market and it has a much lower side effect profile (other than the effects that come from its relation to phenethylamines such as insomnia, mild increase in blood pressure, weight loss, and appetite suppression when first starting treatment) and especially in the libido department it is favorable to any other AD when it comes to that.

The smoking cessation drug is the exact same drug... I'd be surprised if they don't have bupropion in generic form in the UK though.
 
Turing Machine said:
3-fluoroethamphetamine is not that far out and is an analog of fenfluramine, but it has never been mentioned on this site as far as I can tell. IIRC rats and monkeys seem to like it better than ethamp. That said, the only time I ever bought a research chemical from a vendor was methylone. That was probably a good piece of a decade ago. I'm not interested enough to make it myself and I have no real desire to go down the road of buying drugs online again. I'm guessing the UK is the big market for these vendors and it is probably illegal there from the mephedrone hysteria legislation. Ethamphetamine has always interested me, and maybe this is just a reflection of my interest.

There's tons of thiophene versions of existing opioids which could probably make it past analog laws and aren't too potent to be used recreationally. I'm not an expert on this subject but imo as worrisome as research opioids being handled by RC vendors is, the NBOME/NBOH/NBMD psychedelics are much more of a recipe for disaster imo. The parenteral use requirement, the variation in potency from one person to the next, the strong likelihood of mixups between moderate potency compounds and compounds with weapon-like potency levels by vendors who have shown themselves incapable of properly identifying and keeping track of their own stock alongside the language barriers between european vendors and asian synthesis companies and the possibility of contaminants with weapon-like potency in compounds with moderate potency is just asking for a catastrophe.
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I think any research chemical that is being distributed in the "grey" market is just asking for a catastrophe... Look at AMT and 5-MeO-AMT. How vendors mixed the two up resulting in hospitalizations and at least two known deaths.

I just started reading about the mephedrone disaster - glad I never bought that one - last RC for me was methylone as well.

These greedy vendors really don't give a damn about what they are selling as long as it sells and they make a profit - and the chinese companies doing the synthesizing don't really care to make sure the product is pure either because they're likely not making shit for profit on it.
 
MagickalKat777 said:
Look at AMT and 5-MeO-AMT. How vendors mixed the two up resulting in hospitalizations and at least two known deaths.
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Never understood that. Seems like someone without any chemical knowledge whatsoever could see that 5meo in the full chemical name and tell the difference. I can see how 2c-i/doi could be confused, though obviously there is no excuse for someone selling (or using) these chemicals not to know the difference.
 
Easy to make potent stimulants with high 5-HT activity like meth.

A bit further in the future; electronic drugs, devices that electrically activate receptors. Technology exists.
 
fryingsquirrel said:
Never understood that. Seems like someone without any chemical knowledge whatsoever could see that 5meo in the full chemical name and tell the difference. I can see how 2c-i/doi could be confused, though obviously there is no excuse for someone selling (or using) these chemicals not to know the difference.
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I was one of the victims of the AMT/5-MeO-AMT mishap. Once it was emergency scheduled, I obtained some from a vendor overseas and trusted that it was actually AMT. Took 60mg, my normal AMT dose, and I knew something was wrong when in about 15 minutes later I got super sick, everything started spinning, then the heart palpitations started and my heart rate quickly increased... I was at a house party and I (stupidly) made the decision to drive home - the patterns were more intense than DMT - much more intricate and quite "real" in the sense that they were interactive... Anyway. I ended up calling the ambulance when the chest pains started.

Pulse was 225, BP 190/95. Got to the hospital and told them what I took, they looked it up online, I heard some discussion about how its just going to keep stimulating me until my body gives up and they pumped me full of ativan. After four IV Ativan doses, my body calmed down. They released me 6 hours later and I continued to feel the immense body load of 5-MeO-AMT for two more days with transient hallucinations for another 18 hours and auditory hallucinations for about 20 hours. I don't know how I didn't die that night - and neither does the hospital.

I have not touched research chemicals since - other than M1 - and I don't plan to either. I personally think that these companies (both that do the synth and do the selling) are purely in it for the money and really don't give a damn about anything else, including making sure they are getting the right product out, that the product is pure, etc. Thanks but no thanks.
 
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