[MEGA] Synthetic Cannabinoid Discussion - Take 4

[jeremysdemo]

I've suffered convulsions and blackouts where I'd wake up on the floor from smoking larger amounts, these were generally what most people would consider to be 10-30 doses though. AM2201 was the worst for it.

Just a heads up, if you don't like having to sort out tiny doses all the time, many synths dissolve in vegetable oil at 1mg/ml with agitation and heat.

just a little side tip,

many synth noids are heat sensitive, they degrade in potency if not kept under safe temps, AF-PB-22 for example begins degrading over 32 degress Fahrenheit (according to Cayman chemical data sheet).

that is why solvents are used (like Everclear, Acetone, food grade Ether), mixes can be made even below freezing temperatures with no degredation.

the idea is to keep the potency as high as one can per mg until it is lit up or ingested.....%)

 

[gargamel83]

I can only speak about myselv i was smoking 1g of pure 5f-akb48 for over 2 months, and ofcours i had problems sleeping and swetting alot when i stoped but the biggest problem i have now is that i dont even get high from real cannabis anymore only cannabinoids work, a big fucking problem for me sence they made akb illigal in my country

 

[PKPro]

Were not here to give substance recommendations.

 

[dopemegently]

There's no syncan that's gonna give you type of opiate high your after IMHO but a good starting point would maybe be bb-22; it's got a relaxing body high, and a good duration. If you haven't got access to opiates, you could always buy some kratom, I guess, but that's a topic for a different thread.

 

[dopemegently]

just a little side tip,

many synth noids are heat sensitive, they degrade in potency if not kept under safe temps, AF-PB-22 for example begins degrading over 32 degress Fahrenheit (according to Cayman chemical data sheet).

that is why solvents are used (like Everclear, Acetone, food grade Ether), mixes can be made even below freezing temperatures with no degredation.

the idea is to keep the potency as high as one can per mg until it is lit up or ingested.....%)

Great info there mate; I'll be storing mine in a very cool place from now on. I was wondering about the noids after they've been infused into a smoking blend...do the noids impregnate the substrate herb well, or is there a chance they can shake loose in transit?

Edit: the herb I'm using is marshmallow leaf btw.

 

[ComfortablyNumb95]

^^^
wel, I've had blends staying in a bag for weeks without losing any potency. also, I remember one time when I made a tobacco/5f-akb48 blend but then I somehow lost the bag. I found it days later on my way home (to this day I wonder how the hell it happened), the tobacco was dry as shit and there was some dust inside but it got me high fine so it shouldn't be a problem.

may very well depend on the herb you use for your blend tho.

 

[MDPV_Psychosis]

I think I recently had a seizure from vaporizing too much 5fpb22.

I vaped a tiny amount off foil to test the waters but apparently my dose was way too high. The come up was sudden and shockingly frightening. I just kept getting higher and higher until all of a sudden my mind was stuck in the smallest time loop possible. Time seemed to stop completely. This was the last thing I remember.

I'm not sure how long this went on for but several hours later I woke up completely on the other side of the room. I had a huge bruise around my right armpit. And I could tell I had knocked myself out due to a massive headache and a bump on my head.

I was reckless and paid the price. These newer noids are potent stuff!

 

[pharmakos]

1 gram of 5F-PB-22 is probably 500 doses for a cannabinoid lightweight, i'd reckon. eyeballing isn't really a good idea.[/captainobvious]

 

[dopemegently]

I had a seriously intense experience with pb-22-I found it to be the strongest noid I've vaped pure.i did around 5 mg, and it was too much for me; I couldn't walk or talk, I just crashed out hard for a good 3 hours.

