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[MEGA]Synthetic Cannabinoid Discussion- 2nd Toke

When I feel anxious after smoking, which is quite rare, i lay on my back and it really helps me relax too. I usually listen to trance music and close my eyes, and then I just think about something positive and I try to focus on these positive thoughts. I personally don't think anxiety has something to do with blood pressure, but I've never heard anything about that so I might be wrong. Laying on your back/listening to music/closing your eyes simply relaxes you regardless if you are high or not, so it's logical that it reduces anxiety.

Also, if you experience anxiety each time you smoke, try smoking smaller amounts or try smoking a different strain.
 
revelator said:
i think the one more people should try is jwh 210 its strong active like 18 i think it is a analouge of 250 although someone will have to correct me on this. it is highly euphoric heady and lasts like 3+ hours. a great legal one for the time being. imo
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Um, I do believe it's non-analogous to any of the common JWHs. It's the only cannabinoid that I've found (Though I've only looked at like 20)that bypasses the proposed synthetic drug control law, because it's ethylnaphthalyn/pentylindol(I'm really stupid when it comes to chemicals, I don't know which part is actually labeled in th SDCA, planning on taking a chemistry class though!) and that's the only one I've found not listed in the SDCA. So even them trying to ban everything fails.
 
I've been trying to find the best dose and ROA of JWH-081 for me. I've worked my way up to 50mg, both orally in cream and smoked (cigarette tip, pipe). Orally, I felt no effects, and smoking 2-3 hits makes me feel more drugged than stoned. Nothing close to a cannabis experience. Plus, it seems so toxic when smoked because it honestly tastes like you're smoking plastic. I haven't giiven up and plan to buy some 210 for comparison. Has this happened to anyone else?
 
I am also curious of this. It seems like am 2201 is one of the most widely available. Does this one have tentancy for panic? I was read up on the thread and postings, but I figure there's probably no one bertter than the cannibus discussion mod to ask.
 
IME AM-2201 is much less anxiogenic than JWH-018. The latter gave me the fear like nothing else ever has, and I didn't have high hopes for the former given the structural similarity, but was very pleasantly surprised. It's a very nice high. Chainer's a badboy who doesn't get anxiety from anything so I can't imagine he'll have much to say on the issue.
 
Well seeing that he was helpful with my other questions that he would still know popular opionion in "the fear" whether he gets it or not. But thanks Vader/ You got any suggestions for a newbie at herbal blending? I'm a low level spert when it comes to RC stimulants but not much knowledge of cannabinoids.
I see 122 would be quite easy to obtain for me right now. Suggestions to look for something else? I know they are all likely illegal due to analog laws, but I'd much rather not get a jwh that was listed back in march.
 
JWH-122 has often been reported as peoples' second or third favorite cannabinoid, out of 6-10. I haven't personally tried it but IIRC it can last up to 5 hours, which is great! But as far as anxiety it's kinda in the middle, not like 018 where it's near impossible to avoid anxiety, but definitely not 250 either where anxiety is almost non-existent. It's great if you've had experience with other cannabinoids very often, but if you're going to use it for a first time, a 5 hour trip disaster isn't fun.

And no they're not illegal due to analog laws, JWH-210 especially, it's not an analog of any of the banned cannabinoids, and it's almost a completely different chemical makeup than any other cannabinoid that is commonly used.

On an unrelated note, people need to stop saying rc cannabinoids are unresearched and possibly dangerous. The reality is they have been researched and have been proven in many cases to have neuroprotective, anti-inflammatory, and analgesic effects. In some cases they have also been shown to have a possible anti-cancerous effect. Though if you're smoking some horse shit mixed with JWH-XXX, god knows what you're inhaling and I'm atheist. If you can make it yourself(I don't know why anyone that's smart enough to wouldn't), which requires a high knowledge of chemistry, then go for it and be happy that you're inhaling a 99.9% pure chemical that has anti-cancerous, anti-inflammatory, and neuroprotective effects.
 
