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Methoxetamine Discussion Thread

my mxe has finally arrived :D :D :D

here goes first line :>

got some nos to compliment it too :D :D :D

will report back when wonkered
 
phoahhhhhhhhhhhhhhhh. was last night epic or what!!!!!

i had about 100mg+- all up with about 3boxes of nos. man i lost all time/reality/time space continuem etc etc. was stuck in a nos loop for ages felt like eternity until a mate of mine came around. i got him to do a point too and then he too was wonkered for eternety hahah.

def top shit! :D The hole's def not as deep as a k one but the duration fucken owns it. i think i did my lines at like 5-6pm yesterday and by midnight i was still fair fucken wonkered :D
 
headdah said:
phoahhhhhhhhhhhhhhhh. was last night epic or what!!!!!

i had about 100mg+- all up with about 3boxes of nos. man i lost all time/reality/time space continuem etc etc. was stuck in a nos loop for ages felt like eternity until a mate of mine came around. i got him to do a point too and then he too was wonkered for eternety hahah.

def top shit! :D The hole's def not as deep as a k one but the duration fucken owns it. i think i did my lines at like 5-6pm yesterday and by midnight i was still fair fucken wonkered :D
Click to expand...

Sounds amazing, cant wait for my shipment comes. Have you tried without NOS? what was that like
 
yes previous times i did it without nos. its just not the same.

as i was a massive k-head and the general tolerance lingers like a bad fart.

so when i did it without nos. it didn't really have that much effect on me at all.

but this time when combined with nos. It felt like k. like very very similar feel to k!

on a plus note. mxe doesn't seem to do my kidney much harm so far (touch wood)

i remember towards the end of my k days, everytime i indulge, i would get epic pain starting from lower back under the ribs and shooting pain up.

but so far, i have yet to experience this. (THANK YOU JEBUZ) haha

:)
 
NOS is my favorite chemical ever. I've comboed it with K and DXM and have enjoyed those combos immensely. So whenever I do get around to trying MXE then it sounds like I should have a couple boxes of NOS on hand to boost the experience...
 
I would like to say first that the OD is not attributable to Methoxetamine. Huge logical flaw and connotative fallacy here. MDAI AND Methoxetamine were the reported chemicals responsible.

However I would like to send in a harm reduction experience from research:
Subject: male, 20's, 175 lbs, past psychoactive experience a pandora's box
Subject though enjoys the low dose(2mg-10 mg IN bumps used) ope/amp feeling of methoxetamine and does primarily such. He is comfortable with these effects and feels no need to push the envelope.
He would vouch for mu Opiod receptor activity based on past experiences with such active compounds.
After dosing through above mentioned method for 12 hours with an estimated total of only 75-100 mg total used, in combination with moderate alcohol consumption for a highly alcohol tolerant individual (7-10 beers over 3-4 hours). The subject as tiredness was now upon him noticed an alarming degree of respiratory depression. As a regular smoker, subject had not noticed such effects from either opiates or severe smoke consumption(whole cig packs, repeated bong rips, etc.).
Though alarming and potentially fatal, the crisis is said to have been averted through imbibing a tall glass of cold coca cola, with further activity planned to escape the clutches of the nod.

scientific Conclusion:
Methoxetamine is active at opiod receptors, as indicated through severe breathing deprivation.
Methoxetamine provides subtle stimulation, as indicated through mild HR increase and inability to sleep for some time after dosing.
---Methoxetamine loses this stimulative effect after some threshold of time occupied with low dose maintenance usage
By Activation of the brains reward pathways and preservation of nearly normal mental , Methoxetamine could be argued to have high potential for addiction.

the subject will report that Methoxetamine has safely been combined with the following:
-alcohol in moderation
-nicotine
-Cannabis, though this has a potentiating effect on euphoria and psychadelic/dissociative
effect
-phenibut
-doxylamine succinate (unisom)
-ibuprofen
-paracetemol
-tiny amouns of d-amphetamine were used with time spaced in between methoxetamine consumption. Safe but subject cannot comment on higher doses of either substance in this combination.
and the best one he said was:
DUBSTEP!
 
Add to that: subject reported his mild opiate tolerance obliterated by use of methoxetamine. with stronger effects felt from 5mg of oxycodone prescribed for recent injury. Subject though did not mix the active periods of these substances.
 
