Low doses of psychedelics for extra energy and as a motivational boost

[mission780]

Low dose LSD is a great anti-depressant/motivator/energizer.

What's a low dose? Hard to gauge with pre-fabbed blotters from who knows where but generally equivalent of 50-70 mics seems to do the trick. Great night at the bar or any other social place.

Just my 2 cents...

I'd say even half of it (25-35mics) is enough.

 

[EarthBounded]

IMO this is a terrible idea, I did it for years and it made me delusional at one point

 

[mission780]

IMO this is a terrible idea, I did it for years and it made me delusional at one point

What drug are you referring to? LSD?

How often and how much have you taken?

 

[Viṣakaṇṭha]

I did this pretty steadily for about a year or so around 5-6 years back. I used to take small hits of acid and go about my work day just fine (and at the time I was working with highly expensive and complicated film equipment and had no real difficulties). Mescaline is certainly a nice stimulating substance, but some of the somatic effects (and the time it takes for me to prepare) make it less pragmatic than acid. In fact, I loved lsd as a stimulant so much that I probably wouldve continued using it if I hadn't found out that strychnine is also a stimulant, and its effects are extremely similar to a non-hallucinogenic dose of acid. And with strychnine, since I extract it myself, I know exactly what Im getting (as far as product and dosage is concerned), its infinitely cheaper, and I have constant/unlimited access due to not having to rely on dealers

 

[mission780]

I did this pretty steadily for about a year or so around 5-6 years back. I used to take small hits of acid and go about my work day just fine (and at the time I was working with highly expensive and complicated film equipment and had no real difficulties). Mescaline is certainly a nice stimulating substance, but some of the somatic effects (and the time it takes for me to prepare) make it less pragmatic than acid. In fact, I loved lsd as a stimulant so much that I probably wouldve continued using it if I hadn't found out that strychnine is also a stimulant, and its effects are extremely similar to a non-hallucinogenic dose of acid. And with strychnine, since I extract it myself, I know exactly what Im getting (as far as product and dosage is concerned), its infinitely cheaper, and I have constant/unlimited access due to not having to rely on dealers

Strychnine is very toxic to humans and LSD is not. For this sole reason I would choose LSD despite the price and tolerance problem.
Besides for me LSD effects are not only about stimulation, they are mainly about cognitive enhancement, e.g. making more associations, having wider perspective on things, greater creativity.

 

[Viṣakaṇṭha]

Oh certainly...yeah, toxicity is definitely an issue, which is why it should only be used by people who are 100% positive in their abilities at extraction. I definitely wouldn't recommend it to the average joe. Although it is unfortunate it has to be that way, because in countries where strychnine doesn't have the stigma attached to it that it does here, nux-vomica preparations are still in use

Its interesting that you brought up the issue of cognitive enhancement, if you do a google search on strychnine and nootropic, you'll notice that this substance is also known for it's cognitive enhancing abilities as well.

Also, Strychnine (in the correct doses, of course) has had a wide variety of other health benefits attributed to it throughout history that lsd has not. I really do love them both, but strychnine has just become much more of a practical everyday substance for myself...it has infinite amounts of uses, shorter duration, a greater availability, and the knowledge that I know exactly what Im ingesting makes it more intriguing for me...particularly on the issue of extra energy and motivational boost.

 

[mission780]

Oh certainly...yeah, toxicity is definitely an issue, which is why it should only be used by people who are 100% positive in their abilities at extraction. I definitely wouldn't recommend it to the average joe. Although it is unfortunate it has to be that way, because in countries where strychnine doesn't have the stigma attached to it that it does here, nux-vomica preparations are still in use

Its interesting that you brought up the issue of cognitive enhancement, if you do a google search on strychnine and nootropic, you'll notice that this substance is also known for it's cognitive enhancing abilities as well.

Also, Strychnine (in the correct doses, of course) has had a wide variety of other health benefits attributed to it throughout history that lsd has not. I really do love them both, but strychnine has just become much more of a practical everyday substance for myself...it has infinite amounts of uses, shorter duration, a greater availability, and the knowledge that I know exactly what Im ingesting makes it more intriguing for me...particularly on the issue of extra energy and motivational boost.

Thanks for the extra information. It sounds really good - strychnine as a substance that can be used everyday as a stimulant and nootropic - WOW! But I still don't get the toxicity thing. I have no knowledge of chemistry, so I would like to ask very plainly - do you mean that it is possible to extract strychnine in a way that it isn't toxic any more? How to know if the stuff sold in the market is toxic or not?

