I'd have thought the only way an increase in dosage could extend duration would be that the dosage itself was that abnormally high it was enough to overwhelm whatever particular enzyme is responsible for metabolising and ridding the substance at hand, that quite simply even when all available enzymes are at work, there's still not enough of them to take care of the entirety of the substance circulating your body in the normal timeframe.
I know that doesn't quite make sense, but I'm sure you know what I mean. It's like if the job at hand (metabolising the LSD) is too great for the number of workers (monoamine oxidase?) available, not all of the work can be taken care of at once, and some must be left until a later stage when more workers are available.
I know that doesn't quite make sense, but I'm sure you know what I mean. It's like if the job at hand (metabolising the LSD) is too great for the number of workers (monoamine oxidase?) available, not all of the work can be taken care of at once, and some must be left until a later stage when more workers are available.