Opioids Defeating the new OC time release

[lowrider6967]

Very Wise ! When I occasionally eat them, that does make some sense. Altough I believe by breaking them down first, they lose their binding properties. Otherwise they would just stay or rebind in the shot glass of coke, everytime you stirred it.

i was woundering the same thing,if your soaking them in c cola and u still have balls of slim even if some of the good stuff released from the slime wouldnt it just rebind if u drank it all?

 

[lowrider6967]

als i did a soak in cranberry juice it seams every thing dissolved no slime left havent tried it yet.(drank it)also left a dark purple almost rubber piece left.

 

[Pegasus]

Very Wise ! When I occasionally eat them, that does make some sense. Altough I believe by breaking them down first, they lose their binding properties. Otherwise they would just stay or rebind in the shot glass of coke, everytime you stirred it.

Taking it little by little is the easiest physical way to defeat any time release, for sure...

 

[GratefulJam]

I have found the best way without any chemical manipulation is to split into several pieces (8?), crush individually between teeth and suck/slurp/"massage" with toungue, i get a whole 60 to break down in like 15 mins, still some "goo" left in teeth but disolves completely in another few minutes. Because of the surface area and the way they disolve i believe there is no chance of regellin in the stomach and keeping the time release in tact, although some may be inescapable...seems the saliva and toungue worked great, this is only increased with addition of citric acid or "fruit snacks", sour patch kids, etc. i have not tried straight sugar/citric acid mix like in the bottom of the bag/@grocery store bins. granted there is no rush like sniffing, etc. although its relatively easy after using a simple pill splitter to covertly and quickly ingest without time release. this is how i will continue to do for my chronic pain, without having to rely on the actual use of the time release (in which case i would need a much higher dose!) for now i do this in the morning and at night, and treat with percacet for breakthrough a couple times a day. Nothing like my old us of OC as IR meds along with normal ingestion, but much better than 4-6mg of oxy released an hour! hope this helps, especially for those in pain. peace.

 

[GratefulJam]

Another curiousity about new Oxycontin fomula op, ive heard that there is an "inner capsule" that if broken neutralizes the oxycodone. has anyone else heard about oxycodone nuetralization if pills are tampered with, or is it just the gel polymer that binds and keeps time release. ive had the thought in the back of my mind about if the oxy were rendered inactive if pills were broken from day 1..BUT, in my experience this is not the case, but i also take breakthrough medication and am aware of placebos. any insight?

 

[clementines_ghost]

I continue to experiment with the citric (lactic & malic seem to work, too, but may just be potentiating the action of the citric acid), and just wanted to pop in and let y'all know that I had the idea of trying that Sour Warheads liquid spray candy...I thought 'hey! liquid citric acid, spray a little puddle of it on my tongue, soak the OPs in it, voila' but for some reason the liquid from this product does NOT melt the gel the way the citric acid/sugar combo from SPKs/other sour gummi candy does. I think the spray just sort of disappears off your tongue too quickly. Also, that spray shit is just gross.

If anyone is playing along and trying out the citric acid/sugar solution, make sure you give it a couple tries if it doesn't seem to work perfectly the first time; for some reason, for me, the OPs seem to get stronger and stronger every time I do it.

 

[l!ghtning]

like I have said it was only a matter of time till they popped up. And YES they are here, Toronto - Canada!! .. many docs are also offering Hydrocodone - a friend got 40mg or so?? and showed them to me, They have a HARD plastic ball within the 1st layer of powder .... and are impossible to play with.

I look forward to hearing more on the new Oxy 's soon.

keep your heads up and sunglasses on.

Short version

Does anyone have any information about the equivalent of OPs having arrived to Canada, or has any Canadian recently picked some up from the pharmacy and if so, were they the OP style version? The quoted poster suggests that the new OPs have indeed come to Canada, but his post isn't very clear.

