• N&PD Moderators: Skorpio

How toxic is Mephedrone?

^.........and one of the worst side effects was the complete destruction of the punctuation centre in the brain 8).

with good therapy you should get back use of commas, and with a lot of work you should get back paragraphs and sentences too.
 
i dont use commas and stuff like dat as u can c my spellin is shite it has nofin2do way drugs im a lazy fucker
 
Hi guys,
I've already posted something similar is a different meph forum, but i think this the right place for it, so here goes.

I got curious about this drug and decided to give it a try, and in a nutshell i took 400mg over the course of about 6 hours during a night out. Had an amazing, brilliant time.

Woke up the next day with chest pain and mild numbness/pins and needles in my left arm/hand. Both of which come and go but on the whole are fairly constant. They have been going on for about 6 days now, and at times can be a quite scary. I went to see a doctor and had a ECG, blood pressure and various other tests. And it all came back fine, apparently i'm perfectly healthy. Yet the strange symptoms continue.
Has anyone else else experienced anything similar? At this point i really hope it's not permanent as it can be pretty scary and troubling. I am wonder if or when its going to get better and go away...

:(
 
Look up this thread's speculation on toxic metabolites of mephedrone.
IMO, if you had a medical assessment and they claimed that you'd be okay, you should be fine in time, but you just need to catabolize all that nasty 4-methyl-ephedrine, etc. Did you tell your doctor that you took mephedrone?

ebola
 
vektor said:
^.........and one of the worst side effects was the complete destruction of the punctuation centre in the brain .

meta-discussion:

Granted, that post was hardly readable, but the guy seemed pretty panicked.

ebola
 
Look up this thread's speculation on toxic metabolites of mephedrone.
IMO, if you had a medical assessment and they claimed that you'd be okay, you should be fine in time, but you just need to catabolize all that nasty 4-methyl-ephedrine, etc. Did you tell your doctor that you took mephedrone?

ebola

No, i honeslty didn't have the balls, as the doc seemed pretty tired and pissed off anyway. I know, i should of told him, but i figured like alot of people of said, he's probably never heard of meph before. He asked if i'd done any stimulants and i told him the truth and said i had, 6 days ago. Really hoping these symptoms pass in time. Had a bit of a panic attack today about the pins and numbness for an hour, ok now though.

I'd also just like to say that i know that there are those who think this drug is only damaging to people who abuse it, I think i am pretty much clear evidence that this is simply not the case. If you've tried it, had a good laugh, and not experienced what I and some others have been going through i.e chest pains and numbness in my case from quite a small first time dose. And even turning blue for others. Good for you.
However if you've never tried it before, i have to tell you that in my opinion it simply isn't worth taking the risk. If i introduced it to a friend of mine and this happened to them i would feel horrible about it, as my friend who introduced me to it now feels. To be completely honest it has had me really worried for a week now. I've had plently of fun experimenting with other substances, stuff with at least a bit of research and experience behind it, going to stick with the tried and true :).

NEVER doing this stuff again.

(PS. sorry if i got a bit preachy, but nothing has ever had me so paranoid or worried before)
 
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I have taken mephedrone i do not usually have an addictive personality but my 1st time takin .5g i was wantin more. then afta this me and few friends found that we were takin it nearly everyday average 2/3g aday but once it was 11g in2days (by1person) but der was no cumdown so we kept takin eventually when i managed2stop it completely i was having severe nightmares cold sweets and i ad 4gotten the last time i had ate and i lost 2stone in total in a 5week period then my brain felt as if it was just mmmm floating around in my head every time i shook my head it felt as if it were just floatin around in water disconected as such also if takin this drug if u must dont put it up ur nose 1it burns da hell outa it 2nd me and my friends had alot of nose bleeds but that cood have just bn da amount we were takin. i did mix it with extacy twice 1st time was ok but 2nd was awful very bad cramps and shakes this stuff shood NEVA b mixed way and drug thats all just thought id tell ppl my experience


what an idiot. not for the typing, but generally....11 grams in 2 days... what a fucking idiot lol
 
Yeah, the effects this guy had could be expected with any drug you abuse, be happy you didnt turn purple and never abuse an unresearched chemical like that again.
 
