Phenethylamines [Mescaline Subthread] Synthetic / Pure Mescaline - Dosage & Methods of Administration

[Ismene2]

Digging up this old thread to ask if anyone else has tried plugging Mescaline? I'm looking to try mescaline for the first time soon but I've seen mixed responses on how much plugging increases potency. Some have said 200mg is enough plugged, and others saying it doesn't make a big difference.

I'd prefer to plug it to reduce nausea and body load, and it's the way I normally take 2C-B.

Yeah, whenever I ate cactus I was puking up pigs in a blanket like a sick fucking dog so I got a red rubber enema hose, laid on my back with my legs in the air, yelled GERONIMO!! and inserted about half a pint of cactus tea up my rabbits nostril. (Make sure you have a towel beneath you in case of anal leakage).

Trouts notes said you need to hold it up there 30-45 minutes but its so uncomfortable I managed about 20 minutes groaning in pain before dashing to the toilet and pebble dashing the bowl. It does completely eliminate all nausea BUT wasnt very powerful. I tried it a few times but could never hold it much longer than that.

Pure mescaline has been around this year and I never found it very nauseating at all but I wasnt very keen on high dose pure mescaline - its just not psychedelic enough. So what I ended up doing was eating an 00 capsule of mesc, then a couple of blotters of DS 3.0 acid - that is absolutely incredible. Physically, mentally and spiritually the best trip of my life. The synergy between the two is absolutely stunning. I climbed a local peak and stood looking over the forest in the gentle rain and just laughed and laughed.

I still have the red rubber enema hose framed on the wall.

 

[Bicycle Tripper]

Someone designed a cocoa butter method for that, she posted it on the mescaline reddit group.

Is this for synthetic mescaline? I'm confident I can get get the mescaline into solution and squirt it up there, but I'm wondering about dosage and the effect rectal administration/boofing will have on potency (if any).

She tried the ALDHI method (described below) and found it worked very well.

Thanks for this, I'll have a think about foods I eat beforehand.

I still have the red rubber enema hose framed on the wall.

Definitely a story and keepsake you can pass down to the grandkids.

 

[MedicinalUser247]

1000mg. Is a high dose, but any dose above 800mg. gets you sick to your stomach.

 

[Bicycle Tripper]

1000mg. Is a high dose, but any dose above 800mg. gets you sick to your stomach.

That would be a bit much for me, I'm looking for something along the lines of 200ug of LSD, I know it is comparing apples and oranges but not too intense is my aim.

My best guess is to try boofing 300mg at the moment.

 

[Allylbenzene]

Is this for synthetic mescaline?

It applies to both.

Thanks for this, I'll have a think about foods I eat beforehand.

[According to the heterodox explanation] Whilst broccoli (sulforaphane) and vegetable/fish oils (oxidation by-products) will tend to hinder mescaline activity, it's equally important to proactively use aldehyde dehydrogenase inhibitors. That way it should be possible to achieve a strong experience from 50-200mg.

 

[Didgital]

Iv

That would be a bit much for me, I'm looking for something along the lines of 200ug of LSD, I know it is comparing apples and oranges but not too intense is my aim.

My best guess is to try boofing 300mg at the moment.

Ive heard* that boofing doesnt do much* to increase intensity, unlike a lot of other PEAs

 

[xdrc]

Heard the same but no personal experience.

 

[Didgital]

Heard the same but no personal experience.

Kind of odd tbh, pretty much every PEA i can think of seems to increase potency with that ROA. Maybe mesc just that impotent to begin with? Or maybe it is a metabolite that is more active?

Curious

 

[Bicycle Tripper]

Ive heard* that boofing doesnt do much* to increase intensity, unlike a lot of other PEAs

Thanks, I'm okay with no increase in potency, but avoiding nausea would be great and avoiding an overly intense but short experience would be good too.

 

[Didgital]

Thanks, I'm okay with no increase in potency, but avoiding nausea would be great and avoiding an overly intense but short experience would be good too.

Sure. Do you have much experience with mescaline? I find it not very nauseating but I seem to be a little more tolerant to it than most. If you do notice any difference between boof and oral please let us know.

 

[Bicycle Tripper]

It applies to both.

So what do I do with the cocoa butter? Is it to lube up the balloon knot so I can get a syringe up there comfortably?

Sure. Do you have much experience with mescaline? I find it not very nauseating but I seem to be a little more tolerant to it than most. If you do notice any difference between boof and oral please let us know.

I have zero experience with mescaline and like many others have 1g of expensive material that I want to make the most of. I'm happy with 2C-B at ~25mg, ~LSD at 250ug and I've heard mescaline is quite forgiving but I don't want to inadvertently double the potency when I plug it. Sounds like that's not going to happen though. I will report back!