 

[jeremysdemo]

I can only speak about myselv i was smoking 1g of pure 5f-akb48 for over 2 months, and ofcours i had problems sleeping and swetting alot when i stoped but the biggest problem i have now is that i dont even get high from real cannabis anymore only cannabinoids work, a big fucking problem for me sence they made akb illigal in my country

that is crazy. (the amount you were smoking)

It always astounds me how many people I find out were vaping this stuff and lived.

anywho, in a month or so your receptors will slowly reset and MJ should produce it's normal effect....of course that is provided you have not blown out some serious hardware.

 

[jeremysdemo]

^^^
wel, I've had blends staying in a bag for weeks without losing any potency. also, I remember one time when I made a tobacco/5f-akb48 blend but then I somehow lost the bag. I found it days later on my way home (to this day I wonder how the hell it happened), the tobacco was dry as shit and there was some dust inside but it got me high fine so it shouldn't be a problem.

may very well depend on the herb you use for your blend tho.

my post was a response to someone who was "heating" oil to dissolve their noids.

in room temperate the degredation is happening....but at a very slow rate depending on the noid, some store fine at room temperature, others require lower temperatures to last a year or two.

all of that data is usually available on their safety data sheets....what am I saying! like people are actually concerned with safety that are vaping noids! lol

 

[ComfortablyNumb95]

I was answering this

I was wondering about the noids after they've been infused into a smoking blend...do the noids impregnate the substrate herb well, or is there a chance they can shake loose in transit?

but anyways useful information thanks for the input

 

[jeremysdemo]

10-4, and sorry about that, this happens sometimes before my second cup of tea,

to answer gentlys question myself, they do permeate the substrate and do not shake loose in transit,

I have seen stuff tho that does not, like crystals, when the substrate is already saturated with as much as it could absorb.

the commercial blends I have seen have a lot of unabsorbed crystals not only on the outside of the leaves but at the bottom of the bag.

that stuff is just crazy, giving users no idea whatsover how much they are dosing.

it's a shame really, noids were out for almost a decade of responsible research before the media and government let all the kidies know about it and blew it up in the media, then the hospital reports of OD's got greater and greater until their "crisis" was a reality!

 

[naddybounce]

^^ Anyone can correct me if I'm wrong, but I'm pretty sure non of them last long. I honestly get a ten minute MAYBE 15 minutes high from these things, they're like the crack of the weed world

I couldn't have said it better myself

 

[naddybounce]

that is crazy. (the amount you were smoking)

It always astounds me how many people I find out were vaping this stuff and lived.

anywho, in a month or so your receptors will slowly reset and MJ should produce it's normal effect....of course that is provided you have not blown out some serious hardware.

Can you "blow out" a cannabinoid receptor? I had the same problem, where as it took me a few months before I could smoke regular weed again. Is there actually a chance I may have damaged my receptors to the point that they aren't functioning properly?

 

[pharmakos]

i've heard that switching to cannabis only and smoking it just once in awhile works to get your body to start responding normally to "regular weed"

the problems with desensitization to cannabis only occurs with really heavy syncan smoking, though. weed works fine for me since i cut back my synth smoking.

 

[Felonious Monk]

Wow. I'm glad I got out of blends when I did. I smoked them pretty heavily for a while (in my mind--few joints a day for a period of months), but quit when I felt any positives of smoking were outweighed by the obvious negatives. I developed stomach problems during the time I was smoking them which I'm 99% are unrelated, but the thought dogs me...
Now 2 years since I've smoked any I still have terrible stomach problems. Probably not from smoking blends but I can't say for sure.

They definitely fucked up my cannabinoid receptors, it was weird going back to smoking real weed, starting slow and on/off with blends helped though. Today I get just as high from smoking a bowl as I ever have (possibly higher--after taking a long break and then starting blends before bud my THC tolerance has never reached the same level I believe, despite smoking concentrates and eating edibles everyday now).
So don't worry too much about blowing your receptors. Just give your body time to heal, take time off all cannabinoids for a while if you can.