TL;DR

I'm confused by the quoted post. Are you saying the Canadian OCs have been changed to American-style OPs? Can someone else confirm this? If so, what is the new imprint on them (if the American ones are now OP, and Canadian ones are or used to be CDN, what do the imprints say now)?

Also I see you're talking about hydrocodone with a 'hard ball'; hydrocodone is a completely different drug, which doesn't come in 40mg as far as I know (unless that's the total amount of drug he received)? Also hydrocodone in Canada in tablet form I believe comes with APAP (Hycodan); alternatively it comes in syrup form. Are you talking about the hydromorph-contins maybe?

Please post more info, or can anyone else comment. it would be appreciated, I don't want to waste my money on a Canadian version of "OPs"

 

[dntcheckthtbxdoc]

FOR ALL THE PEOPLE THAT WANT TO EAT EM AND HAVE THEM KICK IN QUIKER...... do this for you who want to (supposedly beat the time release) i dont see how thats a abuse way of doing these pills but: take some white vinegar or vinegar that health gurus drink little amounts of and let you pills dissolve in that in little dixie cups prior to taking and then BAM your pills the cancerous (Oxy Plastic) will kick in real quick with the boot you are looking for!!! that sour sugar shit is great but litterally will eat the skin off your taste buds and tongue i stopped eating that shit due to hat ....Also imagine how hard that shit is on the teeth in awhile youll start looking like a tweeker, let alone the acids in the actual OP's....just my 2cents.....ENJOY =-)

You all can relax cause supposedly breaking these is pointless for two reasons: 1) someone just mentioned that Ethex will forsure be distributing the original Oc's til 2015 min. so get a good nights rest no need to sweat it at all !! 2) Generic Oxycodone IR's made by Mallinkrodt have the same exact amount of mg's as the name brand Roxi's forsure or get the name brand (Xanodyne) ! If your Doctor writes you Oxyplastic he/she will write you Oxycodone IR's give it a shot, I did. The Mallies are good fucking pills !


This should relieve stress from the most of us. Remember These generics are said to be in nicer neighborhoods that aren't full of gangs and violence and chit, from what i read about them. Also instead of calling everyone and asking them which is extremely hard to do perfectly right in every way w/o out stepping out of bounds and getting to personal w/ there class 2's, which they are told they don't even have to discuss w/ anyone, anyhow go in the Walgreens branch of question and take a transcript of the medicines your insurance company pays for that your doctors prescribes you so they know you mean business. It's the paper thats mailed to you that has every single med you have filled and all the info about them, the count, the price, fill date....etc. Take that around to diff. walgreens to show them your serious about having a script........End of discussion

Mallinkrodt Roxi 30's aren't that bad afterall !!!!!!!
Read this all the way through anyone thats bashing Mallinkrodt at all.
http://www.bioportfolio.com/resource...one-30-Mg.html

 

[sciencefundie]

Some science on the new OPs...as in what works best to separate the good stuff and make it IR

Reference:
Household Solvents..

"when exposed to extraction in saturated baking soda solution at 60° C for 5 minutes, the dosage form releases less than about 15% of the opioid, preferably less than about 11% of the opioid; (1) when exposed to extraction in a cola soft drink at 60° C for 5 minutes, the dosage form releases less than about 45% of the opioid, preferably less than about 30% of the opioid; (m) when exposed to extraction in 100 proof ethanol at 60° C for 60 minutes, the dosage form releases less than about 33% of the opioid, preferably less than about 26% of the opioid; (n) when exposed to extraction in vinegar at 60° C for 60 minutes, the dosage form releases less than about 33% of the opioid, preferably less than about 20% of the opioid; (o) when exposed to extraction in saturated baking soda solution at 60° C for 60 minutes, the dosage form releases less than about 33% of the opioid, preferably less than about 23% of the opioid; (p) when exposed to extraction in a cola soft drink at 60° C for 60 minutes, the dosage form releases less than about 60% of the opioid, preferably less than about 45% of the opioid; (q) when exposed to extraction in a panel of extraction solvents including vinegar, hot tea, saturated baking soda and a cola soft drink, each at 250C for 60 minutes, releases less than about 20% of the opioid, preferably less than about 15% of the opioid; (r) when exposed to extraction in a panel of aqueous buffer extraction solutions ranging from pH 1 to pH 12, each at"