 

[Viṣakaṇṭha]

Thanks for the extra information. It sounds really good - strychnine as a substance that can be used everyday as a stimulant and nootropic - WOW! But I still don't get the toxicity thing. I have no knowledge of chemistry, so I would like to ask very plainly - do you mean that it is possible to extract strychnine in a way that it isn't toxic any more?

Yep, not a problem at all! Yeah, the history of the chemical is really fascinating! It was even used as a performance enhancing substance at times...there's several famous instances of olympic athletes partaking in strychnine use.

As far as extracting it in a way that's not toxic the answer would objectively be yes...This is primarily because strychnine's toxicity (like all issues of toxicity) is essentially based upon the dosage used. Paracelsus is often described as the founder of toxicology, and he has a rather infamous statement that reads, "All things are poison, and nothing is without poison; only the dose permits something not to be poisonous." And that's pretty much exactly the case with strychnine. It can most definiely be extracted to small quantities where it is no longer toxic to ingest. And it was used historically in such a manner for quite a while. In fact, while there is no doubt that it is a powerdul substance....its toxicity level is quite the same as that of nicotine's (LD50 of 1–2 mg/kg in humans for strychnine, and an LD50 of 0.5–1.0 mg/kg for nicotine).

How to know if the stuff sold in the market is toxic or not?

But yeah, herein lies the problem :D Some countries will still offer Nux-Vomica tinctures (Nux-vomica is the seed from which strychnine is extracted), lol but we're unfortunately not one of them. And this is the main safety issue with the substance...since there are no professional pharmaceutical grade tinctures of the substance, it forces those who might potentially be interested to consider doing an extraction themselves, which is HIGHLY dangerous.

Although all that is quite a shame. I've gotten proficient at the extraction and I really do find it to be somewhat of a wonder drug. Its my favorite stimulant (which is fascinating bc im not even really a huge fan of stimulants to begin with), it's my favorite nootropic, and it works wonders as far as the potentiation of psychedelics. But unfortunately, since this is a harm reduction site, I can't really say I recommend it bc the extraction process is definitely extremely dangerous...but I do hope that one day our society will develop a more open and objective view towards these substances, because if used in the correct manner and with the correct dosage they offer infinite amounts of potential.

 

[mission780]

Yep, not a problem at all! Yeah, the history of the chemical is really fascinating! It was even used as a performance enhancing substance at times...there's several famous instances of olympic athletes partaking in strychnine use.

As far as extracting it in a way that's not toxic the answer would objectively be yes...This is primarily because strychnine's toxicity (like all issues of toxicity) is essentially based upon the dosage used. Paracelsus is often described as the founder of toxicology, and he has a rather infamous statement that reads, "All things are poison, and nothing is without poison; only the dose permits something not to be poisonous." And that's pretty much exactly the case with strychnine. It can most definiely be extracted to small quantities where it is no longer toxic to ingest. And it was used historically in such a manner for quite a while. In fact, while there is no doubt that it is a powerdul substance....its toxicity level is quite the same as that of nicotine's (LD50 of 1–2 mg/kg in humans for strychnine, and an LD50 of 0.5–1.0 mg/kg for nicotine).



But yeah, herein lies the problem :D Some countries will still offer Nux-Vomica tinctures (Nux-vomica is the seed from which strychnine is extracted), lol but we're unfortunately not one of them. And this is the main safety issue with the substance...since there are no professional pharmaceutical grade tinctures of the substance, it forces those who might potentially be interested to consider doing an extraction themselves, which is HIGHLY dangerous.

Although all that is quite a shame. I've gotten proficient at the extraction and I really do find it to be somewhat of a wonder drug. Its my favorite stimulant (which is fascinating bc im not even really a huge fan of stimulants to begin with), it's my favorite nootropic, and it works wonders as far as the potentiation of psychedelics. But unfortunately, since this is a harm reduction site, I can't really say I recommend it bc the extraction process is definitely extremely dangerous...but I do hope that one day our society will develop a more open and objective view towards these substances, because if used in the correct manner and with the correct dosage they offer infinite amounts of potential.

Interesting!

So if I understand correctly it's all about the precise dose - not overdosing this substance. In case one is able to get pharmaceutical grade strychnine and is very careful about the proper dose - the substance doesn't cause big risks?

What are the side effects of using strychnine in low non-toxic doses? Have you ever experience any?

Can strychnine be taken without harm if one also uses psychedelic drugs (like LSD, 2c-family) or nootropics (racetams, choline, selegiline)? Or should it be taken only on its own?

