Ive used Dextromethorphan as an antidepressant now for 13 years. I found it's effects similar to small doses of PCP. I've been trying to find a Dr. to help me get off the Dextromethorphan now for 9 years with little success. Xanax worked for me, but after 4 months the Dr. took me off of Xanax (you know how Drs. are when it comes to benzodiazapenes) I have been prescribed every other antidepressant under the sun with no success. I've had limited success with Wellbutrin, but it's main effect has been as an anti-smoking aid. But as far as I am concerned, one antidepressant is about as effective as the next (i.e. not at all).