Microwave..
"As can be seen by these extraction results, only 4% (1.6mg) or less of the oxycodone dose was extracted from the microwaved Test Capsules after 5 minutes of extraction in each of the extraction liquids. After 60 minutes, only about 14-10% of the oxycodone dose was extracted in any test liquid. These data show that the Test Capsules resist rapid extraction or dose dumping"

Smoking/Chasing (very bad for you, and not efficient at all)
"Test Capsules and the single lot of SR Control tablets were evaluated in triplicate. Each Test Capsule was cut open and the liquid contents squeezed into a sample dish, and each SR Control tablet was ground with a mortar and pestle and then transferred to a sample dish. The aluminum block was stabilized at 2800C prior to initiating the study. The covers were swabbed for oxycodone at 3, 5 and 10 minutes, and the samples were analyzed using HPLC. The results of the volatilization study were as follows: average oxycodone recoveries following volatilization at 2800C (data in the form of mean oxycodone recovered with standard deviation (SD), reported as a % of initial dose): Test Capsules = 2% (0. at 3 minutes; 4% (2.1) at 5 minutes; and 12% (2.1) at 10 minutes. SR Control tablets = 12% (2) at 3 minutes; 11% (2) at 5 minutes; and 10% (2) at 10 minutes. These data are depicted in Figure 19."

Chewed: Increases absorption rates, but does not defeat time-release/anti-abuse mechanism(s). Peak (plasma levels) decreases from about 4 hours to 2 hours by chewing. Coke-Cola extraction process described above accomplishes the same a chewing, i.e. powering the pill. So roughly 40-60% of the total dosage will be effectively the same as instant release, peak less then 1 hour with remaining 40-60% absorbed the same as chewing.
"As can be seen, vigorous mastication (chewing) of the OXY Test Capsules increased the mean Cm3x from 40.5 ng/mL to 82.3 ng/mL. However, relative to the IR Control oral solution, the C1112x for the chewed Test Capsules was significantly lower and occurred at a significantly later time. The mean T1113x for the chewed OXY Test Capsules decreased from 5.52 hours to 2.67 hours, as compared to 1.07 for the IR Control oral solution."

Bio Availability: Oxycodone: Very good orally, 85-95%
"inally, the relative bioavailability based upon the AUCiast of the three 80mg Test Capsule formulations (OXYl- OXY3) was very good (>80%, ranging from 83.39% to 90.27%"


So basically Coca-cola is the best...personally I microwave 40-50 mL of coke for like 25 secs, then chop up the OP as fine as I can with a good chef's knife, and dump it in the coke. Wait 15-20mins, microwave again (now a mixture of coke and chopped up OP) for 25 secs, wait 30 mins and drink. The longer you let it sit in the coke the more Oxy will become IR, plateauing around 4-5 hours...if you can wait that long lol. Drink, chase with beverage of choice, clean off residue from glass with a toothpick or something, fill up again and drink again as to not lose any product. As a long time (mostly) eater this method works better than chewing the old ones, or even powdering and parachuting, since the time release was still in effect, albeit not for very long

 

[grafitti]

Some science on the new OPs...as in what works best to separate the good stuff and make it IR

Reference:
Household Solvents..