 

[mission780]

Can anybody please advise me regarding cutting/dividing LSD blotters in order to get a lower dose that is quite precise.

Are LSD blotters covers with acid evenly on the whole surface? For example, if I had a 100mcgs blotter and split it into two exact halfs,
can I be sure each one of them will be 50mcgs. And a quarter of blotter will be 25mcgs?

I don't know the technique of producing blotters. I've always assumed the (blotter) sheet is being soaks in liquid LSD. If it is so,
the acid should be evenly spreaded on each blotter and the technique of cutting blotter into smaller pieces should prove precise enough
to get the right amounts of low doses. Or am I making a mistake somewhere?

Or there is a better way of getting precise low doses from LSD blotter? Would dissolving LSD blotter in (refrigerated distilled) water work better?

 

[Psychonautical]

Noopept 3 doses throughout the entire day,
Is like a low dose psychedelic by the time the second dose kicks in.

But you can actually feel it healing your brain.

 

[mission780]

Noopept 3 doses throughout the entire day,
Is like a low dose psychedelic by the time the second dose kicks in.

But you can actually feel it healing your brain.

To what exactly psychedelic do you refer? At what dose?

 

[Psychonautical]

It's called Noopept, it is a Nootropic. other wise known as N-phenylacetyl-L-prolylglycine ethyl ester)
It isn't a Psychedelic. 1000 times more potent than the prototypical racetam drug, piracetam.

Basically what you do it, you take 10-30mg under the tounge 1-3 times a day.


Now i think it's safe to say, on here we all have a little bit of brain damage.
I wanted to purchase some because i don't think any psychedelic is going to be able to repair the few gaps in my memory that i have.
But Honestly. Since taking Noopept, i've noticed that. My Vision, and my attention to details has increased within 1 week of treatment
about 10 fold, in comparison to what it was.

It's weird, literally the drug has no effects outside of feeling like a cup of coffee than enhances you vision and lasts all day long.
In Russia, Noopept is considered a nootropic drug with neuroprotective properties. It is reported to improve learning ability and memory (including the initial processing of information, consolidation, and retrieval). It is also used to prevent the development of amnesia induced by electroshock.

In studies Noopept helped to restore memory and other cognitive functions disturbed as a result of ischemia as well as damage due to hypoxia.[16][17] The therapeutic effect of the drug in patients with organic disorders of the central nervous system appeared within 5-7 days of treatment. Also reported was the reduction or disappearance of anxiety, irritability, emotional lability and sleep disorders.

It has also been observed to reverse and prevent learned helplessness neurosis in rats and primates after long term (21 day) treatment.

Meaning that they took a bunch of maze running rats, and monkeys. Instead of giving them a reward, at the endof their trail.
They would get punished. So after a long enough time of thinking they are going to be rewarded for doing "good work"
They develop a learned Helpless Neurosis, which makes them think that nothing they can do is right.
So, in some experiments both with and without noopept, They would flood the maze, and if the Neurosis was so deep in the monkey, or rat.
They wouldn't run the maze, and they would other wise meet their demise.

Now the animals who had been given the exact same neurosis and put into the same situation,
When given Noopept for 21 days, despite the maze flooding, actually ran it as if it was something enjoyable and rewarding.

I've also noticed that it literally has given me a new way to think about almost everything. Which is quite awesome.
But not like a psychedelic out there, sort of way.

 

[mission780]

It's called Noopept, it is a Nootropic. other wise known as N-phenylacetyl-L-prolylglycine ethyl ester)
It isn't a Psychedelic. 1000 times more potent than the prototypical racetam drug, piracetam.

Basically what you do it, you take 10-30mg under the tounge 1-3 times a day.


Now i think it's safe to say, on here we all have a little bit of brain damage.
I wanted to purchase some because i don't think any psychedelic is going to be able to repair the few gaps in my memory that i have.
But Honestly. Since taking Noopept, i've noticed that. My Vision, and my attention to details has increased within 1 week of treatment
about 10 fold, in comparison to what it was.

It's weird, literally the drug has no effects outside of feeling like a cup of coffee than enhances you vision and lasts all day long.
In Russia, Noopept is considered a nootropic drug with neuroprotective properties. It is reported to improve learning ability and memory (including the initial processing of information, consolidation, and retrieval). It is also used to prevent the development of amnesia induced by electroshock.

