In cases like this, more so with dipipanone, phenadoxone, and levomethadone for chronic pain -- and of course other narcotic analgesics as well -- I have used potentiators for the narcotic like cyclizine, hydroxyzine, meclozine, diphenhydramine, bromphenamine, phenindamine, phenyltoloxamine, doxylamine, tripelennamine, promethazine, dexchlorphenamine, cyproheptadine, &c as well as benzodiazepines, meprobamate, carisoprodol, phenprobamate, tybamate, methocarbamol, and other such sedative, hypnotics, and tranquillisers, and others used clinically for this purpose; also the usual adjuncts, potentiators, and side-effect and main effect- moderating drugs like stimulants (methylphenidate with caffeine) tricyclic antidepressants and related drugs (cyclobenzaprine, nortriptyline, trazadone) atypical analgesics with dirty pharmacological profiles (orphenadrine, tramadol, nefopam) Nsaids (naproxen) anti-convulsants (topirimate), oral and transmucousal ketamine, other muscle relaxants (mephenoxalone, chlorzoxazone, tizanidine) beta blockers (clonidine) catabolic steroids (dexamethasone, methylprednisolone) paracetamol, chemically unrelated weak opioids like meptazinol, ethoheptazine, tilidine, tramadol, and only under doctors' supervision stronger ones like morphine, tapentadol, dextromoramide, nicomorphine, ketobemidone, or hydromorphone.