"when exposed to extraction in saturated baking soda solution at 60° C for 5 minutes, the dosage form releases less than about 15% of the opioid, preferably less than about 11% of the opioid; (1) when exposed to extraction in a cola soft drink at 60° C for 5 minutes, the dosage form releases less than about 45% of the opioid, preferably less than about 30% of the opioid; (m) when exposed to extraction in 100 proof ethanol at 60° C for 60 minutes, the dosage form releases less than about 33% of the opioid, preferably less than about 26% of the opioid; (n) when exposed to extraction in vinegar at 60° C for 60 minutes, the dosage form releases less than about 33% of the opioid, preferably less than about 20% of the opioid; (o) when exposed to extraction in saturated baking soda solution at 60° C for 60 minutes, the dosage form releases less than about 33% of the opioid, preferably less than about 23% of the opioid; (p) when exposed to extraction in a cola soft drink at 60° C for 60 minutes, the dosage form releases less than about 60% of the opioid, preferably less than about 45% of the opioid; (q) when exposed to extraction in a panel of extraction solvents including vinegar, hot tea, saturated baking soda and a cola soft drink, each at 250C for 60 minutes, releases less than about 20% of the opioid, preferably less than about 15% of the opioid; (r) when exposed to extraction in a panel of aqueous buffer extraction solutions ranging from pH 1 to pH 12, each at"

Microwave..
"As can be seen by these extraction results, only 4% (1.6mg) or less of the oxycodone dose was extracted from the microwaved Test Capsules after 5 minutes of extraction in each of the extraction liquids. After 60 minutes, only about 14-10% of the oxycodone dose was extracted in any test liquid. These data show that the Test Capsules resist rapid extraction or dose dumping"

Smoking/Chasing (very bad for you, and not efficient at all)
"Test Capsules and the single lot of SR Control tablets were evaluated in triplicate. Each Test Capsule was cut open and the liquid contents squeezed into a sample dish, and each SR Control tablet was ground with a mortar and pestle and then transferred to a sample dish. The aluminum block was stabilized at 2800C prior to initiating the study. The covers were swabbed for oxycodone at 3, 5 and 10 minutes, and the samples were analyzed using HPLC. The results of the volatilization study were as follows: average oxycodone recoveries following volatilization at 2800C (data in the form of mean oxycodone recovered with standard deviation (SD), reported as a % of initial dose): Test Capsules = 2% (0. at 3 minutes; 4% (2.1) at 5 minutes; and 12% (2.1) at 10 minutes. SR Control tablets = 12% (2) at 3 minutes; 11% (2) at 5 minutes; and 10% (2) at 10 minutes. These data are depicted in Figure 19."

Chewed: Increases absorption rates, but does not defeat time-release/anti-abuse mechanism(s). Peak (plasma levels) decreases from about 4 hours to 2 hours by chewing. Coke-Cola extraction process described above accomplishes the same a chewing, i.e. powering the pill. So roughly 40-60% of the total dosage will be effectively the same as instant release, peak less then 1 hour with remaining 40-60% absorbed the same as chewing.
"As can be seen, vigorous mastication (chewing) of the OXY Test Capsules increased the mean Cm3x from 40.5 ng/mL to 82.3 ng/mL. However, relative to the IR Control oral solution, the C1112x for the chewed Test Capsules was significantly lower and occurred at a significantly later time. The mean T1113x for the chewed OXY Test Capsules decreased from 5.52 hours to 2.67 hours, as compared to 1.07 for the IR Control oral solution."

Bio Availability: Oxycodone: Very good orally, 85-95%
"inally, the relative bioavailability based upon the AUCiast of the three 80mg Test Capsule formulations (OXYl- OXY3) was very good (>80%, ranging from 83.39% to 90.27%"


So basically Coca-cola is the best...personally I microwave 40-50 mL of coke for like 25 secs, then chop up the OP as fine as I can with a good chef's knife, and dump it in the coke. Wait 15-20mins, microwave again (now a mixture of coke and chopped up OP) for 25 secs, wait 30 mins and drink. The longer you let it sit in the coke the more Oxy will become IR, plateauing around 4-5 hours...if you can wait that long lol. Drink, chase with beverage of choice, clean off residue from glass with a toothpick or something, fill up again and drink again as to not lose any product. As a long time (mostly) eater this method works better than chewing the old ones, or even powdering and parachuting, since the time release was still in effect, albeit not for very long

i have found a beverage that will destroy the gel , let sit about 60 minutes , a 80 chopped into tiny pieces , the beverage becomes gel free , is this common or is it a a good find , i put 1 80 in it and got off super fast , the bubbles attack the pill , dissolving it in a very short time , the beverage is drank by millions every day so it is nothing bad , does anyone care ?