In studies Noopept helped to restore memory and other cognitive functions disturbed as a result of ischemia as well as damage due to hypoxia.[16][17] The therapeutic effect of the drug in patients with organic disorders of the central nervous system appeared within 5-7 days of treatment. Also reported was the reduction or disappearance of anxiety, irritability, emotional lability and sleep disorders.

It has also been observed to reverse and prevent learned helplessness neurosis in rats and primates after long term (21 day) treatment.

Meaning that they took a bunch of maze running rats, and monkeys. Instead of giving them a reward, at the endof their trail.
They would get punished. So after a long enough time of thinking they are going to be rewarded for doing "good work"
They develop a learned Helpless Neurosis, which makes them think that nothing they can do is right.
So, in some experiments both with and without noopept, They would flood the maze, and if the Neurosis was so deep in the monkey, or rat.
They wouldn't run the maze, and they would other wise meet their demise.

Now the animals who had been given the exact same neurosis and put into the same situation,
When given Noopept for 21 days, despite the maze flooding, actually ran it as if it was something enjoyable and rewarding.

I've also noticed that it literally has given me a new way to think about almost everything. Which is quite awesome.
But not like a psychedelic out there, sort of way.

I've read about Noopept but never tried it yet. From racetams I've only tried Piracetam at 600-1200mg, but I don't see big effects. From what you wrote about Noopept I suspect it's entirely different thing than Piracetam. I will be happy to try it one day.

Anyway, my approach to low dose psychedelics as nootropics might be a little different. I don't feel I need to heal anything in my brain (although I cannot be sure). My main goal is to get improvement in the following areas: clear reasoning, faster thinking, greater creativity, mood and motivation boost, wide perspective on things, better problem solving skills. And this is what low dose LSD can do for me perfectly!

I wonder if anybody here could compare the effects of Noopept to low dose LSD?

 

[Psychonautical]

I think you could, meaning that if you took like 100mg of noopept throughout the entire day.
By the time you go to bed, i'd imagine the feeling you'd have inside of your head would equate to at least 30ug of LSD.
Which generally doesn't feel like very much.
But define exactly inside of your head what that low amount of receptor stimulation would be providing?

You see for me and psychedelics at almost any dose, i suffer from synesthesia.
I've tried 2c-d as a Nootropic for a few days a couple years ago starting at 1mg - 5mg, it's was heavy. Lets just say that.
It's like i become more aware of gravity. Then sounds, music, passing conversations all of them had way too much of an "emotional" effect.

For example with Noopept, you could be reading the exact same Calvin and Hobbes book you've read your entire life. But you will literally have a deeper philosophical understanding
of some of the more subtle details without it being a "earth shattering experience" it's like the information you retrieve attunes to you naturally without there having to be a culmination of emotion baring down on your senses. There is also no emotional liablity at all. It's almost sobering feeling, but with enhanced vision... it's sooo weird.

I think it's the whole "over emotional" aspect that psychedelic substances can bring out, which while some of them maybe within the bounds of normal social acceptance.
a few of them might be a little bit too "out there" for the sober minded.

When i say something is like coffee. The stimulation you feel could be equated to the coffee that you are drinking.
Yet your visual field literally feels alive, or at least full of color without their being an affiliated psychoactive resolve where you are encapsulated by beauty.

I find that when i am on a substance with increased psychedelic awareness...
You get too caught up in the heads of other people without meaning to.
I know for a fact there are people out there who use like mdma and stimulants as nootropics.

Empathy is a good thing, and it can really help you learn alot about what you are learning.
But it can also turn people into a total maggots and goons. Who are too hung up on single things.

It's hard to be "hung up" on one thing with Noopept because you'll find yourself multitasking and being immensely productive.

 

[mission780]

I think you could, meaning that if you took like 100mg of noopept throughout the entire day.
By the time you go to bed, i'd imagine the feeling you'd have inside of your head would equate to at least 30ug of LSD.
Which generally doesn't feel like very much.
But define exactly inside of your head what that low amount of receptor stimulation would be providing?

You see for me and psychedelics at almost any dose, i suffer from synesthesia.
I've tried 2c-d as a Nootropic for a few days a couple years ago starting at 1mg - 5mg, it's was heavy. Lets just say that.
It's like i become more aware of gravity. Then sounds, music, passing conversations all of them had way too much of an "emotional" effect.

For example with Noopept, you could be reading the exact same Calvin and Hobbes book you've read your entire life. But you will literally have a deeper philosophical understanding
of some of the more subtle details without it being a "earth shattering experience" it's like the information you retrieve attunes to you naturally without there having to be a culmination of emotion baring down on your senses. There is also no emotional liablity at all. It's almost sobering feeling, but with enhanced vision... it's sooo weird.