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I took a month long break and stayed completely sober for the whole time after about a year of smoking weed almost daily. When I got back to tokin' it was crazy. A bit of SLH leaf had me thinking of how my water boiler correlates with my life. :D
When I got some bud spillin' through my brain cells it could only be called tripping, and the paranoia was strong as hell too. I figured it was a tolerance issue rather than a problem with myself. Turned out I was right, after about 3 weeks of "tuning my tolerance" I got back to getting some really enjoyable highs.
Even a week without smoking, and then packing a nice bowl has made me stand at the front door wondering if there really IS someone on the other side, repeating the classic lines of "Dude, you're just too high, ok?".
I'm somewhat paranoid by nature, so it explains part of the aforementioned, and present company certainly had a clear effect.
So I dare claim that if paranoia starts peaking after a break, and it's not completely intolerable, then the "deal with it" attitude can be a solution. (Definitely not a medical opinion. :D)

Edit: Oh yeah, and as many tokers probably know already: the strain being smoked should never be underestimated. Get stoned instead of high (Roll those indicas up, Johnson!) and the CIA might not be after you after all.
 
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hmm, i don't mean to be an ass but i gotta respond to that last comment :)

Cannabinoids IN GENERAL are safe-- look at the years of research that has been done on weed -- but RC cannabinoids have been reported to have an increased incidence of anxiety and panic attacks. Perhaps this is simply because people are overdoing the dose. But when there are a few cases of people getting MAJOR full-body system imbalances that look like parkinson's or severe depression, some consideration MUST be made into the fact that these RC cannabinoids are still BRAND NEW drugs. Every Body reacts differently, and chemically speaking many of the RC cannabinoids are completely unrelated structurally to THC itself. This means that perhaps most people have bodies that simply respond to JWH-018 like they respond to THC. But there are those select few who may have an allergic reaction, or completely intolerant immune system or liver that cannot break down the active products.

There are cases of people who have never had a hit of marijuana in their lives, rolling up a gigantic cigar of Spice. That kind of full-scale fuckery with the body's cannabinoid system (as you have said, is implicated in neuroprotective, anti-inflammatory, and analgesic responsibilities) can certainly knock someone's well-being out of whack for a long time.

Just because SOME people can take a blunt to the face and function normally doesn't mean that EVERY person can. And the synthetics are up to 100x potency of pure THC. So treat them with respect and be safe.
 
^ You should research many of the common JWHs and WIN 55,212-2, that has treated some effects of Alzheimer's iirc. Some inflammation of some neurotransmitter in the brain. http://www.ncbi.nlm.nih.gov/pubmed/20667450 you can argue with the federal government if you want. Though I guess to read that article you need to be somewhat of an insanely experienced doctor.
Here's my interpretation of it if you'd like to read it.
It keeps your brain from dying and is good for you.
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And you know WHY synthetic cannabinoids cause anxiety? Because they're full agonists, not partial. They're up to 200x more potent than THC and people generally start at a mg or two, which is like trip-disaster-level for some of the more potent cannabinoids.

As for the mental disorders, those are mental disorders. You take a drug with an underlying mental disorder and it gets exacerbated and becomes no-longer-underlying.
Some more articles to calm you:
http://www.jneurosci.org/content/29/14/4564.full.pdf JWH-015 is neuroprotective.
http://www.fasebj.org/content/24/3/788.full JWH-133 is neuroprotective.
http://www.ncbi.nlm.nih.gov/pubmed/15728830 (sorry if we're not supposed to reference opposing forums but this is important) JWH-133 a possible cure for Alzheimer's.I just substituted the link to the study for the link to the discussion of it on another forum, hope that's OK- Vader

Look, people can have certain forms of seizures from drinking fucking water, so should we label that as dangerously toxic, too?

One more article that covers every single type of CB2 agonist (which 99.999999999% of cannabinoids are at least partially)and states neuroprotectivity and no harmful effects http://www.pdonlineresearch.org/responses/22275/6982/cb2-agonists-neuroprotection-mptp-model

Who knows what's actually making these kids freak out and have a seizure or black out? These cannabinoids are sold impurely to a middle man who sprays them all over god knows what that's been sitting god knows where for god knows how long, and I'm atheist. Then these dumbshit kids smoke something that's active orally at nearly the same dose. You were saying what could be said about anything "may have an allergic reaction" people have an allergic reaction to their own cum, I think it's safe to say no matter what chemical you come up with, it's going to cause allergies in some people.

and I'm done raging for now.

