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Ethylphenidate Discussion Thread

Great post, Halif! I agree that ethyl can be compulsive, which is strange for me as I am really not much of a stimulant person either.

And footsy, I've experienced the same thing... lying in bed at night, trying to sleep, thinking maybe I should just go for it.

Probably a good thing I won't be getting anymore.
 
Have had another go with this, at considerably lower doses than before, and seems pleasant enough at lower doses. Lacks euphoria really, but that may be due to me taking loads of MPA. In fact the Ethylphenidate seems to have lifted my mood a little. The anxiety seems to be absent for all trials since I had that bad experience, and the comedown doesn't seem too bad, though perhaps slightly irritable (as I would be with MPA).

I'm planning a break with the MPA and am going to see if this might be a reasonable substitute. I'll be ordering 500 mg over Christmas, with the intent of investigating it as something to help with my low motivational levels.

I've also restarted my SSRI so maybe thats had an effect? Since resuming my SSRI my background anxiety level has plummeted massively, from fairly severe to low.
 
Theoretical LD = 104mg for adult male 75kg, sensitive?

Christ! said:
I've always thought the LD50 rates of amphetamines were kind of tricky to figure out, the amounts I see mentioned on a mg/per kg basis always seem kind of astronomical. I'm not sure if he'll be able to find a reference although I remember reading something like "fatal doses for children 200mg fatal dose for adults 1g" - but I can't remember what route of admin. that was and I don't think it was from a reliable source.
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I'll try to find the research - can't lay my hands on it right now - but some academic somewhere worked out that the theoretical LD for an adult male weighing 75kg with exceptional sensitivity to amphetamines would be 104mg, taken IV or smoked. Don't know why that stat. stayed in my head. :\
 
Jakeperson said:
Strange that EPH is so popular here.

I talked to a few Europeans about it and they all said it was shit and close to inactive.
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It does make you wonder whether we are talking about the same substance.

A small number of very reputable RC vendors have been selling EPH crystal in the UK since mid-December, allegedly very high purity.
 
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footscrazy said:
Well back on the topic of EP. I tried plugging some today. No real rush and it still took 15-20 mins to kick in. I do like the high better though it's still not amazing. It seems a bit smoother and less jittery than I felt after snorting it.
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footscrazy, what sort of dose were you plugging?

PS Glad to see someone taking the rational route of administration! I've yet to find a drug that doesn't work better plugged, in some way, than other routes of admin. Everyone out there who hasn't tried plugging - you're missing out! Big time! :)
 
lovepsychadelics said:
Most drugs take 24-48 hours to be eliminated, in the case of meth 72 hours I have found no academic research on the half life of this substance as yet.
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Methamphetamine takes ages to disappear because it has a MAOI effect. I've seen some reports that Methylphenidate half-life is relatively short, at 2-4 hours. Any chemists able to make a prediction about Ethylphenidate half-life?
 
Sameria said:
Even if such laws did exist (which I'm sure don't anymore) do you really expect law enforcement to adhere to them ?? They do so much dodgy shit on a daily basis - they are above the law. If they want to get a conviction they will more than likely get one.
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'Did you see yourself as above the law?'

'The law game is essentially a good game. I don't mind playing a game if other people stick to the rules they give us. But you can't get the guys who are enforcing it to play by the damn rules. They will break the rules at any cost.'

(Key Kesey, talking about being a fugitive in Mexico.)
 
^ Yeah, I described my experiences smoking it earlier in the thread. I tried smoking it in foil, it def hit me but it wasn't great, it doesn't burn well, it goes black and chunky and the puff feels dirty. When I inhaled it, my heart did this massive thump then stopped, then started up after this pause really rapidly. It feels stimulating but not euphoric or pleasant. My friend Drug_Mentor smoked it in a crakie and didn't like it, he says it makes a mess of the crackie, it does have an effect but it feels dirty, just bad for you.
 
for better results vaping try freebasing the ep, make eprack D:
 
How would someone get a substance like this tested if they don't have a gc-ms handy?

Want to get get this EP testing along with some MXE from the same source.
 
i do believe mr blonde got the ep tested, cant remember where he posted tho
 
^ It's somewhere earlier in this thread, though given certain circumstances not sure if that analysis can hold up to some of the latest batches going around and there have been varying reports on quality that people have given.

Christ!: I believe there was a lab in Europe doing testing for the public though that may have just been for pills.

Jakeperson said:
Strange that EPH is so popular here.

I talked to a few Europeans about it and they all said it was shit and close to inactive.
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When I knew I would be coming across EP soon, I looked it up and found a few of those reports from Europeans. A lot of them seemed to have been on the L-threo isomer, which if it follows the pattern that methylphenidate and amphetamine do, would be inactive or very weak.
 
I sampled a different batch of EP last night (an old sample that has been saved for quite some time - so it was bought before my dodgy batch). It was completely different from the first lot I had. I think the first one was adulterated with crap, perhaps mdpv like some reports have suggested, since that's what the physical effects reminded me off. This second batch was so different, no physical effects, a smooth speedy feeling - really enjoyable.
 
