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Ethylphenidate Discussion Thread

Also interested on BA orally? Sounds harsh on the nose. Someone was saying they were concerned about consuming orally due to it's caustic properties? Anyone wish to expand?
 
I've done two small oral doses with virtually no noticeable effect. First one was 20mg and second was 50mg. I started with these low doses as I have no experience with stimulants and I am mostly interested in getting a boost in focus and energy to help me at work.

The 50mg may have helped me through a busy day, but it was subtle enough that I don't know if it was the EPH or I just had a good day.

Next stop - 100mg oral.
 
zomg said:
I'm 21 years old and my health is pretty good I believe, I smoke cigarettes and the most exercise I do really is walking/riding to Uni.. Don't participate in any frequent active sport but am slim and eat reasonably well.

No other medication except for Seroquell (I suffer from insomnia and these are the only meds i've been able to be prescribed) although I hate the side effects and use them maybe twice a month when I've been without proper sleep for too long.

It should be noted the sample you received initially is different to what is being sold now, instead of crystal it is now cut (informed by seller) though I doubt that is the cause for nausea.

I suppose I get nauseas pretty easily as often my stomach is upset when consuming anything from acid to ket to amphets/mdma. Just today I only had a small like of maybe 25 - max 50 mg and got significant nausea an hour so afterwards that built up. Think it was a mix of the terrible drip and drinking water to try and wash the taste away.

The harshness on the nose is concerning, blood from such small amounts. Snorted gently also as to have the chem sit in nostril to avoid drip. My nostrils have had a beating in the past also from crushed pills, ketamine, md + bk md crystal etc without ever having blood.

You say it doesn't sound right... What response could I have given that would explain the nausea/was there anything in mind? My 4 or 5 doses have been quiet small, maybe I need to have a decent amount in one go and then re asses.
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You seem like a normal person... So... I would say that the nausea was caused just by your tendancy towards getting this from any kind of stim.

Now the nose bleeding... Do you know what the vendor used to cut it? Why would they cut EP, it would ruin it totally. IMO wherever you are buying from is selling some shitty stuff and trying to make quick cash on shit product. Switch vendors. It could have been cut with a really nasty chem (jaggered bits of whatever they used I guess you could call it), and this may have caused the minor bleeding. Be careful.
 
Halif said:
I've done two small oral doses with virtually no noticeable effect. First one was 20mg and second was 50mg. I started with these low doses as I have no experience with stimulants and I am mostly interested in getting a boost in focus and energy to help me at work.

The 50mg may have helped me through a busy day, but it was subtle enough that I don't know if it was the EPH or I just had a good day.

Next stop - 100mg oral.
Click to expand...

100mg oral will DEF give you what you are looking for. I dose 100mg and redose every 45 mins or so about 50mg to 60mg (similar to coke dosage)...
 
so far 200 mg consumed over the last 12 hours; half of which spending time on blue light the other half playing assassin's creed Brotherhood. Man can i ever fucking focus in video games. Usually I can't focus on anything but online posts, small articles, things from varied readers, poetry (if it's short) but now I am a focus machine. River Dance. I'm definitely don't want to abuse these things but at even 20mg bumps they are effective and certainly more effective than benzos for being bored. Perhaps this is the honey moon stage.


Ethylphenidate deff gave me visual problems; i couldn't read, i could only type from touch typing classes.
It was like everything was just slightly off with a blue and red tint, slight blurring. Don't think it's from the phenezepenazepam i had as it had run its course pretty much.
 
Mr Blonde said:
Jake: Haven't tested solubility, but could post up some results a little later on. I don't IV, but let us know how it goes if you do. Given the burn, I'm not sure if I'm keen on plugging.
Click to expand...

Yeah I don't either really but I still wanna try methylphenidate IV, maybe ethyl is the better choice based on everything here.

2c-t-7 (and 2cx in general) has the worst burn of anything I have snorted but they don't burn from plugging so hopefully this won't either.
 
Going to be able to compare this substance head to head with coke soon, will make for interesting research!
 
--RobotRipping: thanks for the report. That's what I'm hoping to get out of it (River Dance LOL). I have the same issue with only being able to concentrate for short periods. I used to read a lot and enjoy watching films or playing games but now I can't do the things I used to enjoy because my mind just wanders off. I can't follow a narrative and when I try to read I find my eyes are just going over the words but I haven't taken in anything. Now, my job involves a lot of reading and I tell ya, I'm having serious problems getting it all done. I have to break everything down into short 10 minute bursts, which isn't really practical when you have thousands of words to read and process in a limited time.

I have considered going to the doctor and asking for help because it's becoming a real issue (affecting work and quality of life), but I just don't think it would go down well because the worst thing I ever did with my doc was confess to "abusing" codeine - that's when i found out my doctor isn't sympathetic to non-therapeutic use of medicines (i tried to suggest it was therapeutic, but can't argue with a doctor). I really regret mentioning it. I thought it would be better to be honest about everything but I think it went against my best interests.

Anyway, sorry to go off on a tangent. Today I will try 100mg (oral) and see if it helps. Hopefully someone who's in the same boat as me can get some useful info from my experiences and make my posts worthwhile.
 
If you can't argue with a doctor and get a point across, he's pretty much useless.

He is an expert on medicine, you are an expert on your own body.
 
Mr Blonde said:
My nose is pretty blocked up right now but I've had sinus problems for a little while as I mentioned. Will take it easy on the nose from now on.


Jake: Haven't tested solubility, but could post up some results a little later on. I don't IV, but let us know how it goes if you do. Given the burn, I'm not sure if I'm keen on plugging.