Well, some self indugent chemists on this forum have managed to confuse many people including me who are looking for some basic understanding of the risks associated with the use of methedrone or Mephadrone. In simple terms, is there a difference?
 
mephedrone (4Methyl methcathinone)
methedrone (4-methoxy methcathinone)


looking at the structures Methedrone is probably more dangerous, because the related amphetamine causes severe cardiovascular side effects along with somethin that looks like serotonin syndrome and has killed quite a few people over the years.

neither are safe.

neither are worth the risk IMHO

leave them alone
 
4-Methylmethcathinone

Thank you for the response and information. I recently used 4-Methymethcathinone which was bought from the internet. It was more like whie powder and I thought that this stuff was kind of chrystal like. It did worjk though. Just worried after reading all the information on this site and I am somewhat confused about the differences. I am now aware that there are mainly two which sound alike; Meph and Meth but some companies advertise meph but when it arrives it is meth, if that makes sense.

looking at the structures Methedrone is probably more dangerous, because the related amphetamine causes severe cardiovascular side effects along with somethin that looks like serotonin syndrome and has killed quite a few people over the years.

neither are safe.

neither are worth the risk IMHO

leave them alone[/QUOTE]
 
Thank you for the response and information. I recently used 4-Methymethcathinone which was bought from the internet. It was more like whie powder and I thought that this stuff was kind of chrystal like. It did worjk though. Just worried after reading all the information on this site and I am somewhat confused about the differences. I am now aware that there are mainly two which sound alike; Meph and Meth but some companies advertise meph but when it arrives it is meth, if that makes sense.


the differences in physical form mean nothing, grind crystalline stuff and you get powder, recrystalise the powder and you get crystals. it is easy for white crystalline materials to be 1% pure and brown sticky lumps can be 98% pure.

on the whole the vendors themselves have no clue what they are selling, they rely on the analysis from the manufacturer and chinese manufacturers often create analytical reports, the vendors don't check. so their customers don't have a hope in hell

most of the material in circulation is the 4-methyl compound with 4-methoxy being much rarer (fortunately). however it really doesn't matter because neither of them are good for you.
 
mephedrone (4Methyl methcathinone)
methedrone (4-methoxy methcathinone)


looking at the structures Methedrone is probably more dangerous, because the related amphetamine causes severe cardiovascular side effects along with somethin that looks like serotonin syndrome and has killed quite a few people over the years.

neither are safe.

neither are worth the risk IMHO

leave them alone

How does PMMA cause those problems? Why would they occur with the cathinone, and wouldn't methedrone feel more like a fiercer drug than mephedrone if it was more prone to do really bad stuff through cardiovascular mechanisms and serotonin fever of some sort?

I'm not defending either, I'd just like to know if there's solid reason behind your guess except that PMMA makes methamphetamine seem nice and methedrone molecularly shares some of PMMA:s treats.
 
How does PMMA cause those problems? Why would they occur with the cathinone, and wouldn't methedrone feel more like a fiercer drug than mephedrone if it was more prone to do really bad stuff through cardiovascular mechanisms and serotonin fever of some sort?

I'm not defending either, I'd just like to know if there's solid reason behind your guess except that PMMA makes methamphetamine seem nice and methedrone molecularly shares some of PMMA:s treats.

there are a couple of general rules:

cathinones usually metabolise to the betahydoxy compounds.

the betahydroxy phenethylamines/amphetamines with a given substitution on the ring have much greater peripheral activity than the related amphetamines

PMA and PMMA cause spectacular rises in BP through vasoconstriction and their effect on the heart and have killed more than a few people

ergo these cathinones are a bad idea.

I really don't understand the logic of your post. how would such a vague concept as fierceness correlate to anything, in the same way how can you feel neurotoxicity. PCA in human trials was a nicely smooth anorectic, the fact it was ablating serotonin neurons. Aminorex and dexfenfluramine are likewise smooth but can do severe cardiovascular damage to people
 
PCA in human trials was a nicely smooth anorectic

do you have a link to the human PCA trials? i would love to hear more information about that, was it really described as "smooth" or lacking in noticeable side effects? i understand the point your making is that neurotoxicity cannot necessarily be "felt" but still, i find that quite astonishing.
 
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