At once stage I was doing 40mg oxy, when that ended around 60mg of MXE and then when that ended 40ng if oxy etc, worked great for me, no cross tolerance.


It made the MXE feel a LOT more opiatey too.
 
Fixed5217 said:
I would like to say first that the OD is not attributable to Methoxetamine. Huge logical flaw and connotative fallacy here. MDAI AND Methoxetamine were the reported chemicals responsible.
Click to expand...

Yeah thats a given, not sure if that was mentioned in this thread already?

After dosing through above mentioned method for 12 hours with an estimated total of only 75-100 mg total used, in combination with moderate alcohol consumption for a highly alcohol tolerant individual (7-10 beers over 3-4 hours). The subject as tiredness was now upon him noticed an alarming degree of respiratory depression. As a regular smoker, subject had not noticed such effects from either opiates or severe smoke consumption(whole cig packs, repeated bong rips, etc.).
Though alarming and potentially fatal, the crisis is said to have been averted through imbibing a tall glass of cold coca cola, with further activity planned to escape the clutches of the nod.

scientific Conclusion:
Methoxetamine is active at opiod receptors, as indicated through severe breathing deprivation.
Methoxetamine provides subtle stimulation, as indicated through mild HR increase and inability to sleep for some time after dosing.
---Methoxetamine loses this stimulative effect after some threshold of time occupied with low dose maintenance usage
By Activation of the brains reward pathways and preservation of nearly normal mental , Methoxetamine could be argued to have high potential for addiction.
Click to expand...

Are you saying you experienced dangerous levels of respiratory depression?

I've mixed MXE with a good handful of things. Alcohol especially, I would of had well above 10 more like 15 or so standard drinks in a session of MXE at similar doses and experienced effectively zero respiratory effects. While it is definitely a CNS depressant this chem seems far safer to use in combination with other depressants than most other downers. Could it be possible these side effects were more mental than physical?


EDIT::

I've not particularity noticed any of the stimulation you speak of, but I have experienced trouble sleeping on it which I don't get from Ketamine. It takes me a couple hours after the main dissociative effects have worn off before I can sleep, assuming I try to let it happen naturally which never happens ;D Not sure where this effect comes from, it doesn't feel like there's any dopamine activity.

This is about the main factor which stops MXE being feindy for me as if it were K I'd have no objection dosing on weeknights because it wears of so quickly and sleep is easy. MXE lasts many hours and prevents me sleeping meaning I generally wont take it when I have things to do the next day, unlike K which is a free for all.
 
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L3inad said:
Yeah thats a given, not sure if that was mentioned in this thread already?



Are you saying you experienced dangerous levels of respiratory depression?

I've mixed MXE with a good handful of things. Alcohol especially, I would of had well above 10 more like 15 or so standard drinks in a session of MXE at similar doses and experienced effectively zero respiratory effects. While it is definitely a CNS depressant this chem seems far safer to use in combination with other depressants than most other downers. Could it be possible these side effects were more mental than physical?
Click to expand...
YES!-->dangerous respiratory depression
NO-->mental!

The difference here might have been that I rode MXE for ~12 hours.

But after getting back to my apartment (last key bump t-45min) and checking e-mail, etc., I noticed that i kept having to forcefully take lungfuls of air to breathe, or that I would not have taken a breath within a minutes time.
So mental, yes in the sense that the combination of chemicals were active in the brain and caused a visceral response!

JWH in high doses (I used 6g's in a month and a half...shit...) also caused breathing depression but never alarm about the magnitude of effect, even during my mild heart attack OD experience.

I tried to fight it initially by paying attention to a movie (Crash), but kept nodding while breathing got worse. I counteracted with body generated adrenaline to get a glass of coke for ~60mg caffeine. I made it through the movie, at which point I was still tired but noticed that my breathing had largely returned to normal. I took a Unisom at 7am and went to sleep.

With regards to stimulatory effects i normally experience, the alcohol severely overwhelmed them. But normally i can't sleep. Most of the people I have let try it note similar effect, even a friend on a potent brownie noted this.
 
^ that sounds scary, you had breathing issues from comboing with Alcohol specifically? Can you please give more detail about the experience so that everyone can stay safe?

