I don't understand why people have such opposition against plugging. The most confusing thing I often read is people recommending IV over rectal administration
(generally over the internet). To me it is just a minor procedure and it doesn't take more than 15 minutes for the whole procedure - end to finish. Flush out any poop, crush, mix, plug your pill(s) and clean up. Once you get "familiar" with this part of the body in strict medical sense, there aren't any downsides I can think of. I'm pretty sure it's healthy as well to give yourself a small enema every now and then to clean things up.
It's just a body cavity which you clean out and squirt some liquid into. Ten milliliter maximum volume mentioned above sounds strange. From my personal experience, ass can hold pretty damn much liquid. The little amount used for plugging isn't going up the colon unless you're hanging upside down. It's not gonna make you gay. You're not going to puncture anything or harm yourself with a pencil -shaped oral dosing "syringe" (official use: giving liquid medicine into your child's mouth).
The drug I usually plug is oxycodone. It's nice not having to worry about your stomach contents at all. None of the IV -use dangers nor shitty nasal bioavailability. No variables once you have your technique down. It also hits you a lot faster than oral route and I'd be crushing Oxycontins either way (apparently US harder formulation than we in Europe though).
Crushed Concerta -pills must be the hardest thing on earth to plug. Or at least getting all that sticky syrup absorbed. Even this situation was solved just by flushing the MPH out with around 20 ml of saline solution and re-plugging it. The colour matched with the scary reddish "liquid" I had put in. I don't recommend plugging Concerta though, very much hassle in comparison to other ROA's.
Oh, and you can even throw most common boosters into the mix. What a great way to make my entry here to BL. Been reading for a long time so might as well start writing too.