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How toxic is Mephedrone?

Ket is notoriously bad for you anyway.
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really?

I mean, norketamine, a first-order metabolite, bears nephrotoxicity, but mainly with severe overuse.

I would say (this comparison is really apples to chairs) that ketamine tends to be safer than any classical stimulant.

ebola
 
ebola? said:
really?

I mean, norketamine, a first-order metabolite, bears nephrotoxicity, but mainly with severe overuse.

I would say (this comparison is really apples to chairs) that ketamine tends to be safer than any classical stimulant.

ebola
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I'm pretty sure it does a fair amount of irreversible damage to your kidneys and bladder?
 
Boffhead said:
I'm pretty sure it does a fair amount of irreversible damage to your kidneys and bladder?
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It has done irreversible damage but only to people who would take multiple grams a day for long periods of time
 
Im assuming that the consensus with this stuff is that it is relatively benign at reasonable doses.

It appears quite weak that people can just cane entire grams of the pure powder relatively easily.

That is obviously very easy to do with bupropion, but bu is considered junk and not a respected stimulant.
 
Im assuming that the consensus with this stuff is that it is relatively benign at reasonable doses.
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No it's not. Bening and mephedrone are not words I would use in the same sentence.
 
Im assuming that the consensus with this stuff is that it is relatively benign at reasonable doses.
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Perhaps one could argue this if there were ANY peer-reviewed research on the shit. :)
There are some indicators that mephedrone isn't benign even at such levels. For example, during my one bioassay of the substance, at 200 mg oral, 50 mg booster, taken right at the peak, my pulse was RACING directly before the peak, and if it maintained that level, I would have sought medical attention.

ebola
 
^^Definitively not, at least not on my side, and I agree with FnB here.

Smyth said:
Im assuming that the consensus with this stuff is that it is relatively benign at reasonable doses.

It appears quite weak that people can just cane entire grams of the pure powder relatively easily.

That is obviously very easy to do with bupropion, but bu is considered junk and not a respected stimulant.
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Comparing apples with oranges. Buprenorphine vs. mephedrone is pointless. :\
 
^funny how the misunderstanding endures. i was referring to ebola?'s original comment on which fnb commented.

edit: okay now im confused as well. are we talking about ketamine or mephedrone? i assumed it was mephedrone, but ebolas comment was actually a comment on a post referring to ketamine. but this is the mephedrone thread
wacko.gif



massenkarambolage
 
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re: ketamine:

Well, yes, people can do multiple grams, sucked into redose traps ("I have to go back and rediscover 'the secret'!" ;)), but given the comparative lack of physical addictiveness or a come-down syndrome, the type of abuse that leads to kidney damage seems rare.

re: mephedrone:

Dosing at 1+ gm/day for multiple days in a row appears the norm. Addiction dangers are pretty much similar to other rapid-acting, short-lasting classical stimulants, only mephedrone appears more toxic. Many people are fucked. :)

Apples to Velociraptors. ;)

ebola
 
Comparing apples with oranges. Buprenorphine vs. mephedrone is pointless.
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I said bupropion which is more similar to mephedrone.

Bupropion is worth considering because its a licensed pharmaceutical.

You recall that sertraline started out as tametraline and was changed into something completely different.

I wonder if a retrosynthetically minded person would be able to trace where bupropion is coming from.
 
stupidity

I have taken mephedrone i do not usually have an addictive personality but my 1st time takin .5g i was wantin more. then afta this me and few friends found that we were takin it nearly everyday average 2/3g aday but once it was 11g in2days (by1person) but der was no cumdown so we kept takin eventually when i managed2stop it completely i was having severe nightmares cold sweets and i ad 4gotten the last time i had ate and i lost 2stone in total in a 5week period then my brain felt as if it was just mmmm floating around in my head every time i shook my head it felt as if it were just floatin around in water disconected as such also if takin this drug if u must dont put it up ur nose 1it burns da hell outa it 2nd me and my friends had alot of nose bleeds but that cood have just bn da amount we were takin. i did mix it with extacy twice 1st time was ok but 2nd was awful very bad cramps and shakes this stuff shood NEVA b mixed way and drug thats all just thought id tell ppl my experience
 
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