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footscrazy said:
I sampled a different batch of EP last night (an old sample that has been saved for quite some time - so it was bought before my dodgy batch). It was completely different from the first lot I had. I think the first one was adulterated with crap, perhaps mdpv like some reports have suggested, since that's what the physical effects reminded me off. This second batch was so different, no physical effects, a smooth speedy feeling - really enjoyable.
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I've come across two different 'batches'.


First batch I received late october. It was a fine crystalline powder, with some chunks or 'balls' of what looked like the powder. Chunks (not my picture but illustrates the exact 'chunks')

Second batch I received recently and it looked like the first batch only mixed with large crystals. I'm not experienced enough to tell the difference by effect, and didn't care much for the first batch...so hesitant to even bother with this lot.

Larger crystals

Someone will probably end up taking the EP that I have, and want to try and find out if it's contaminated, or if the first one was contaminated...and if possible try and find out what I actually have.

foots - With the most recent batch that was smooth and you ended up enjoying - can you describe its appearance compared to the other lot you tried?

Here's some info from someone who only tried the most recent batch -

Ethylphenidate - On observation this was contaminated or somewhat cut with something 90% to 10%, two chrystalized substances were isolated, the majority was clear, rough cut and salt-like shaped. While the minority was almost always oddly spherical, dense and pure white.

1st attempt at this whole substance (200mg oral/nasal over 9 hours): Euphoria, mild stimulation and concentration initially followed by mild paranoia, difficulty concentrating, mental cloudyness, headache, exaggerated pain and difficulty controlling frustration.

2nd attempt (250mg oral with an attempt to remove minority substance): very similar to firstbut with a noticeable change from euphoria (Dopamine binding) to stimulation (Norepinephrine binding) sfter 2.5 hours.
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Some of the first mentions of EP on this forum from ol' AS13 descibed his sample as 'a crystal rock [bro]'
 
There's an interesting scientific report on EPH's sister compound, methylphenidate (link) that concludes that MPH exerts no neurotoxic, but in fact neuroprotective effects in humans.

And there's another (link) that concludes that 'chronic methylphenidate treatment enhances striatal dopamine neurotransmission after experimental traumatic brain injury'.

Would someone with a greater understanding than I about these sorts of things be able to give an educated guess as to whether the same applies for ethylphenidate as well?

If these qualities of MPH are also present in EPH, then it's pretty awesome news.
 
Interesting stuff Pete. Thanks for posting.

I used MPH + dexamphetamine to treat my ADD-type symptoms last year...it worked quite well, found I could take less than half my usual dex dosage and add less than half (equivalent) MPH for better effects than either one on their own. Didn't seem to have any problems with tolerance either which was interesting...with plain old dex I find it becomes almost ineffective after 6 months at the same dose - I'm on a long break from stimulants for that very reason. Too bad medicare don't approve duel stim treatment (AFAIK)

I wouldn't have a clue if EPH has those same qualities that MPH has...Mr.B might have some idea.
 
That first link is stating that methylphenidate prevents neurotoxicity caused by the MPP+ ion (a metabolite of MPTP, some interesting reading for those who have not heard of these before) via blocking access through the dopamine reuptake transporter. To find out if ethylphenidate would also potentially confer this protection, we need to know if it binds to these transporters with a similar efficacy to it's homologue. This study claims that both racemic methylphenidate and ethylphenidate 'exhibited comparably potent low inhibition of the dopamine transporter, whereas ethylphenidate was a less potent norepinephrine transporter inhibitor.'

The second study is discussing the use of ethylphenidate in controlled cortical impact models of traumatic brain injury, and seems to show that methylphenidate improves dopamine release, maximal velocity of clearance of dopamine and increased affinity of the transporters for dopamine, all variables that were reduced by TBI. Also, although total striatal DAT expression was not improved by methylphenidate, membrane bound DAT expression was improved which is probably how V(max) and K(M) values were improved. This one is harder to show that ethylphenidate is likely to have these properties; the exact mechanisms by which methylphenidate improves dopaminergic neurotransmission is unknown, and although it is quite likely that ethylphenidate also would have these effects it is not a certainty.

Also important to note is that the neuroprotective effect shown in that first link has to do with a specific mechanism of action; blocking of the DAT to MPP+. Other neurotoxic compounds with different mechanisms of action may be able to bypass this, for example if they have a higher affinity for the DAT or cause toxicity through another path, not to mention that only dopaminergic neurons are protected and other neurons are still vulnerable.

Very interesting links, JSPete, thanks for that! I'm going to save those. :)
 
I haven't been following this thread because i'm not interested in stimulants. But your friendly neighbourhood drug dealers are selling this stuff now, calling it "E Powder" . This might be common knowledge but I haven't heard that name before. I don't know how much it costs in comparison to meth, as the friend is given free samples with his weekly meth purchases.
 
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