Edit: HU-210 is about 700x more potent than THC

another edit: lol along with a cannabinoid ban, my state made codeine schedule 1. tards. I hope one of these days the government pisses of apple or some company addicted to creating lawsuits and gets fucked.
 
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On an unrelated note, people need to stop saying rc cannabinoids are unresearched and possibly dangerous. The reality is they have been researched and have been proven in many cases to have neuroprotective, anti-inflammatory, and analgesic effects. In some cases they have also been shown to have a possible anti-cancerous effect.
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When people talk about "unresearched cannabinoids", they don't mean that no research whatsoever has been done on them. They mean that large-scale studies of long-term toxicity in humans have not been undertaken, which they have not. We all know that CB agonists have medical utility, but there could well hazards associated with these drugs that have yet to be recognised. As Big Don said, "the absence of evidence is not the evidence of absence".
 
i feel like everyone knows what i'm thinking so i'm too scared to think about stuff.. and i'm afraid that when i'm out in places then EVERYONE knows i'm high.. and i feel like i'm a horrible person for being places where there are kids even though they have no idea.. i still feel like i'm setting a bad example! it doesnt happen very often but sometimes..
 
for me it's the worst when i do a big load on the vape by myself. i get 5-10 minutes worth of irrational fears and anxieties about my life, but it always goes away just as quickly.

knowing that it's going to pass helps a lot with getting through it. likewise, i use it as a signal that it's time to do something (usually work out or do math) to relax and focus on something else.
 
i get paranoid that people are using me and that people think i'm retarded. I almost never pick up my phone because im paranoid about what the caller is going to say - when in reality it's usually just someone hitting me to chill.
 
^ Yeah, but you have to admit with all the people that are using these if something was seriously wrong with them, it would be noticed quickly. There aren't any inorganic substances I can think of that would take longer than a year or two of low-moderate usage to manifest symptoms. Of course maybe if you're in a house with lead paint and you lick the walls once a week, it may take 20 years to do anything. But people are putting grams of this into their bodies every week. In very rare, extreme cases, grams a day. The worst most of these people get is crappy lungs, which is to be expected when you're too stupid to realize a chemical is active orally.
 
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How long have people been using these drugs for, though? 3 years or so? That's not long enough to know that there are no adverse effects caused by persistent use. Look at ketamine- everyone thought that it was a drug with little potential to cause physical damage. However, as use becomes more widespread, eventually it becomes obvious that long-term heavy use causes serious bladder damage. Ketamine had been an approved medicine for years, gone through clinical trials, seen huge amounts of research, and still it took time for the danger to be realised. The synthetic cannabinoids have nothing like that kind of track record, and no-one should assume that there are no adverse effects from heavy daily use.

As for calling people who smoke these drugs stupid, it's rude and it's wearing thin. On top of which, it's silly. Cannabis is orally active, but most people on this board smoke it, for the same reasons that they choose to smoke JWHs- the high is gentler, shorter lasting, and more predictable, and the dose easier to titrate.
 
Vader said:
Chainer's a badboy who doesn't get anxiety from anything so I can't imagine he'll have much to say on the issue.
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Lol now I get the feeling you're mocking me. I'm not sure drugs not bringing about a particular side effect would qualify me as a bad boy, either. I can start lying and say it causes anxiety if that make's everyone happier, though.
 
Chainer said:
Lol now I get the feeling you're mocking me. I'm not sure drugs not bringing about a particular side effect would qualify me as a bad boy, either. I can start lying and say it causes anxiety if that make's everyone happier, though.
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It wouldn't make me happy but it sure as hell would make you seem less likely to be a robot. I don't see how anyone could not get a little antsy after smoking too much 018.

I think he meant to say bad ass not bad boy.


btw, suppost to get 2 grams 122 in soon. What would you suggest to do with it? I still have 1 pound of mullien and damiana minus half an ounce.

btw- I was a smoker of about 8 years before I got a job that requires regular randoms. That's kind of how I got into RC's to begin with. just figured I'd let yall in on that info so you wouldn't think I'm just some RC crazied maniac making crazy creations.
 
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