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Bupe Buprenorphine for depression?

sixpartseven said:
This being said, don't go out and get an addiction just to Suboxone for depression. In my opinion, yes, Suboxone worked wonderfully as an anti-depressant, but not the same way normal anti-depressants worked. It's hard to put exactly into words what I mean by that, but I guess it could be summed up by saying it's a good anti-depressant for opiate addicts. It gives us the mind-set and motivation to want to stay clean and do better things. In that way, it brings us out of the depression that readjusting to normal life inevitably causes and helps us move on. Someone who hasn't been to those depths doesn't need to be brought out of them.
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Is it as simple as saying that a big part of the depression is caused from opiate abuse and suboxone is merely relieving that depression by filling in the receptors?


bagochina said:
Bupe as an anti-d just doesnt make sense for me. I have been taking subs for a long while and I can honestly say that bupe is more a depressant for me. It is very tough to fill that void that IV heroin & whatever would fill for me, suboxone absolutely doesnt do it. Bupe allows me to function while trying to carry on with my life. The hard part is trying to get accustom to living a life not on the edge, the lull of normal life or the waiting for normal life is well boring.

Could it be the bupe that is making me depressed or is it just a typical stage in recovery? I would give anything to go back in time and change how heavily I lived in the drug world, but I cant I am left to deal with this jig-saw puzzle called life.

peace,
seedless
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You are more experienced than me in just about everything on the subject, but I did notice I started to feel depressed on suboxone after being on it for a while.

The longest time I was on it was 14+ months, 12 months maintainence and a slow 2+ month taper.


Inevitably ended up addicted again and now back on suboxone.


I think I just need to use suboxone occasionally once I get off of it.

I get depressed on it after long periods of time and I get depressed when I haven't taken any opiates/opioids for a while. Don't have much of an explanation except that the depression I have when off of all opiates, feels like a slow timer that gets reset once I take an opiate. If I can get to that point again, just have to work on spreading out those 'reset' uses.
 
i have read somewhere that (suboxone) looses its anti d feeling in 2.5-5 months. I am not sure how true this is but i have been on sub for a while and im not happy from it at all any more. I used to love it but now i jus wanna stop i have massive headaches like my head is being beat in by chuck liddell (abiggmooofaaaaaka) lol if any one else will elaborate on how they think would b appreciated well im out ricc
 
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ok i was jus thinkin i think u need a benzo there cheap and help can be addicting but what cant
 
or i was on zoloft for a while but it made me pooo all day and no sexdrive so no ssris
 
I REALLY DONT KNO suboxone is a weird chemical i would say that .02 would not have much a affect but it could make u sick .I have been on sub for a long time i have used opiates while on it never har (precip) withdraw i would say try it man i have been on sub for 15 months good luck and bless u
 
actually would u like to switch to sub? it helped me so much i would still b using if i was on methadone cause i use drugs thats what I do........ and when i use h or oxy or any opiate i dont feel it no matter how much i do so i am thankful for sub now i actually dont even think about noddin its a thing of the past . and the anti depressant qualities of sub only last 2-5 months but its worth the switch there is hope u will make stay strong and always think how u were before u were using u can do it again. its hard long haul but if ur strong u can do it stay with clean people and away from (FRENIMIES) PEACE BROOOTHA
 
So u want the bupe for anxiety? I honestly am not sure how effective it would be im on bupe it def does not control anxiety
 
sixpartseven said:
^ Um, yeah? Most doctors aren't just going to go off your word that you are addicted to opiates though. They will examine you and most likely drug test you. If they don't piss test you, then you aren't free to lie about it. There are quite a few physical signs of withdrawal that they look for. If those aren't there, then chances are they aren't going to give you Suboxone.
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Exactly.

You can lie and try if you want to, but your blood pressure, your heart rate, and several other things are going to be signaling you as a non-opiate user to the doctor.

It's ridiculous to assume you could just pretend opiate WD.
 
Dolomiti said:
Part of the reason for giving bupe or methadone is so the patient *doesn't* have to experience cold turkey withdrawals.
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You're actually quite ignorant about WD symptoms.

You have to be in withdrawal before taking buprenorphine. Otherwise, you will experience something known as precipitated withdrawal.

The idea with methadone or buprenorphine is it's an alternative to taking a drug like heroin where you're functioning and stable...not to completely avoid withdrawal symptoms completely (which is impossible).

It shouldn't be that hard to take an opiate before a piss test.
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That's not going to help you. Being high on opiates is not going to get you a suboxone prescription, they will require you to come in while withdrawing.
 
I do not think it is legal for a doctor to do that since it has not been approved by the FDA to be used for depression. I'm usually wrong though. Good luck!

On a second note, I do know people who are clean from opiates thus having no WD symptoms of any kind, but still get Suboxone on the street to be used for their depression.
 
euphoricc said:
So u want the bupe for anxiety? I honestly am not sure how effective it would be im on bupe it def does not control anxiety
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Opiates affect Dopamine, ultimately increasing the amount of Dopamine produced and the amount of pleasure felt.
 
Artificial Emotion said:
Can someone answer my question if they know the answer? Thanks.
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If you took the Sub (even that small amount) it would knock the Methadone off the receptors possibly causing you to have WD symptoms. And because Buprenorphine has very high binding affinity for the opioid receptor, the μ receptor in particular, taking the Methadone afterward would not make you completely better until the Suboxone was out of your system. It's kinda like a catch 22, but not really. I'd stick to one or the other. And besides, the anti-depression effect caused by the Suboxone is also there with the Methadone. They both do the same thing, in a general broad aspect.
 
While I think bupe is effective at treating depression, you are making a very serious decision if any doctor would prescribe you the drug. Typical doc's cant prescribe it, despite its schedual, they need to go through a class (in the USA) and can only treat a certain number of patients.
Bupe is highly addictive, and in the long run, could worsen the depression exponentially, I know, as I've been there.
I dont doubt, however, it could be beneficial for some people out there. just beware.
 
Artificial Emotion said:
Yes I'm aware of precipitated withdrawal caused by buprenorphine, but will it really be an issue if I'm only taking 200ug?
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Yes, I'm pretty sure it will be an issue. We just explained how buprenorphine has a more potent binding affinity to the mu opioid receptor. Unless you're aiming for the WD's I wouldn't bother with buprenorphine, unless you've been clean from methadone for a good few days.
 
What about doses even lower than that? What I really need to know is what is the lowest effective dose of buprenorphine for depression? I mean it's not like maintenance doses will be needed...
 
Artificial Emotion said:
What about doses even lower than that? What I really need to know is what is the lowest effective dose of buprenorphine for depression? I mean it's not like maintenance doses will be needed...
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You will build a tolerance to (I believe its called Tamagesic when its 0.4mg or whatever) You will eventually have to up your dosage. Anyways, bupe isnt like an SSRI, it doesnt take a month to kick in. It works while its in your system, then it wears off, and you have to take it again. To really benefit from bupe, for depression, I believe a dosage of at least 1mg (depending on prior opiate exp). You need to "feel" it. You're not staving off w/d, or fighting pain, your fighting mental pain, so you need that "bupe" feeling. all in all, i dont reccomend it, its a very strong drug, once you've taken it for a month - you've dedicated yourself to it. Tapering to zero is very difficult for a lot of people. Just think long and hard. Sorta like, if someone paid you $500,000 to fight mike tyson...think long and hard bout it.
 
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