 

[scientificMETHood]

Kind of odd tbh, pretty much every PEA i can think of seems to increase potency with that ROA. Maybe mesc just that impotent to begin with? Or maybe it is a metabolite that is more active?

Curious

You don't put the drugs in your colon to consume them. That's where you take them. From place to place.

You put drugs in the Columns of Uranus. Also known as the anal pillars which are solely in the first inch inside the hole.

The Columns have a lot of superficial blood vessels. If you put the drugs there, then they hit your blood as fast as snorting. That means more drug in your bloodstream sooner which means more availability and means faster comeup, more intense effect and shorter duration.

If you go too deep and put the boof in your colon, which many people often do because they're ignorant, then the come up is more regular.

It's a lot of powder and you should dissolve it in as little water as possible before syringing it into the chute. If mescaline has a reputation for being less potent in the butt, it's probably because people mess up the depth or how much water they use since it's a relatively large amount of powder.

Done right, boofing is second only to IV. Although it requires paraphernalia and butt games the drug experiences are far clearer and more intense, even roa dose adjusted.

 

[Didgital]

You don't put the drugs in your colon to consume them. That's where you take them. From place to place.

You put drugs in the Columns of Uranus. Also known as the anal pillars which are solely in the first inch inside the hole.

The Columns have a lot of superficial blood vessels. If you put the drugs there, then they hit your blood as fast as snorting. That means more drug in your bloodstream sooner which means more availability and means faster comeup, more intense effect and shorter duration.

If you go too deep and put the boof in your colon, which many people often do because they're ignorant, then the come up is more regular.

It's a lot of powder and you should dissolve it in as little water as possible before syringing it into the chute. If mescaline has a reputation for being less potent in the butt, it's probably because people mess up the depth or how much water they use since it's a relatively large amount of powder.

Done right, boofing is second only to IV. Although it requires paraphernalia and butt games the drug experiences are far clearer and more intense, even roa dose adjusted.

I have definitely boofed my friend. I just find it curious that mescaline which is a phenethylamine, is not really more potent when put up the bum. 2C-B, MDMA, MDA, which are also phenethylamines, only 1/3 of a regular oral dose is required to achieve the same level of intensity. Generally speaking I don't value substances so highly that I feel such a need to conserve the remaining doses that I have (maybe 2C-T2 actually) that I will boof.

If I was stranded on a desert island with only a syringe, a bottle of water, and a single gram of 2C-B, I would probably boof a lot more.

I do think the effects are a little bit different, but I seem to tolerate body loads from orally consuming drugs quite well. 2C-E on the other hand, a minimized body load seems very desirable.

 

[G_Chem]

Iv
Ive heard* that boofing doesnt do much* to increase intensity, unlike a lot of other PEAs

Yup that’s my experience too, it’s my belief mescaline needs to be metabolized in some way for proper effects. I’ve noticed some wildly different effects from similar doses amongst people too that leads me to believe it’s due to varying enzymatic activity.

-GC

 

[Allylbenzene]

Yup that’s my experience too, it’s my belief mescaline needs to be metabolized in some way for proper effects. I’ve noticed some wildly different effects from similar doses amongst people too that leads me to believe it’s due to varying enzymatic activity.

This is my conclusion also.
Enzymes in question seem to include SSAO and ALDH.

 

[xdrc]

(maybe 2C-T2 actually) that I will boof.

I know that Pfafffed recommends it -- which is where I got the idea from -- but, personally, I did not find 2C-T-2 benefits from boofing. I found the rocketship come-up quite jarring to handle. It's really just 3-5 min and you are thrown into fullblown tripping, ime. No decrease in bodyload either. My body does not seem to agree with boofing too well as ime bodyload from boofing was always higher than oral consumption for the psychedelics I tried.

 

[Didgital]

I know that Pfafffed recommends it -- which is where I got the idea from -- but, personally, I did not find 2C-T-2 benefits from boofing. I found the rocketship come-up quite jarring to handle. It's really just 3-5 min and you are thrown into fullblown tripping, ime. No decrease in bodyload either. My body does not seem to agree with boofing too well as ime bodyload from boofing was always higher than oral consumption for the psychedelics I tried.

Yeah I spose that rapid of a comeup does sound jarring. I don't even like the comeup of snorting 2C-B or 2C-D. Main reason I'd consider boofing a 2C is to conserve material.. I thought the same with mescaline, but from what I've read, boofing mescaline doesn't seem to increase it's potency/mg like other phenethylamines