Try Effexor, that has some opiate activity.
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Role of the opioidergic system and nitric oxide in the analgesic effect of venlafaxine.Gültekin H, Ahmedov V.
Department of Pharmacology, Erciyes University School of Medicine, Kayseri, Turkey. [email protected]
The noradrenalin and serotonin re-uptake inhibitor venlafaxine has an analgesic effect that is independent of its antidepressant activity; however, the mechanism of this effect remains to be elucidated. This study was performed to investigate the possible roles of the opioidergic system and nitric oxide (NO) pathway in the analgesic effect of venlafaxine. Eighty Wistar rats of both sexes were allocated to 10 groups. The hot plate test was used to assess the antinociceptive/analgesic effect. The temperature of the hot plate was adjusted to 52.5+/-1 degrees C, the cut-off period was set to be 50 sec; licking of the hind paw was used as a sign of pain perception. Venlafaxine alone (25 mg/kg) showed marked analgesic activity (p0.05). Coadministration of low-dose naloxone (2 mg/kg) and both doses of L-NOARG (20 and 40 mg/kg) with venlafaxine (25 mg/kg) did not modify the analgesic effect but high-dose naloxone (4 mg/kg) decreased it significantly (p
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If your lucky you could try for Tramadol, but this is unlikely... depending on where you live you could get this otc.
Bup is almost never given for depression, but if you were going to try and get it for that purpose there is a range of bup patches now that would be a much more appropriate dose for this type of problem.