I'm glad you are alright <3
 
girlygrrl said:
^ that sounds scary, you had breathing issues from comboing with Alcohol specifically? Can you please give more detail about the experience so that everyone can stay safe?

I'm glad you are alright <3
Click to expand...

what other details would you like?

i've tried to be as crystal clear about this as I realize some BL'ers tend to ignore adverse effects with compounds they want to enjoy...i.e no one has responded to the report of the mild heart attack I experienced on a JWH OD...

People have damn selective hearing

But let me know, I'll try to recall as best as possible...twas such an interesting night
 
Ahhh its actually rather interesting you said that you experienced this after using for a prolonged period of time.

That gives weight to my theory that MXE has a metabolite with opioid activity, and seemingly with a long half life meaning that continued dosing would allow plasma concentrations (and effects) of the metabolite to continue rising over time, despite the MXE having largely worn off.

I'd say its this metabolite that would be responsible for your respiratory issues, as if it were to have a half life for example of ~8 hours where as MXE's would be more like 2 hours this active metabolite would keep building up, potentially with adverse effects (especially when combined with other CNS depressants). I among quite a few others notice a significant afterglow well into the next day which definitely feels like its from opioid activity, likely from the same metabolite.

People should keep this in mind for future dosing, as it looks like benders could be dangerous when dosing other downers during or recently after having an extended session.

Or I could be completely wrong. :)

Annnnd... that seroquel just kicked in. :| To be resumed.......

Thanks heaps for the heads up fixed.

EDIT:: I cant find any pharmacokinetic info for MXE on google, doesn't look like we really know much about what happens to this chem after it gets the party going upstairs. Assuming it undergoes the same treatment as ketamine because of its structural similarities might prove to be risky when binging as hard as we all do on K ;) Anyone with more information would be awesome.
 
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L3inad said:
Ahhh its actually rather interesting you said that you experienced this after using for a prolonged period of time.

That gives weight to my theory that MXE has a metabolite with opioid activity, and seemingly with a long half life meaning that continued dosing would allow plasma concentrations (and effects) of the metabolite to continue rising over time, despite the MXE having largely worn off.

I'd say its this metabolite that would be responsible for your respiratory issues, as if it were to have a half life for example of ~8 hours where as MXE's would be more like 2 hours this active metabolite would keep building up, potentially with adverse effects (especially when combined with other CNS depressants). I among quite a few others notice a significant afterglow well into the next day which definitely feels like its from opioid activity, likely from the same metabolite.

People should keep this in mind for future dosing, as it looks like benders could be dangerous when dosing other downers during or recently after having an extended session.

Or I could be completely wrong. :)

Annnnd... that seroquel just kicked in. :| To be resumed.......

Thanks heaps for the heads up fixed.

EDIT:: I cant find any pharmacokinetic info for MXE on google, doesn't look like we really know much about what happens to this chem after it gets the party going upstairs. Assuming it undergoes the same treatment as ketamine because of its structural similarities might prove to be risky when binging as hard as we all do on K ;) Anyone with more information would be awesome.
Click to expand...

interesting theory bro, i like!!
 
Off-Topic somewhat...

JWH OD solution -> switch to real pot? JWH doesn't seem worth it, much more dangerous than the real thing.
 
girlygrrl said:
Off-Topic somewhat...

JWH OD solution -> switch to real pot? JWH doesn't seem worth it, much more dangerous than the real thing.
Click to expand...

Some of the newer JWH's have really good highs... definitely on par with prime bud.

anyway I got to try mxe yesterday... it was really nice seemed like it would be great for dubstep club nights.

my first dose was 25mg, then a 2nd another 25mg about 2 hours later

Ive never had ketamine before but from what ive heard and seen I thought the mxe would knock me on my bum, but it wasnt trippy or debilitating at all, I was only a little wonky like i had been drinking. I was clear headed the whole time and the body buzz + music appreciation felt really nice.

I also had a few drinks + tokes of a joint(don't normally smoke anymore), didnt notice any adverse effects... still felt the body buzz a lil bit when i woke up in the morning, slept like a baby.
 
Ketamine has a beautiful next day after glow, does MXE have a similar after glow?
 
i might be missing something but how is everyone shipping mxe from overseas if it is illegal by our analogues act, or hasn't customs caught on or smthing? 8)
 
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