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  • EADD Moderators: Pissed_and_messed | Shinji Ikari

EADD Heroin Discussion v. XXII -- Brucey Bonus Beetles all round!

Mate it was a LOT more than that. A 100mcg/hr fent patch actually contains around 16mg of fent and still has lots left in it when you take it off. It needs a lot more in it that it delivers due to the diffusion gradient that transdemal absorption needs. Anyway i started using then bucally cos the just werent cutting it transdermally and when you use the bucally you get almost the entire amount in a few hours. Id estimate i was doing through about 65mg of fent a day. Thats nothing to be proud of but thats how it was.
 
I am entirely aware of the efficiacy of the matrices and the subcutaneous reservoir, fairly well versed in the stuff I have to say. ;)
Were they matrix or gel? The plastic gelatinous gunk that replaced the gel actually made buccal pretty much inefficient, you just absorb a fraction of the actual amount but the dose you do get hits instantly and feels subjectively stronger but, as you say, it lasts no more than 4 hours. The plastic patches were actually pretty fukkin' efficient at preventing abuse, unlike most mechanisms, but they did so by preventing the patch being useful at all.
 
Ive been prescribed both but mainly the matrix ones. Actually there is an interesting study by Jansen Ciag when the were making exclusively gel patches. Other companies were switching to matrix as they said they were less abusable. Anyway Jansen did an experiment to show how incredibly easy it is to extract 98%+ of the fent from a matrix patch simply by immersing it in either IPA or ethanol (simple vodka for example) and leaving for a few hours. After which almost all the fent is in the alcohol which can then be evaporated. The best way of using the martix bucally is to rough the inside of your mouth with a toothbrush then swab the inside of your cheeck with an IPA swab and stick the patch in there.....

PLEASE DONT ANYONE TRY THIS AS ITS INDESCRIBABLY DANGEROUS. THE AMOUNT OF FENT DELIVERED IS HUGE AND WILL KILL ANYONE WHO DOESNT HAVE A SUPERHUMAN TOLLERANCE....

Edit...actually the plastic part of the matrix patch is just inert plastic. The xrug is mixed into the adhesive on the sticky side.
 
Yeah, I scored the other night. It was my mate -- let's call him Art -- it was his birthday last week, so as a treat I arranged to score some Incredibly Strong Drugs™ for some Friday night shenanigans. Also posted some down to Jess, in the hope that it might help take her mind off reality for awhile. Art had to go home early because his girlfriend (who isn't into gear) had a really bad toothache, so I gave him a couple of 30 mg. dihydrocodeine tablets (that I'd been keeping for after this ran out, but her need was greater) for her. Then I forgot that I was suppose to be going to my parents' for dinner tonight .....
 
Interestingly im feeling pretty shitty today. As most already know i had an awful WD experience last year but had been off everything for months until my recent ankle surgery where i was given a few days of tramadol in hospital...now im feeling quite sever withdrawl from that. I didnt think that would be possible but it seems like after suffering a horrible prolonged WD even a few days of therapeutic opiates set you back. Urgh...im sick of this shit.
 
englandgz74 said:
Interestingly im feeling pretty shitty today. As most already know i had an awful WD experience last year but had been off everything for months until my recent ankle surgery where i was given a few days of tramadol in hospital...now im feeling quite sever withdrawl from that. I didnt think that would be possible but it seems like after suffering a horrible prolonged WD even a few days of therapeutic opiates set you back. Urgh...im sick of this shit.
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Its a common problem among former opiate / opioid dependents, where you only have to use the class of drug again for a couple of days to re-induce withdrawl symptoms. Its a recognised phenomenon in former addicts, and its known as withdrawl kindling. It may explain the high relapse rate among opiate / opioid addicts, as the fast onset of WD symptoms can turn a one off lapse into a full blown relapse.
 
Yeah thats what i feared. Its odd though that even a mild opiate like tramadol or codeine sets it off. It seems like you just have to refraid from ANY opiate drugs full stop. I wonder if this is a life long thing or if brain chemistry is permanantly altered...
 
Its a lifelong thing, chronic, prolong opiate addiction changes your brain chemistry in ways that are so subtle that they go to the core of your psychological self. I don not believe anyone understands the mechanisms behind WD kindling, but its likely to be a leftover from the subconscious learning that your brain will have undertaken during previous WD experiences that may resurface if you start pushing those receptors again, regardless of the relative low strength of tramadol and codeine compared to similar narcotics. My first opiate experience was from 120mg of codeine phosphate and it felt like I was in heaven. Its only after I discovered its big brother that I lost the ability to use it for its abuse potential, so they are still reasonably potent drugs, all things considered.
 
It's of note that just one month of Morphine use induces observable changes at the neurological level - grey matter is reduced in the amygdala and portions of the interior cortices whilst elevated in the cingulate regions and the right hypothalamus.
The amygdala links to the orbitofrontal cortices and is responsible for learning and reinforcing stimulus-behaviour-reward patterns of behaviour.

Neuroplasticity in response to Morphine administration rapidly induces reward seeking behaviour while inhibiting awareness of risk and consequence.

Paper with topographical images
Typical change in mass: 3%.
 
Hi guys, I thought about making a new thread to ask this but as so many of you are so knowledgeable here I thought I'd just post.

So 18 days ago I went on holiday to a country which don't allow maintenance. I had a meth script that I couldn't take so decided to just CT on the trip. Bad idea, I know. But--thank god for Immodium--it actually went ok. I hadn't used any opiate (bar lope) for 18 days. So my last dose of meth was 18-19 days ago. The WDS were actually ok, not as bad as I thought. But on return to our lovely country I thought it a good idea to score a bag of low-quality (id guess 15-25%) H. Nowhere near the quality of the stuff I usually get through dn, but still feel that feeling we all love.

My question-will my use of .3 of #3 send me right back to the days of my full blown synthetic meth tolerance. Or will the wds be more manigible. Id like to chip at opiates going forward (please dont judge, its my crutch) at a max of once a week use. Do you think I will be right back where I was when the Meth was coming out my system? Thanks, and sorry for the disjointed text; kinda matches my train of thought about everything right now. :)
 
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Sid said:
I don't think I'll be robbing my gran or looked upon with disgust by my family anytime soon. )
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Couldn't help but say this, but talk about some famous last words. I have heard so many people say this in the past only to fall into addiction and the type of addictive behaviours that they never thought themselves capable of. Including myself. Sorry for the cliche but if you keep playing with fire, you will get burned eventually.
 
Ive been mainly sticking to methadone lately. Going to quit again in a few months when my course finishes. I'm going to university in September and need all my wits (and cash) about me.

Have either a couple of 8mg subutex or kratom to ease it a little over 2 weeks and a house to go to and a friend to keep me company. I'll use kava and phenibut as well, and save up my lyrica prescription to dose heavy for the restless legs. I would love to get my hands on some clonidine but i might get it on the net.

I cant use benzos as ill be down to almost nothing in my valium prescription and dont want to screw it up. I want to be off the valium for uni because it affects my memory. I'll learn to deal with anxiety without drugs, and using different receptors when I really need some chemical assistance.

The WDs should be very manageable.
 
I came off a huge dose of methadone cold turkey last year and the WDs were fucking horrific mate. I had a clonidine script and it helped a little bit but not much. The main problem is that people underestimate how long the wds last and any ancillary meds like pregabalin or diazepam will become a problem in themselves if used for months on end (my wds lasted 7 months).

I wish you all the best bro and hopefully your wont be as bad as mine were but fuck me it was rough.
 
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