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Gabapentinoids The Lyrica (Pregabalin) Mega Thread v 2.0

bignbrown said:
i get this scripted now, and my doctor knows i have a history of benzo abuse but was fine giving me these.

Afaik they are GABA drugs but they work differently to benzos? so they dont down regulate the gaba receptors like benzos do?

Can someone explain to me how they work?

thanks
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anyone know this? it says it increases gaba levels, but it doesnt down regulate them?
 
L0cky said:
i think lyrica could be a potential doping for sport its hard to get tired on it but i hear a lot of people actually get fatigue from lyrica.

i actually know a guy that did a running marathon with no experience while downing 150 mg lyrica
2 hours before the race and had no problem with running or feeling tired till the end
and actually came in at a decent time.
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Yeah, doping is my forte :D or at least i'm most interest in reading and researching those kind of substances. I know i could never use Lyrica for that since even 75 mg makes me tired and 150 mg makes me into a complete zombie (and i have an insane benzo tolerance).
 
IVXLCDM said:
I'm not too worried about that, I take it with 300mg of temazepam and 300mg of seconal. I feel like a extremely drunk state for about 12-24 hours, (I don't know if thats a good thing)



When I first started doing a large amount alone, I did get tachycardia and it made anxious (obviously). Now it doesn't, about a month later. How much do you ingest?

Holy shit, I just realized I took over 9000mg today over the course of ~7 hours...I don't really feel too much though.
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Well temazepam is good for possible seizures too since it has anticonvulsant properties, just don't combine 9000 mg pregablin (or lower doses) with Tramadol, that's a real seizure trigger combination there!

Lyrica has the effect of acting as an anti-epiletic in moderate doses up to 600 mg, but when going higher it actually lowers the seizure threshold and can trigger epileptic attacks.
 
I've got a question for you guys that are experienced with this drug. So, I am a pain patient and before my opioid therapy was started they tried all sorts of non-narcotic meds on me to make sure that I was taking the least potent drug and dose that would mask my pain. I tried up to 300mg daily with this stuff 150 qAM, 150 qPM and did not receieve any benefit, end result was a treatment change (new drug).
However I'm currently on opiates and they just aren't cutting it, and I'm wondering if adding this on top of an opiate has helped anyone else, or does it magnify the effect in any way. I'm looking for more non-narcotic relief if I can get it (crazy, I know haha). But honestly, has anyone had any experience with a combination with opiates and did they have positive effects?
 
scottd420 said:
I've got a question for you guys that are experienced with this drug. So, I am a pain patient and before my opioid therapy was started they tried all sorts of non-narcotic meds on me to make sure that I was taking the least potent drug and dose that would mask my pain. I tried up to 300mg daily with this stuff 150 qAM, 150 qPM and did not receieve any benefit, end result was a treatment change (new drug).
However I'm currently on opiates and they just aren't cutting it, and I'm wondering if adding this on top of an opiate has helped anyone else, or does it magnify the effect in any way. I'm looking for more non-narcotic relief if I can get it (crazy, I know haha). But honestly, has anyone had any experience with a combination with opiates and did they have positive effects?
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yes holy fuck they are better than the opiate + soma combo imo....if i add in lyrica to my opiates my whole body gets numb as hell and it synergizes with the high so well...add in some weed = <3
 
laCster said:
yes holy fuck they are better than the opiate + soma combo imo....if i add in lyrica to my opiates my whole body gets numb as hell and it synergizes with the high so well...add in some weed = <3
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I use Lyrica 150 x 2 daily and love this combination. But, hell, I'll add Soma if I have it too =D
 
i heard about this herb gotu kola so im trying it out. usually i think herbs are a load of shite but this one is good. it has an effect similar to pregabalin but without the dizziness.

so im on a combination of pregabalin 300mg + 3.75g goku cola. seems good feeling relaxed but motivated just loving playing my guitar. much cheerier than usual and enjoying conversations with people and stuff.

im gonna throw in a couple of beers in a wee while. good times.

weird question - do you think you can smoke pregabalin?
 
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dunno how this being a gaba drug and being an anti convulsent at low doses, it can trigger seizures at higher dosage.
 
i dunno where people get this info about pregablin causing seizures i think it might be ones of those myths that goes around i dunno.

anyway, i went ahead and plugged 150mg of pregabalin. i read reports that its about twice as potent that way so great, its more cost effective. im feeling so pregged up right now :)
 
yeah apprently its about twice as potent that way. go for it. it was my first time plugging and it was so easy.
 
could pregs be used like a benzo, i had too much weed off myfriends and it has made me shakey and panicky, woul d pregablin calm me down
 
bignbrown said:
could pregs be used like a benzo, i had too much weed off myfriends and it has made me shakey and panicky, woul d pregablin calm me down
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lyrica and cannabis is one of my favorite drug cocktails...its sort of like being drunk but without the nausea and spins, sort of like GHB as vision gets blurry as fuck and colors appear magnificent


to answer your question, yes lyrica has great anxiolytic properties and will help you feel more normal
 
so how was it plugged overall? did it increase the potency? Or just a quicker onset, did it feel any different?
 
Yeaaah man when i saw the commercial for this shit on tv and it said it was NOT an nsaid i knew it would fuck you up like any DECent pain killer.
Tylenol is shit, even for headaches whats teh point of having it in production:|
New slang term here: High guy- man i just got so pregnant
Friend- the fuck man??
 
laCster said:
yes holy fuck they are better than the opiate + soma combo imo....if i add in lyrica to my opiates my whole body gets numb as hell and it synergizes with the high so well...add in some weed = <3[/QUOTE

That sounds like where I want to be brother. I appreciate your help like crazy, this may just be the trick for me. Plus, who doesn't love smoking herb?
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so how was it plugged overall?
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i would say that thers not really any benefit to plugging and that its probably better just to swallow it. it hits you faster when plugged but i dont think its any stronger.
 
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