Methylphenidate isn't known to show quite the same cardiotoxic effects as cocaine; the latter has the ability to block sodium channels which is what causes it's anesthetic effects. This also contributes significantly to it's toxic effects on the cardiovascular system.

The FDA Pediatric Advisory Committee has discussed the cardiovascular risks of methylphenidate and as you can see in the minutes from their meeting, didn't seem to take it too seriously. It almost seems as if they were phoning it in that day. If you have pre-existing heart conditions or high blood pressure then methylphenidate, ethylphenidate and other stimulants in general should probably be avoided.

As for half-life, many drugs have very different elimination times. I can't find anything solid on ethylphenidate, apart from it being established that it's shorter then methylphenidate.

That link apparently only lets you view it once or something as I can't see the relevant text now after refreshing. :\
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about the clogged nose; each nostril will switch from being blocked, try laying with your head on one side for a whie.
Great post btw with some great info that i'm on the hunt for.
 
credentia1 said:
Also interested on BA orally? Sounds harsh on the nose. Someone was saying they were concerned about consuming orally due to it's caustic properties? Anyone wish to expand?
Click to expand...

The BA of methylphenidate itself is not that great. The extra methyl group should make it more lipophilic, but there is limited data available on how this improves oral absorption. With AS13 suggesting 100mg orally, this means that perhaps it's oral BA is similar to that of methylphenidate.
 
On oral dosing from Adv. DD. He is referring to a 20mg oral dose of ethylphen

^ not if you eat it, methylphenidate and presumably ethylphenidate is subject to extensive 1st pass metabolism (80-90 %), most of it being metabolized before it gets anywhere near the limbic system
Click to expand...
 
zomg said:
Has anybody else experienced nausea from even just one small line? Is there any info/experience on the BA when had orally?

Comparing to coke is a far cry. Just a slightly better Ritalin (who woulda thunk?). When I blow my nose I notice that each nostril has bled a little bit.

Unsure how I feel about this stuff. Does make you talk a lot ... but I'm unsure if I would really want to put any more than 100mg up my nose in an evening due to how harsh it is. The drip is disgusting also so sublingual not really an option. Obv theres plugging but is hardly appropriate in a club/socially etc.
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I don't find it harsh if you crush it up really fine to snort it, makes snorting an RC a treat (sarcasm). I'm going to do 100mg sublingual and go to to a pub so the social aspects will really be tested as I am really quite introverted but this stuff makes me go on and on i have to watch myself.

Also i'll get nauseous if i snort too big of a line but it passes very quickly, probably just my body lacking proper nutrition

update: sublingual seems almost inactive after about 40 minutes so I'm not sure how effective this ROA is. Or much tolerance is at play but 50mg up the nose still feels wonderful.
 
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Jakeperson said:
Yeah I don't either really but I still wanna try methylphenidate IV, maybe ethyl is the better choice based on everything here.

2c-t-7 (and 2cx in general) has the worst burn of anything I have snorted but they don't burn from plugging so hopefully this won't either.
Click to expand...

I couldn't be bothered to find out solubility myself, but here is some information from ChemSpider:

Log Octanol-Water Partition Coef (SRC):
Log Kow (KOWWIN v1.67 estimate) = 3.27

Boiling Pt, Melting Pt, Vapor Pressure Estimations (MPBPWIN v1.42):
Boiling Pt (deg C): 345.59 (Adapted Stein & Brown method)
Melting Pt (deg C): 109.36 (Mean or Weighted MP)
VP(mm Hg,25 deg C): 2.49E-005 (Modified Grain method)
Subcooled liquid VP: 0.000168 mm Hg (25 deg C, Mod-Grain method)

Water Solubility Estimate from Log Kow (WSKOW v1.41):
Water Solubility at 25 deg C (mg/L): 400.4
log Kow used: 3.27 (estimated)
no-melting pt equation used

Water Sol Estimate from Fragments:
Wat Sol (v1.01 est) = 787.08 mg/L
Click to expand...

So estimates are between 400.4 and 787.08mg per mL. That sounds promising for such a potent compound. :)
 
VP(mm Hg,25 deg C): 2.49E-005 (Modified Grain method)
Click to expand...

This seems to be referring to vaporizing it, but I have to admit I am lost as to how to interpret. I don't know what their modified grain method refers to.

Also, ethylphenidate seems to be more soluble in water then methylphenidate is! This is unexpected, as you are increasing the length of the hydrocarbon chain and typically this leads to a greater lipophilicity. Maybe I need p_d to step in here, but from the logD charts I'm looking at both methyl and ethylphenidate show similar solubilities in water as the cation, which is what you will have when you dissolve the substance in question in water.
 
Thanks Mr Blonde for the info, some very interesting reading. I didn't mean the cardiotoxic effects were the same as coke I was just generalising using a drug people perhaps may be more familiar with and that ethylphenidate may have cardiotoxic effects at high doses. I was not to focused when I wrote that LOL. I'm in good health, work out etc. and felt some mild palpitations after 200mg (1 x 100mg and 2 x 50mg doses over 3 hrs) I will have a look for any academic publications that examine half life. Has anyone noticed numbness if dosed sublingual. Good point re: cardiac health and stims.
 
^ I dabbed a little left over powder on my gums and didn't notice any numbness... didn't expect to either. Just had a... 'chemical' taste for lack of a better word. Kind of bitter.
 
yeah alot of it's being cut apparently... I hate that, they did that to the buphedrone I ordered, everytime I vaped it my lips would go numb
 
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