 

[dopemegently]

Yeah, I've noticed a small but noticeable tolerance to noids after just a couple weeks use. It took a good 2 full-sized joints of my blend to get stoned, and the blend was pretty strong. I put this down to smoking the pure noids in higher doses than I could handle; as I said earlier, I guess these thing really mess with your receptors; I know this first-hand now, I guess. So, I probably will take a certain time off smoking them - I don't want to be smoking insane amounts of noids like some people I've heard.

 

[dopemegently]

10-4, and sorry about that, this happens sometimes before my second cup of tea,

to answer gentlys question myself, they do permeate the substrate and do not shake loose in transit,

I have seen stuff tho that does not, like crystals, when the substrate is already saturated with as much as it could absorb.

the commercial blends I have seen have a lot of unabsorbed crystals not only on the outside of the leaves but at the bottom of the bag.

that stuff is just crazy, giving users no idea whatsover how much they are dosing.

it's a shame really, noids were out for almost a decade of responsible research before the media and government let all the kidies know about it and blew it up in the media, then the hospital reports of OD's got greater and greater until their "crisis" was a reality!

It gets me furious tbh how reckless and short-sighted these headshops/ commercial blend manufacturers have been; it's like they've purposely set out to destroy a perfectly viable product, by making unsafe shit that can fuck people up, which of course is gonna make it to the media, which of course is gonna demonise the product, making a ban a certainty. If you type in "spice" now, the only results are headshops selling blends, and hundreds of media scare stories warning everybody that syncan blends are poison. It's a shame, is all.

Anyway, maybe seeing the crystals on the surface of the blend is a result of the inefficient way they infuse their substrate with noids; they all spray it, as far as I know. Maybe spraying the surface of the substrate causes it to fail to impregnate the herb properly, coating only the surface? From what I've read by other posters, this method creates hotspots of pure Syncans, and that's exactly what I blame when I hear people having seriously bad reactions to the commercial blends. As I know, smoking too much of a pure noid can really fuck you up in a bad way.

Edit: If I store my blend in airtight containers in my fridge, would this help avoid the slow degradation I've been hearing about?

 

[jeremysdemo]

Can you "blow out" a cannabinoid receptor? I had the same problem, where as it took me a few months before I could smoke regular weed again. Is there actually a chance I may have damaged my receptors to the point that they aren't functioning properly?

sorry if you took my jab seriously.

when pot came out that had 18-25% THC and little to no CBD the same thing was happening to people, they called it burn out.

tolerance tends to build up over time, one might get high off low grade homegrown at first, but chasing the dragon they slowly go for higher and higher till homegrown does virtually nothing and they call it crap, actually it is still the same homegrown it always was!

obviously the curve for synth noids is much higher, someone could theoretically raise their CB receptor threshold level on the first toke if the stuff is strong enough!

there are a lot of dangers involved in noids not found in MJ because of the many ways in which they can be combined with seemingly inert molecules of other substances (this became more prevalent when companies tried to skirt the laws). the body has to process these molecules in various ways, some of them metabolize into dangerous substances for the body, eg. even fluoropentyl-indoles chains into fluorotoxicity (which builds up in the hypothalamus) napthelene chains which are cancerous along with overdose related damage to liver and kidneys.

the endocannabiniod system of the body regulates many things from the nervous system to the immune system, so extreme amounts of anything that will deregulate it one way or another has the potential to cause damage.

there are actually reverse agonist for most synthetic cannabinoids, so it is always wise to know your cannabinoid in the event of acute overdoes, it could save your life, your organs, etc.

I always tell people, don't be afraid of "getting caught" from smoking noids if you are already at the ER, they are going to find out one way or the other when your results fly off the chart, just let them know what you took so they can give you the antidote if they have it!

I hope what I said above answers your question, you could burn out something (like your hypothalamus) with toxic fluoride or an organ, so do your research, BEFORE you do your research if ya know what I mean.....
I think your receptors will always bounce back in time, one might even go as far as believing that is what God gave them to us for! OR that is why we evolved into needing them....which ever way one likes to look at it. %)