 

[olskoolrollrz]

i have found a beverage that will destroy the gel , let sit about 60 minutes , a 80 chopped into tiny pieces , the beverage becomes gel free , is this common or is it a a good find , i put 1 80 in it and got off super fast , the bubbles attack the pill , dissolving it in a very short time , the beverage is drank by millions every day so it is nothing bad , does anyone care ?

could it be like that antacid stuff that fizzes up when you add water???i care....Thanks 4 the info....our Pharmasist for the last 2 years keeps insisting there are no generic 80s...so we are stuck with the op s...so yea i would like to know

 

[Jabberwocky]

just another reminder to everyone this is about defeating the OP time release, not a discussion on whether your pharmacist will order in generics or whatever.

please keep it on topic.

 

[MgmtBlue]

bullshit

Wow, that's deep. Your post history is quite telling. Frankly, I couldn't give less of shit whether you believe me or not. 8)

 

[lovebrisvegas]

ive been using alcohol swabs to wipe OP-80 pill coatings with no problems? comes off really easily? or is that just a colouring thats coming away not that plastic shit?

 

[lovebrisvegas]

ive been using alcohol swabs to wipe OP-80 pill coatings with no problems? comes off really easily? or is that just a colouring thats coming away not that plastic shit?

yeah, I see grinding and putting it in coke gets like 85% bio avail - is this option ultimately better than IV'ing?

im finding it hard to find an exact ultimately best method for any gel-wax pills

 

[accessdenied12]

Cutting

I just cut an OP80 in half took half and cut it again and then ate the two pieces from half, going to see what happens, but it didnt look like mush or anything like people were talking about. It looked like powder actually a few pieces of powder fell off on my finger and i licked it, tasted fine to me.

 

[DavidStayzFadedd]

^
You're thinking of it wrong. He gets these for swimming, Phelps tosses him them and they inject them together.


And fuck, now I won't be able to do lines of OC and coke together when I have lots of money. Oh well snorting things doesn't even work as well for me as most people... I'll just spend that money on coke to do sublingually...

haha dude ive done linez of OC and with hydromorphone.... itz alright but damn, linez of OC and coke sound so good.. tha old oc'z of course.. havnt tried tha new op'z but isnt there a way to defeat most of the time release or watever by microwaving it in shot glass of coka-cola? i read that sumwhere..

 

[DavidStayzFadedd]

ive been using alcohol swabs to wipe OP-80 pill coatings with no problems? comes off really easily? or is that just a colouring thats coming away not that plastic shit?

ya itz just tha coating... dosnt affect tha release or anything.

 

[DavidStayzFadedd]

i have found a beverage that will destroy the gel , let sit about 60 minutes , a 80 chopped into tiny pieces , the beverage becomes gel free , is this common or is it a a good find , i put 1 80 in it and got off super fast , the bubbles attack the pill , dissolving it in a very short time , the beverage is drank by millions every day so it is nothing bad , does anyone care ?

so u should just powder up a op 80 and put it in coke? then microwave? god damn... im tryin to get high not fucking make a science project. fuck purdue or watever for doin thiz, i think they''ll be back.. they were makin alot cash from thoze OC thingz. its almost like legal heroin, well tha old one'z almost were.........

 

[arthunter888]

I don't see why this would not work to make virtually instant-release oxycodone for oral use.

1) Shave OP with hose clamp as fine as you can get until you have your desired dose.

2) dump powder into cola/soda, let sit for 8-12-hours. (I don't see a need to heat if you let it sit long enough)

3) Drink.

I would imagine that sitting in cola/soda for 8-12 hours would resemble being in stomach acid and it would all be released over this time period. Does anyone see a problem with this method?