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Dihydrocodeine Products in Oz

100 ml and 200ml, I should add it really kicks in properly after around two hours.
 
any ideas on histamine over dose ichy
what anti histamines can ya snort
deos the histamine stay in system
i had 800mg codeine, then endep, then sme anit histamines some snort some swallowed, mixing anti histamines bad
i kow all these things gonig to increase effects also had 4 drinks
 
As far as histamines go I have no idea, never needed any since I'm used to the itchiness from proper smack this itchiness wasn't worth trying to deal with since it was minor in comparison.

Oh and this stuff gave me gas, got annoying after a while.
 
Just a quick heads up.
The last 200ml bottle I purchased actually had 215ml in it.
I double checked the amount with my medicine cup, and checked it with a 10ml syringe to make sure it wasn't out, and I definitely got 215ml.
Just thought I'd let you guys know incase you 'eyeball' your doses based on whats meant to be in the bottle.

Histamine wise I take 10mg of promethazine with my syrup. Doesn't take away all of the itchies, helps alot though, but it does add to the sedative effect, and can make smaller amounts punch a little more so keep that in mind.
 
Oh forgot to add that I got the laxative effect from 135ml. Hadn't happened before, but by Jesus it caned me.
I took 2 imodium tablets, that seemed to have helped a little though.
 
You're either not taking enough or your body is slow to metabolize the drug and doesn't convert it into enough morphine/hydromorphone. Codeine and dihydrocodeine are metabolized by the same liver enzyme I believe, so that explains why neither effect you much. Personally, I'm an awesome metabolizer of both.
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I've actually seen it said in research that the amount of dihydrocodeine that becomes hydromorphone is almost negligible; dihydrocodeine, unlike codeine, provides most of the high by itself.
 
Mr Blonde said:
I've actually seen it said in research that the amount of dihydrocodeine that becomes hydromorphone is almost negligible; dihydrocodeine, unlike codeine, provides most of the high by itself.
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So would that mean there is no ceiling effect as it doesn't need to be converted to get the high.

Also no one has answered this, does it also produce a histamine release?
 
I think that's right, you can re-dose it as much as you want.

And yes it does cause a histamine release, which is why it's not suitable for faster MOA's, not unlike codeine. Could be fatal if you try an IV or anything 8o
 
The cytochrome P450-2D6 (CYP2D6) is the major enzyme mediating O-demethylation of dihydrocodeine to dihydromorphine. In contrast, nordihydrocodeine formation is predominantly catalysed by cytochrome P450-3A (CYP3A).

Does anyone know which causes the majority of the high? the dihydromorph or dihydrocodeine.

All the sorbitol in this product could be useful if you are a regular opiate user and usually backed up. Are there any other side effects from consuming ~40g of sorbitol apart from the diarrhoea gas etc?
 
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You guys are going to get this banned soon.

And it is really the only thing that works for pain without a script.

Do some research on the internet before posting. Google gives some great results when you search for DHC.

Remember that the media are all over codeine at the moment.
 
really the media
they best fuck off its good to help with strong opiate withdrawals
what media
i think they more onto the nurofen with codeine
not onto the other uses; well until some EDIT current affairs spin doctor gets this info

edit madmick19
 
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just a quick reminder that what you post on here becomes public property, australian and other countries media and law enforcement have access to this public resource ad do read it,

please take responsibility for what you write in this forum and remember that other people who may not have the same knowledge might take yur word for truth.......
 
If you guys think this thread is detrimental to the image of these forums and serves no harm minimisation purpose you should delete it, sure most of us can moderate what we say but if you ultimately thinks this will be of no use then you should remove it. I'm sure all the information regarding the active ingredients is readily available online if they wish to find out about it.
 
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remove codeine from easy access, increase illicit opiate market and thus crime and all the other unwanted shit. fucking dumbcunt idea. goddamn.

what would the government rather? people occaisonally walking into a chemist to buy a pack of pills that they can use to relax at home later, or have those same people going out onto streets or into shady houses to cop street drugs that they can go home and use, and risk being poisoned by some unknown cut, or getting ripped off and then getting angry and possibly violent?

at least while codeine is in chemists they can tax it, god, where there is demand there shall be a market; removing products from otc is just fucking silly.

surely ruddy is smarter then that
 
So say you took codeine (~100mg) then 45mins later dyhydrocodeine, would the fact that the codeine is using a lot of the enzyme up mean that it makes the dihydro last a lot longer? I wonder if anyone wants to try out my hypothesis.
 
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100mg of codeine doesnt saturate your enzyme; 400mg would.

and if your enzyme was working to full capacity, it wouldnt make the DHC last longer, it would simply make it effect you less.

so to answer your question, no it wouldnt make it last longer. but if your only taking 100mg of codeine in the first place, u can stuill take ur DHC with it or 45 mins later and enjoy the combo of both.
 
ifonly said:
and if your enzyme was working to full capacity, it wouldnt make the DHC last longer, it would simply make it effect you less.
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Thats what I mean, if its working to less then full capacity, eg partial saturation from codeine it would take longer to metabolise the dihydrocodeine, resulting in blood levels of dihydrocodeine lasting longer.
 
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