I guess you're also suggesting that the crazy high doses don't have a disproportionately large amount of mind-fuckery? I.e. it remains clear? I guess I'll have to give it a go one of these days. I've never tried more than 40mg (and looking at my notes they say "try more"). Frankly I've never taken a particularly heroic does of any psychedelic thus far.
Oh definitely. Different synthesis, even by same method, may end up with different impurities, etc. Have had a bunch of batches that looked quite different from each other, but felt the same to me. Then again, I'm in Canada, so I guess we're getting different batches.
I assume that you mean 4-aco-dmt, which is of course quite different from "DMT" which always refers to n,n-DMT.