I think it's the whole "over emotional" aspect that psychedelic substances can bring out, which while some of them maybe within the bounds of normal social acceptance.
a few of them might be a little bit too "out there" for the sober minded.

When i say something is like coffee. The stimulation you feel could be equated to the coffee that you are drinking.
Yet your visual field literally feels alive, or at least full of color without their being an affiliated psychoactive resolve where you are encapsulated by beauty.

I find that when i am on a substance with increased psychedelic awareness...
You get too caught up in the heads of other people without meaning to.
I know for a fact there are people out there who use like mdma and stimulants as nootropics.

Empathy is a good thing, and it can really help you learn alot about what you are learning.
But it can also turn people into a total maggots and goons. Who are too hung up on single things.

It's hard to be "hung up" on one thing with Noopept because you'll find yourself multitasking and being immensely productive.

This Noopept sounds very interesting. I suppose you might have a good synergy with it I am going to read more about it and maybe order to try for myself.
Are there any common side effects of Noopept?

 

[SONN]

Interesting this is such a hot topic of discussion atm because I just logged on bl to say my nootropic cocktail I tried this morning is making me feel very lazy and sedated feeling

I took .3 grams of psilocybin mushrooms
~13 mg noopept
Ginkgo extract
And theanine
And choline bitartrate
And a little bit of weed

I feel quite an effect but most of it is an anxlytic euphoria and an enhancedafterimage which is interesting but not necessarily making me feel smarter . Typing on my phone is being a bitrch but I have to write a paper later and will update.

 

[Psychonautical]

it's the mushrooms. They make human bodies derpy and technology seem funny.
If you were on like amphetamine or lsd, or something like that oddly
i believe technology would remain within the same field of function. Alien, psychedelics and a goddamn Cellphone would suck ass.
Everytime i see a Cellphone on psychedelics i generally want to smash it. They are evil little devices.
but then again that is my own manic neurosis.

You would have more fluid motion and less body drag, on almost any compound other than mushrooms..

so far in the 9 days i've been taking 100mg of noopept daily, i've noticed extreme cognitive enhancement. Everything is nowhere near as dull as it was.

i've only been mixing it with marijuana of various grades, and coffee.
occasional cigarettes.
But ultimately i enjoy where Noopept seems to be evolving my mind.

 

[mission780]

Interesting this is such a hot topic of discussion atm because I just logged on bl to say my nootropic cocktail I tried this morning is making me feel very lazy and sedated feeling

I took .3 grams of psilocybin mushrooms
~13 mg noopept
Ginkgo extract
And theanine
And choline bitartrate
And a little bit of weed

I feel quite an effect but most of it is an anxlytic euphoria and an enhancedafterimage which is interesting but not necessarily making me feel smarter . Typing on my phone is being a bitrch but I have to write a paper later and will update.

What kind of weed do you smoke?
If it is maily indica it can make you lazy. Better try sativa dominant weed, it will wake you up

 

[SONN]

I actually just took a dab of "shatter" or butane extracted thc purified to resemble glass. so a little bit of weed is totally an understatement and I probably felt extra lazy due to the mg of xanax I took over the weekend. Overall it was a pretty intense anxiolytic almost to the point of being overwhelming.

and the feeling on the body was as if my insides were made of clouds or pillows

I don't think ill be throwing in the weed or the mushrooms tomorrow haha in stead, some extended release amphetamine.

also, before you guys go crazy with Noopept, it should be noted that you should try to dose as small as you can to get your desired effect according to this

and this

and this guy
fig 1 demonstrates the effect of noopept administration: increasing expression of brain derived neurotrophic factor and nerve growth factor in rat hippocampus. Although what groups acute/chronc administration, etc is not supplied in the figure legend, also a housekeeping gene mRNA expression control would be good, but perhaps this is explained in the article proper.

table 2 shows that relative to saline control, acute noopept administration decreases both BDNF and NGF expression in the cerebral cortex but increases expression in the hippocampus. Additionally, noopept administration continued for 28 days increases BDNF expression but has no significant effect on NGF in the cortex, and again in the hippocampus both BDNF and NGF are increased over 2-fold.

increased mRNA expression is a good indication of increased protein (BDNF, NGF) content; although it is not confirmatory, as translational bottlenecks, increased protein turnover or other factors may be at play.

/qoute

apparently "acute" doses are less effective than small ones?